Uveitis
Objectives
Define and classify uveitis anatomically, clinically
and etiologically
Describe the signs and symptoms of different types
of uveitis and identify the differentiating points
List the complications of different types of uveitis
List the investigations needed in selected cases of
uveitis
Describe the treatment of different types of uveitis
Uveitis
Anatomy of Uveal
tract: (Uvea= Grape)
1- Iris
2- Ciliary body
3- Choroid
Uveitis
Definition:
Classification:
- Anatomical.
- Clinical.
- Aetiological.
Uveitis
Anatomical Classification:
1- Anterior uveitis
2- Intermediate uveitis
3- Posterior uveitis
4- Panuveitis
Uveitis
Clinical classification:
1- Acute uveitis: <3 months
2- Chronic uveitis: >3 months
Uveitis
Aetiological classification:
1- Associated with a systemic
disease, e.g.:
a- Spondyloarthopathies
b- Inflammatory bowel disease
c- Nephritis
d- Non-infectious multi-system
disease
e- infectious systemic disease
f- Diabetes
Oral ulcers
VKH
Uveitis
Aetiological classification:
2- Infections:
a- Bacterial: tuberculosis.
b- Fungal: Candidiasis.
c- Viral: Herpes Zoster.
Uveitis
Aetiological classification:
3- Infestations:
a- Protozoa: Toxoplasmosis.
b- Nematodes: Toxocariasis.
Uveitis
Aetiological classification:
4- Idiopathic: 50%
(most common cause).
Anterior uveitis
Symptoms:
1- Acute anterior uveitis:
2- Chronic anterior uveitis:
Anterior uveitis
Signs:
1-Circumcorneal
injection:
Anterior uveitis
Signs:
2- Keratic
Precipitates
KPS
Anterior uveitis
Signs:
3-inflammatory
cells
Anterior uveitis
Signs:
4- flare and
hypopion
Anterior uveitis
Hypopyon
Anterior uveitis
Signs:
Pupillary
miosis
Anterior
Uveitis
Miosis
Anterior uveitis
Signs:
IOP
Anterior uveitis
Signs:
Iris nodules
Complications of anterior
uveitis:
1- Posterior synechiae:
2- Cataract.
3- Glaucoma:
4- Cyclitic membrane
formation and phthisis bulbi.
Intermediate uveitis
Symptoms:
Initially, floaters
later, decreased visual acuity due
to macular oedema.
Signs:
Cellular infiltration of vitreous
(vitritis).
Posterior uveitis
Symptoms:
1- Floaters
2- Impairment of visual acuity
Posterior uveitis
Signs:
1- Cells, flare, opacities and
posterior vitreous detachment.
2- Retinitis:
3- Vasculitis:
Posterior uveitis
Chorioditis
Retinitis
Retinal vasculitis
Investigations
X ray
Skin tests
Serological
HLA typing
Treatment:
1- Cycloplegic and Mydriatics:
2- Steroids:
Topical or periocular injection
Intravitreal injection of steroids
Systemic steroids
3- Immunosuppressive agents
4- underline cause