Name: Nicholas M.
Tagle NCM-RLE
Year & Section: BSN IV-A
Drug Study: Metoclopramide
Generic Name Indication Mechanism of Action Classification Side Effects/Adverse Nursing Responsibilities
Drug Reactions
Generic Name
Metoclopramide -relief of symptoms Stimulates motility of Dopaminergic - Allergy to Before
of acute and Upper GI tract blocker metoclopramide - Observe 15 rights in drug
Trade Name recurrent diabetic without stimulating -GI hemorrhage administration.
Reglan, gastroparesis gastric, billiary, or -Mechanical - Assess for allergy to
Maxolon pancreatic secretions; obstruction or metoclopramide.
Dosages -Short-term appears to sensitize perforation - Assess for other contraindications.
therapy for adults tissues to action of -Pheochromocytoma - Keep diphenhydramine injection
10-15 mg PO with symptomatic acetylcholine; relaxes -Epilepsy Precaution readily available in case
up to 4 GERD who fail to pyloric sphincter, -Previously detected extrapyramidal reactions occur (50
times/day 30 respond to which, when breast cancer mg IM).
minutes before conventional combined with effects -Lactation - Have phentolamine readily
each meal and therapy on motility, -Pregnancy available in case of hypertensive
at bedtime for accelerates gastric -Fluid overload crisis.
2-8 weeks -Prevention of emptying and -Renal impairment During
Routes of nausea and intestinal transit; little - Monitor BP carefully during IV
Administration vomiting effect on gallbladder CNS: administration.
associated with or colon motility; drowsiness, fatigue, - Monitor for extrapyramidal
Oral emetogenic cancer increases lower lassitude, insomnia, reactions, and consult physician if
Intramuscular chemotherapy esophageal sphincter extrapyramidal they occur.
Intravenous pressure; has sedative reactions, parkinsonism - Monitor diabetic patients.
- Prophylaxis of properties; induces reactions, akathisia, - Give direct IV doses slowly over 1
postoperative release of prolactin dystonia, myoclonus, -2 minutes.
nausea and dizziness, anxiety - For IV infusion, give over at least 15
vomiting when CV: Transient minutes.
nasogastric suction hypertension After
is undesirable GI: Nausea, diarrhea - Dispose of used materials properly.
- Educate patient about side effects.
-Facilitation of - Instruct to report involuntary
small bowel movement of the face, eyes, or
intubation when limbs, severe depression, severe
tube does not pass diarrhea.
the pylorus with - Instruct patient to take drug
conventional exactly as prescribed.
maneuvers - Instruct not to use alcohol, sleep
remedies or sedatives; serious
-Stimulation of sedation could occur.
gastric emptying - Do proper documentation.
and intestinal
transit of barium
when delayed
emptying
interferes with
radiologic
examination of the
stomach or small
intestine
-Unlabeled uses:
Improvement of
lactation;
treatment of
nausea and
vomiting of a
variety of
etiologies:
hyperemesis
gravidarum, gastric
ulcer, anorexia
nervosa