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Adrenaline

This document provides the neonatal medication protocol for adrenaline at the Neonatology Clinical Care Unit of King Edward Memorial Hospital and Princess Margaret Hospital. It outlines the drug presentation, actions, indications, dosages, preparation, administration, adverse effects, and references for adrenaline use in neonates. Adrenaline is a sympathomimetic agent used for cardiac arrest, severe bradycardia, acute hypotension, bronchospasm, and low cardiac output. Intravenous, endotracheal, and nebulized routes are described. Side effects include tachycardia, dysrhythmias, hypertension, and tremors.

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1K views2 pages

Adrenaline

This document provides the neonatal medication protocol for adrenaline at the Neonatology Clinical Care Unit of King Edward Memorial Hospital and Princess Margaret Hospital. It outlines the drug presentation, actions, indications, dosages, preparation, administration, adverse effects, and references for adrenaline use in neonates. Adrenaline is a sympathomimetic agent used for cardiac arrest, severe bradycardia, acute hypotension, bronchospasm, and low cardiac output. Intravenous, endotracheal, and nebulized routes are described. Side effects include tachycardia, dysrhythmias, hypertension, and tremors.

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razvan032006
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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  • Neonatal Medication Protocol: Adrenaline

WOMEN AND NEWBORN HEALTH SERVICE

Neonatology Clinical Care Unit (NCCU)


King Edward Memorial Hospital & Princess Margaret Hospital

NEONATAL MEDICATION PROTOCOLS


ADRENALINE NCCU Clinical Guidelines
Created by: NCCU KEMH/PMH
Date for review: Aug 2016 Perth, Western Australia

DRUG: ADRENALINE
PRESENTATION: Ampoule: 1 in 10,000, (1mg/10mL) 10mL
Ampoule: 1 in 1,000, (1mg/mL) 1mL
Respirator Solution : 1% 15mL
ACTION & Sympathomimetic agent
INDICATION: For cardiac arrest, severe bradycardia, acute hypotension,
bronchospasm.
Low cardiac output
DOSE: Intravenous:
USE 1 IN 10,000 AMPOULE ONLY
0.1 - 0.3mL/kg/dose

Intravenous infusion:
USE 1 in 1000 AMPOULE ONLY
To be further diluted (see Preparation section)
Initially 0.1microgram/kg/minute, increasing to a maximum of
1microgram/kg/min

Endotracheal tube:
USE 1 IN 10,000 AMPOULE ONLY
0.1 – 0.3mL/kg/dose
For ease of calculation in an acute resuscitation a dose of 1mL may
be given in a term infant and 0.5mL in a preterm infant. Repeated
doses may be required.

Nebulisation:
Using Respirator Solution
0.05mL/kg/dose
Using 1 in 1000 ampoule only
0.5mL/kg/dose
Dilute to 2-4mL with saline.
PREPARATION: Use solution prepared in Pharmacy if available.
To give a dose of 0.1 microgram/kg/min when infused at 1mL/hr:
Take 0.3mg of adrenaline (ie 0.3mL of 1:1000) per kilogram of baby’s
weight and dilute to 50mL with glucose or glucose / saline solutions.
If a different concentration is required, refer to the Calculation of Drug
Infusion table.
Page 1 of 2
This document should be read in conjunction with the NCCU Disclaimer.
ADMINISTRATION: Intravenous injection
Intravenous infusion
Umbilical arterial/venous injection
Nebulisation
ADVERSE Tachycardia, dysrhythmias, hypertension, tremor, cold extremities,
EFFECTS: agitation.
COMMENTS: Incompatible with sodium bicarbonate
If possible correct acidosis prior to adrenaline administration
REFERENCES: NNF 6th Ed 2011
Neofax 2012
Neonatal Pharmacopoeia 2nd Ed 2005 Royal Women’s Hospital;
Melbourne
DATE: August 2013

NEONATAL MEDICATION PROTOCOL: ADRENALINE Date for review: Aug 2016


Page 2 of 2
This document should be read in conjunction with the NCCU Disclaimer

Page 1 of 2 This document should be read in conjunction with the NCCU Disclaimer. WOMEN AND NEWBORN HEALTH SERVIC
NEONATAL MEDICATION PROTOCOL: ADRENALINE Date for review: Aug 2016 Page 2 of 2 This document should be read

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