DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Erythropoietin 4,000 IU Antianemics Anemia Contraindicat Responsible CNS: Monitor BP
(Epoietin Alfa) ,SQ every caused by ed in patient for red blood asthenia before therapy.
after chronic renal hypersensitivi cell maturation dizziness, Blood pressure
Hemodialy failure ty to products in the bone fatigue, may increase
sis derived from marrow. headache, especially when
mammal paresthesia, hematocrit
cells or seizures. increases in the
albumin CV: edema, early part of the
(human) and hypertension, therapy.
in those with increased Monitor blood
uncontrolled clotting of counts.
hypertension. arteriovenous Patient may
grafts need
GI: vitamin B12 and
abdominal folic acid.
pain, consti-
pation,
nausea
vomiting
Musculoskele
tal: arthralgia
Respiratory:
cough,
shortness of
breath Skin:
infection site
reactions
rash,
urticarial
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Levofloxacin 500 mg ½ Antiinfective Bacterial Hypersensitiv Inhibits CNS: Observe the 12
(Levox) tablet, OD Fluoroquinolo infection like ity to drug, its bacterial cell seizures GI: rights in giving
ne pneumonia components, wall synthesis medications.
or Pseudomem- Closely monitor
otherquino- branous with renal
lones colitis insufficiency.
Hematologic:
lympocytope Watch for hyper
nia sensitivity
Metabolic: reaction, discon-
Hypoglyce- tinue if rash or
mia other signs and
symptoms occur.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Clonidine 75 mcg, 1 Centrally- Management Hypersensitiv Stimulates Local skin Assess blood
(Catapress) tablet, SL acting drugs of all grades ity to Central alpha- irritation, pressure and
PRN for of clonidine, adrenergic allergic apical pulse
SBP more hypertension sick sinus receptors to contact before initial
than syndrome inhibit dermatitis, dose. If systolic
160mmHg sympathetic hypopigment blood pressure is
cardio ation and <90mmhg or
accelerator hyperpigmen pulse is<60 bpm,
and - withhold drug and
vasoconstrictor tation of the notify physician.
centers. skin. Check for edema
in feet, legs daily.
Constipation, Monitor input-
depression, output ratio:
anxiety, check for
fatigue, decreasing
nausea, output.
anorexia, Note allergic
parotid pain, reactions: fever,
sleep rash, pruritus,
disturban- urticaria,
ces, andioedema
impotence,
urinary
retention,
itching
sensation of
the eye.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Piperacillin + 4.5 gms, Antibiotics Systemic History of Piperacillin, a Nausea & Observe the 12
Tazobactam IV drip &/or local hypersensitivi broad Vomiting, rights in giving
(Tazovex) then ½ lower resp, ty to spectrum, rash, medications.
vial every intra- penicillins against many erthyma. Do skin testing
6 hours abdominal, &/or Gram-positive Dyspepsia, before giving the
skin & skin cephalospori and Gram- Insomnia, medication and
structure, ns or β- nega-tive headache, let the physician
gynecological lactamase aerobic and fever confirm its result
, bone & joint inhibitors. anaerobic bac- agitation, after 30 minutes.
infections; teria, exerts pruritus. Obtain history of
UTI bactericidal hypersensitivity to
(complicated activity by antibiotics.
& inhibition of Monitor patient
uncomplicate both septum carefully during
d), bacterial and cell wall the 30 minutes
septicemia & synthesis. The after initiation of
infections in presence of the infusion for
neutropenic tazobactam in signs of hypers-
patients. the piperacillin ensitivity.
and tazobac- Instruct the
tam for injec- patient to report
tion formula- rash, itching, or
tion enhances other signs of
and extends hypersensitivity .
the antibiotic Advice the patient
spectrum of pi- to report loose
peracillin to stools or diarrhea
include many as these may
β-lactamase indicate
pro-ducing pseudomembran
bacteria nor- ous colitis.
mally resistant.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Amlodipine 10 mg, 1 Calcium Treatment of Hypersensitiv A calcium CV: Monitor BP for
(Norvasc) tablet, Channel mild to ity to channel palpitations, therapeutic
BID Blocker moderate Amlodipine blocking agent flushing, effectiveness. BP
hypertension that selectively tachycardia, reduction is
and angina blocks calcium peripheral or greatest after
ion reflux facial edema, peak level of
against cell bradycardia, amlodipine is
membranes of chest pain, achieved 6 to 9
cardiac and syncope, hours following
vascular postural oral doses.
smooth muscle hypotension
without CNS: Monitor for S&S
changing headache, of dose-related
serum calcium dizziness, peripheral or
concentrations fatigue facial edema that
. It predomi- GI: gingival may not be
nantly acts on hyperplasia accompanied by
the peripheral weight gain
vascular
resistance, Monitor more
and increases frequently when
cardiac output. additional
antihypertensive
or diuretics are
added.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Irbesartan 300 mg, I Anti- For the Pregnancy Inhibits the CNS: fatigue, Monitor patient’s
(Aprovel) tablet, OD hypertensive treatment of and lactation vasoconstrictin anxiety, BP regularly.
hypertension g and dizziness, Monitor patient’s
and aldosterone- headache electrolytes.
treatment of secreting CV: chest Assess patient’s
renal disease effects of pain, edema, and family’s
in patients angiotensin II tachycardia knowledge of
with by selectively EENT: drug therapy.
hypertension blocking. pharyngitis, Inform patient
and type II rhinitis, sinus that drug may be
diabetes abnormality, taken once daily
mellitus, as GI: UTI with or without
part of an Metabolic: food.
antihypertens hyperkalemia Instruct client to
ive drug Musculoskele avoid driving and
regimen. tal: hazardous
musculoskele activities until
tal trauma or CNS effects of
pain. drug are known.
Respiratory:
URTI
Skin : rashes
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Acts by directly
Trimetazidine 35 mg, 1 Anti-anginal Long MAOI’s counteracting Rare cases Observe the
(Vastarel MR) tablet, BID drug treatment of (monoamine all the major of GI rights in giving
coronary oxidase metabolic disorders. medications.
insufficiency, inhibitors) disorders Use cautiously in
angina occur-ring patients with
pectoris. within the heart failure or
ischemic cell. hypertension and
The actions of in elderly
trimetazidine patients.
include limita-
tion of intracel-
lular acidosis,
correction of
disturbances
of transmem-
brane ion
exchanges
and prevention
of excessive
production of
free radicals.
Decrease
myocardial
oxygen
requirement by
decreasing the
heart rate,
ventricular
volume, blood
pressure and
contractility.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Isosorbide 60 mg, 1 Anti-anginal Prevention The Nitrates are CNS: Instruct patient to
Mononitrate tablet, OD drugs and presence of drugs that act Headache, take medication as
(Imdur) treatment of any allergies directly on the dizziness, directed, even if
Angina to nitrates. smooth muscle and feeling better.
Pectoris in These drugs to cause myasthenia Take missed doses
adults are also relaxation and GI: nausea, as soon as
contraindicat to depress vomiting, and remembered; daily
ed in the muscle tone. incontinence doses of isosorbide
following CV: mononitrate should
conditions. Hypotension be taken 7 rs apart.
Severe Skin: Do not double
anemia, head Flushing, doses. Do not
trauma or pallor, discontinue
haemorrhage sweating and abruptly.
, pregnancy increased Caution patient to
and lactation. perspiration make position
changes slowly to
minimize
orthostatic
hypotension.
DOSAGE/
ROUTE/ CLASSIFI- CONTRA- MECHANISM ADVERSE NURSING
DRUG NAME INDICATION
FREQUE CATION INDICATION OF ACTION REACTION RESPONSIBILITIES
NCY
Ivabradin HCl 5 mg, 1 Anti-anginal Symptomatic Hypersensitiv Ivabradine is a Cardiovascul Monitor BP and
(Coralan) tab, OD treatment of ity, blood pure heart ar: pulse before
chronic pressure is rate- lowering bradycardia therapy, during
stable angina <90 mmHg; agent, acting palpitations, dosage titration,
pectoris in sick sinus by selective supraventri- and periodically
coronary syndrome and specific cular extra- throughout
artery, inhibition of the systoles therapy.
disease cardiac GI: nausea, Assess for signs
patients with pacemaker. constipation of CHF
normal sinus The cardiac (peripheral
rhythm. effects are edema, crackles,
specific to the dyspnea,weight
sinus node gain, jugular
with no effect venous distention
on intra-atrial, Angina: Assess
atrioventricular location, dura-
or intraven- tion,Intensity and
tricular precipitating
conduction factors of pa-
times, nor on tient’s anginal
myocardial pain.
contractility or Hypertension:
ventricular Check frequency
repolarization. of refills to moni-
tor adherence.
Monitor serum
potassium perio-
dically. Hypoka-
lemia increases
the risk of ar-
rhythmias
