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Pyrazinamide Drug Study

This document provides information on pyrazinamide (PZA), an antituberculotic drug. It lists the drug class, dosage, mechanism of action, indications, contraindications, adverse reactions, and nursing considerations. PZA is a bacteriostatic and bactericidal drug used to treat active tuberculosis in adults and children, in combination with other antituberculotic drugs. Common adverse reactions include allergic reactions, loss of appetite, nausea, vomiting, and increased uric acid. Nursing considerations include monitoring liver function tests, serum uric acid levels, and potential serious adverse reactions.

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anreilegarde
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4K views1 page

Pyrazinamide Drug Study

This document provides information on pyrazinamide (PZA), an antituberculotic drug. It lists the drug class, dosage, mechanism of action, indications, contraindications, adverse reactions, and nursing considerations. PZA is a bacteriostatic and bactericidal drug used to treat active tuberculosis in adults and children, in combination with other antituberculotic drugs. Common adverse reactions include allergic reactions, loss of appetite, nausea, vomiting, and increased uric acid. Nursing considerations include monitoring liver function tests, serum uric acid levels, and potential serious adverse reactions.

Uploaded by

anreilegarde
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

DRUG DOSAGE MECHANISM OF INDICATIONS C/I ADVERSE NURSING

CLASS ACTION REACTIONS CONSIDERATION


Anti- 250mg/5ml Bacteriastatic/bacteri Initial treatment of Hypersensitivity MILD Monitor periodic liver
tuberculotic OD AC X cidal against active TB in adults and to PZA  Allergic function tests
2MOS Mycobacterium TB children with other anti reactions  SGPT
TB drugs after the Acute hepatic  Loss of  SOPT
Converted to primary treatment has disease appetite
pyrazinoic acid failed.  Nausea- Monitor serum uric acid
susceptible to strains Lactation vomiting level
of Mycobacterium  Increased
which lowers the pH Acute gout uric acid
level of the  Joint pain
environment.
SERIOUS
 Sideroblast
ic anemia
 Pellagra
 Seizures
 Low
platelet
count
 Nephritis
 Gouty
arthritis
 Drug-
induced
hepatitis

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