Scribd
Upload
131 views3 pages

Drug Study: GENERIC NAME: Acetaminophen TRADE NAME: Tylenol

This document summarizes information about the drug acetaminophen (Tylenol). It is classified as an antipyretic and nonopioid analgesic that inhibits prostaglandin synthesis primarily in the central nervous system. It is well absorbed orally and widely distributed throughout the body, including into breast milk. Most of the drug is metabolized by the liver and excreted by the kidneys. Adverse effects include potential liver toxicity in overdose situations or with other hepatotoxic drugs like alcohol. Nursing considerations include assessing pain and fever, monitoring liver and kidney function with prolonged use, and educating patients on proper administration and toxicity risks.

Uploaded by

Linda Adamson
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as RTF, PDF, TXT or read online on Scribd
131 views3 pages

Drug Study: GENERIC NAME: Acetaminophen TRADE NAME: Tylenol

This document summarizes information about the drug acetaminophen (Tylenol). It is classified as an antipyretic and nonopioid analgesic that inhibits prostaglandin synthesis primarily in the central nervous system. It is well absorbed orally and widely distributed throughout the body, including into breast milk. Most of the drug is metabolized by the liver and excreted by the kidneys. Adverse effects include potential liver toxicity in overdose situations or with other hepatotoxic drugs like alcohol. Nursing considerations include assessing pain and fever, monitoring liver and kidney function with prolonged use, and educating patients on proper administration and toxicity risks.

Uploaded by

Linda Adamson
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as RTF, PDF, TXT or read online on Scribd

DRUG STUDY

GENERIC NAME: acetaminophen

TRADE NAME: Tylenol


CLASSIFICATION: antipyretics, nonopioid analgesics

ACTION: Inhibits the synthesis of prostaglandins that may serve as


mediators of pain and fever, primarily in the CNS. Has no anti-inflammatory
properties or GI toxicity. Therapeutic Effects: analgesia and antipresis.

PHARMACOKENETICS

Absorption:Well absorbed.

Distribution Widely distrbuted. Enters breast milk.

Metabolis and Excretion: 85-95% metabolized by the liver. Metabolites


may be toxic in overdose situations. Excreted by the kidneys.

Contraindications/Precautions

Contrindicated in: Hypersenistivity. Products containing alcohol,


aspartame, sacharin, sugar or tartarzine shoud be avoided in patients who
have a intolerance to these compounds.

Use Cautiously in: Hepatic disease/renal disease. Chronic alcohol abuse.


Malnutrition.

ADVERSE REATIONS/SIDE EFFECTS

GI:Hepatic Failure, hepatotoxicity (overdose) GU:renal failure (high doses)


HEMAT: neutropenia, pancytopenis, leukopenia. DERM: rash, urticaria.

INTERACTIONS

Drug to drug: Chronic high-dose acetaminopehen ( 2g/day) may increase


the risk of bleeding with warfarin. Heptotoxicity is additive with other
hepatotoxic substances, including alcohol. Concurrent use of
sulfinpyrazone, isoniazid ,rifampin, phenytoin, barbiturates and
carbamazepine may increase the risk of acetaminophen-induced liver
damage. Concurrent NSAIDs increase the risk of adverse renal effects.
Proprnolol decrease metabolism and may increase effects.

NURSING IMPLICATIONS OF DRUG ADMINISTRATION

Assessment
•Obtain complete health history, incuding allergies, alcohol use and drug
history for possible drug interactions. Patients who are malnourished or
chronically abuse alcohol are at higher rish of developing
hepatotoxicity.

•assess prolonged use of acetaminophen increases the risk of adverse


renal effects. Combined doses of acetaminophen and salicylates
should not exceed the recommended dose of eithe drug given alone.

•Pain: assess type, location and intensity prior to and 30-60 min following
administration.

•Fever: assess fever, note presence of associated signs (diaphoresis,


tachucardia and malaise).

•Lab Test Considerations: Evaluate hepatic,and renal function


periodically during prolonged theraphy.

•May alter results of blood glucose monitoring. May cause decreased


values.

•Toxicity and Overdose: If overdose occurs, acetylcysteine (Acetadote)


is the antidote.

Potential Nursing Diagnoses

•Acute pain

•Risk for imbalanced bodly temperatures

Implementation

•When combinedk with opiods do not exceed the maximum


recommended daily dose of acetaminophen.

•PO: administer with a full glass of water.

•May be taken with food or on an empty stomach.

Patient Teaching

•Advise patient to take exactlly as directed. Chronic use of 4g/day (2g in


alcoholics) may lead to hepatotoxcity, renal or cardias camage. Adults
should not take longer then 10 days and children no longer than 5
days. Short -term doses with sallicylates or NSAIDs should not exceed
recommended daily dose of either drug alone.

•Advise patient to avoid alcohol.

•Caution patients to check lablels on all OTC products. Advise patients to


avoid taking more than one product containing acetaminophen to
avoid toxicity.
•Advise patient to report if discomfort or fever is not relieved by routine
doses or if fever is greater than 39.5 or last longer than 3 days.

•Inform patients with diabetes that acetaminophen may alter blood sugar
results.

Evaluation

•Relief of mild pain

•Reduction in fever

You might also like