Name of
Medications
Classifications Pharmacodynamics Indications Containdications Ad
Generic
or
(Brand Name)
Mode of Action
1. Nalbuphine Pharmacologic Analgesia is believed It is used for: Contraindicated in
Hydrochloride classification: to result from action patients
(Nubain) narcotic agonist- of drug at opiate Moderate to hypersensitive to
severe pain
antagonist, opioid receptor sites in the drug. Use cautiously
Supplement to
partial agonist CNS, relieving in patients with
anesthesia
moderate to severe history of drug abuse,
Therapeutic pain. The narcotic emotional instability,
classification: antagonist effect may head injury,
analgesic, adjunct result from increased intracranial
to anesthesia competitive inhibition pressure, impaired
at opiate receptors. ventilation, MI
Like other opioids, accompanied by
nalbuphine causes nausea and vomiting,
respiratory upcoming biliary
depression, sedation, surgery, hepatic or
and miosis. In patients renal disease, and in
with coronary artery patients with a sulfite
disease or MI, it sensitivity.
appears to produce no
substantial changes in
heart rate, pulmonary
artery or wedge
pressure, left
ventricular end-
diastolic pressure,
pulmonary vascular
resistance, or cardiac
index.
2. Bisacodyl Pharmacologic Bisacodyl has a direct It is used for: Contraindicated in
(Correctol, classification: stimulant effect on the patients
Dulcolax, Fleet diphenylmethane colon, increasing Constipation, hypersensitive to
Laxative, derivative peristalsis and preparation drug; in patients with
for childbirth,
Modane) enhancing bowel abdominal pain,
Therapeutic surgery, or
evacuation. nausea, vomiting, or
classification: rectal or other symptoms of
stimulant laxative bowel appendicitis or acute
examination
surgical abdomen;
and in patients with
rectal bleeding,
gastroenteritis, or
intestinal
obstruction.
3. Oxytocin Pharmacologic Oxytocin increases the It is used for: Contraindicated in
classification: sodium permeability patients
(Pitocin, exogenous of uterine myofibrils, Induction of hypersensitive to
Syntocinon) labor
hormone indirectly stimulating drug and in those
Augmentation
the contraction of with severe toxemia,
Therapeutic of labor
uterine smooth hypertonic uterine
classification: Reduction of
muscle. The threshold patterns, total
oxytocic, lactation postpartum
for response is placenta previa, and
stimulant bleeding after
lowered when vasoprevia. Also
expulsion of
estrogen levels are contraindicated when
placenta
high. Uterine response To induce cephalopelvic
increases with the abortion disproportion is
length of the Oxytocin present; when
pregnancy and challenge test delivery requires
increases further conversion, as in
to assess fetal
during active labor. distress in transverse lie; in fetal
Response mimics high-risk distress when
labor contractions. pregnancies of delivery isn’t
greater than imminent; and in
31 weeks’ prematurity and
gestation other obstetric
emergencies.
4. Cefuroxime Pharmacologic Cefuroxime is It is used for: Contraindicated in
axetil classification: primarily bactericidal; patients
second-generation it also may be Serious lower hypersensitive to
(Ceftin) respiratory,
cephalosporin bacteriostatic. Activity cefuroxime or other
depends on the urinary tract, cephalosporins. Use
Therapeutic skin, and skin-
organism, tissue cautiously in breast-
Cefuroxime classification: penetration, dosage, structure feeding women and
sodium antibiotic infections;
and rate of organism in patients with
bone and joint
multiplication. It acts impaired renal
(Kefurox, infections;
by adhering to function or penicillin
Zinacef) septicemia;
bacterial penicillin- allergy.
binding proteins, meningitis
thereby inhibiting cell caused by
wall synthesis. susceptible
organisms.
Pharyngitis,
tonsillitis,
lower
respiratory
tract infection,
urinary tract
infection
Otitis media,
impetigo
Perioperative
prophylaxis
Gonorrhea
(urethral,
endocervical,
rectal)
Lyme disease
(erythema
migrans)
5. Ibuprofen Pharmacologic Mechanisms of action It is used for: Contraindicated in
classification: are unknown; patients
(Advil, NSAID ibuprofen is thought Arthritis, gout, hypersensitive to
Children’s and
to inhibit drug or in those who
Advil, Therapeutic prostaglandin postextrac- have the syndrome of
Medipren, classification: tion dental
synthesis. nasal polyps,
Motrin, nonnarcotic pain angioedema, and
Primary
MotrinIB, analgesic, bronchospastic
Nuprin, antipyretic, anti- dysmeno-
reaction to aspirin or
Pediacare inflammatory rrhea
other NSAIDs.
Fever, Rufen, Mild to
Contraindicated
Trendar) moderate
during the last
pain,
trimester of
headache,
pregnancy because it
backache and
may cause problems
minor aches
with the fetus or
associated
complications during
with the
delivery.
common cold
Juvenile Use cautiously in
arthritis patients with
Fever
impaired renal or
reduction
hepatic function, GI
disorders, peptic
ulcer disease, cardiac
decompensation,
hypertension, or
coagulation defects.
Because chewable
tablets contain
aspartame, use
cautiously in patients
with
phenylketonuria.
6. Terraferron Vitamins and Terraferron works by It is used for: Contraindicated in
minerals completing the need patients with a
Ferrous of iron in the body; Improving the known
sulfate; folic Antianemics acting on nutritional hypersensitivity to
acid; vitamin status of
megaloblastic bone any of the
B-complex; marrow to produce a patient with ingredients.
Vitamin C; iron deficiency
normoblastic marrow. Hemochromatosis
Nicotinamide 1 For the
and hemosiderosis
capsule prevention
are contraindications
and treatment
to iron therapy.
of anemias
due to folic
acid and
vitamin B12
deficiencies,
also from
nutritional
deficiency of
vitamin B
complex.
