BIO 230 Course Learning Objectives
BIO 230 Course Learning Objectives
This class will ask you to evaluate, synthesize, analyze, apply and comprehend the
course material. Memory only will not allow you to pass this class!
Lecture Learning Objectives for BIO 230
Note: Use these study guides as a general resource for course material. As the semester
continues I may add/delete course objectives to these study guides. I will make
announcements of these changes in class or on Blackboard. It is your responsibility to
attend class and take notes during lecture of all material covered. Some areas may be
assigned as independent reading/learning but I will always be available to help you
understand any content that is challenging or confusing.
1. Define the following terms: microscopic anatomy: cytology vs. histology; gross
anatomy: surface anatomy, regional anatomy vs. systemic anatomy; homeostasis.
2. Describe the levels of organization.
3. Use directional terminology to describe the relative position of the body parts.
4. Define and learn each of the anatomical regions and landmarks of the body.
5. Describe the plans of division used to divide and image the body.
6. Learn the terminology used in sectional anatomy.
7. Describe the location of the various body cavities. Identify the major organ(s)
contained within each cavity and the affiliated serous membranes.
8. Understand the function of serous membranes found in the ventral body cavities.
How are they named? What are their names and which organs do they cover?
9. Memorize the nine abdomino-pelvic regions and describe their relative locations
using anatomical and directional terminology.
10. Learn how to recognize structures that have been cut via cross section vs.
longitudinal section.
11. Understand how 2D histology slides can represent a 3D tissue depending on the
type of cut used in histological preps.
12. Learn the difference between a cross-sectional cut and a longitudinal cut.
1. Name the three primary germ layers of the embryo and those tissues each layer
give rise to. Include the origins of connective tissue and the development of organ
systems. (Embryology Summary: pgs: 82, 84-86)
2. Name the four main tissue types of the body and the functions they serve.
3. Learn the functions and classifications of connective tissue. We will learn the
other tissues later.
4. Describe the structural characteristics and organization of connective tissue
(scattered cells, extracellular matrix, vascularity, presence of extracellular fibers,
variety of cell types, etc).
5. Define the following terms associated with connective tissue: matrix, ground
substance, organic fibers (all three types), cell types, mesenchyme.
6. Describe the six main types of connective tissue and the cells associated with each
type.
7. Know the different ground substance and proteins fibers associated with each type
of connective tissue. How does the change in these factors influence the
characteristic of the connective tissue
8. Understand the structure, function, and location for each kind of connective tissue.
9. Understand the similarities and differences between the six different types of
connective tissues.
10. Describe the basic structure of cartilage as well as the differences between hyaline,
fibro-, and elastic cartilage. Describe their respective functions and locations.
11. Compare and contrast between the structures of bone vs. cartilage both of which
are connective tissue.
12. Understand the mechanism behind cartilage growth (Appositional and Intersitital)
and the cells involved in each process.
13. Understand the difference between the perichondrium and periosteum. What cells
are associated with each membrane? How many layers compose each membrane.
1. List the multiple function of the integumentary system and describe the specific
anatomical structures responsible for each function.
2. Describe the structural organization, tissue type and function of the 2 main layers
of skin (epidermis and dermis) and their various sublayers including the 5 strata
of the epidermis (basale/germinativum, spinosum, granulosum, lucidum,
corneum) and the 2 sublayers of the dermis (papillary, reticular).
3. Explain the differences between thick and thin skin including both structural
differences and location
4. Define epidermal ridges and lines of cleavage in the dermis and discuss their
clinical significance.
5. Describe the microscopic structures (tissue types and accessory structures) and
function of the subcutaneous layer located deep to skin, called the
hypodermis/superficial fascia.
6. Explain the difference between keratinocytes and melanocytes, including their
respective functions and locations.
7. Describe the process of desquamation of dead, keratinized cells and the
replacement of those cells by mitosis. Where does each of these processes occur
(in which statum?) and what happens in the intervening strata to the cells? How
long does this process generally take?
8. Describe the 3 different factors that cause pigmentation of skin. Which of these
factors allows human skin color to vary widely between pinkish-white to dark-
brown in human populations? What ultimately determines ones’ skin color and
what cellular processes are involved?
9. Describe the blood supply to the skin (both plexuses).
10. Describe the structure, function, location of the accessory structures of skin,
including: arrector pili, hair follicle, sebaceous gland, sweat gland, tactile
(Meissner’s) corpuscle, lamellated (Pacinian) corpuscle.
11. Contrast the method of secretion for the 2 types of glands (apocrine and
merocrine).
1. Describe the structure of compact/dense bone tissue. Define all new terminology,
including but not limited to: periosteum, osteon, central canal, concentric
lamellae, lacunae, canaliculus, interstitial lamellae, circumferential lamellae,
perforating canal.
2. Describe the structure of spongy/cancellous/trabecular bone tissue. Define all new
terminology, including but not limited to: trabeculae, lamellae, endosteum.
3. Differentiate the following cell types by function: osteoprogenitor, osteoblasts,
osteocytes, and osteoclasts. Where are each located?
4. Describe the structural and functional difference between the periosteum and
endosteum. What cells are involved with each?
5. Define the axial vs. the appendicular skeleton.
6. Describe the 6 different classes of bones by shape. Give examples of each class of
bone and describe their location in the skeleton (use regional terminology and
axial vs. appendicular location terms).
7. Describe the gross and microscopic anatomy of a long bone.
8. Discuss the location of spongy bone tissue vs. compact bone tissue, red vs. yellow
bone marrow and medullary cavity (found in cancellous bone).
9. Understand the basic terminology of both internal and external gross anatomy.
10. Locate and structurally differentiate between the endosteum vs. periosteum.
11. Understand the difference between the epiphyseal plate vs. epiphyseal line. What
tissue makes up the epiphyseal plate?
12. Describe the two methods of bone development, Intramembraneous vs.
Endochondral. Make note of the mechanism of each method of bone development
13. Differentiate between bone growth and bone development.
14. Which bones use Intramembranous development and which bones use
endochondral development?
15. Understand the difference between ossification and calcification.
16. Discuss the mechanism of bone elongation at the epiphyseal plate vs. that of bone
width growth (appositional).
17. Identify the role that cartilage plays during bone growth and development.
18. Know the difference between epiphyseal cartilage vs. articular cartilage. What
type of cartilage are these?
19. What nutrient factors are required for normal bone growth throughout life?
20. What hormones are required for normal bone growth? What are their functions?
21. Describe the function and relative location of dense vs. cancellous bone in a long
bone, its reason for being there, and how this contributes to bone strength,
remodeling and growth.
22. Discuss the difference between red vs. yellow bone marrow.
23. Learn the difference between bone remodeling, bone growth and bone
development. These are three different processes with different cellular
mechanisms.
24. What factors trigger bone remodeling throughout our lives?
25. Discuss bone repair after a fracture. What cells are involved and what role do they
play?
26. Learn the four steps to bone repair
Articulations
Chapter 8: pgs. 212 – 226, 228 – 233
1. Name and describe the 3 classes of joints found in the human body according to
the structural classification (bony, fibrous, cartilaginous, synovial).
2. What criterion is used to classify joints structurally?
3. Name and define the 3 functional classes of joints (synarthrosis, amphiarthrosis,
diarthrosis) and give an example of each.
4. Define the following terms and give an example of each: suture, syndesmosis,
gomphosis, synchondrosis, symphysis, synostosis.
5. Draw and label the distinguishing features of a simple synovial joint.
6. Differentiate and describe the various features in terms of their structure/histology,
function, and location: joint/articular capsule, synovial membrane, synovial/joint
cavity, synovial fluid, and articular cartilage.
7. Understand the 3 functions synovial fluid serves.
8. List and describe the structure including histology and function of all possible
accessory structures that may be found associated with a given synovial joints:
bursae, synovial tendon sheaths, menisci and articular discs, fat pads, ligaments,
and tendons.
9. Describe the four factors that contribute to the stability/strength of a synovial joint
and give an example of a joint that is primarily stabilized by each factor.
10. What attribute is gained at the expense of stability and strength in synovial joints?
11. Learn the bones, bone markings, and ligaments that make up the following 5
joints: Temporomandibular, Glenohumeral joint, Elbow joint, Hip joint, Knee
joint. What classification do these joints fall under?
12. Distinguish the following 6 different structural classifications of synovial joints:
plane, hinge, pivot, condylar/ellipsoidal, saddle, and ball-and-socket joints.
13. Cite an example of a joint for each of the six structural classification of synovial
joints.
14. Describe the types of movement allowed and cite an example located in the
human body for each six types.
15. Distinguish the 4 following types of articular motion: gliding, angular,
circumduction, and rotation.
16. Define the following terms listed below and used to describe movement at a
synovial joint:
a. Gliding: gliding
b. Angular: flexion, extension, hyperextension, abduction, adduction,
circumduction
c. Rotation: internal/medial, external/lateral, pronation, supination
d. Special: inversion, eversion, dorsiflexion (ankle flexion), plantar flexion
(ankle extension), protraction, retraction, elevation, depression,
opposition.
1. Compare and contrast the 3 types of muscle tissue (skeletal, cardiac, smooth).
Include information on their respective locations, functions, histological
organization (striations, nuclei, cell shape, branching), repair abilities, and
innervation.
2. Describe the characteristics and functions of skeletal muscle tissue.
3. Draw and label the gross anatomy of a skeletal muscle. Define each of the
following terms: origin, insertion, belly, epimysium, perimysium, fascicle,
endomysium, fiber, tendon, aponeurosis.
4. Describe the internal/cellular organization of skeletal muscle fibers (myofibers).
Include in your description: myofiber, sarcoplasm, sarcolemma, sarcoplasmic
reticulum, transverse tubules, triad, myofibril, myofilament. Which of these are
new organelles, unique to muscle cells? Define the functional role of each of the
listed cellular organelles/structures?
5. Consider the microanatomy of a myofiber and define the components of a
sarcomere. Identify the following structures, including the molecular components
and their function, in muscle contraction: Actin, myosin, Z-line, I band, M-line, H
band, and A band.
6. Explain how the molecular organization of a sarcomere relates to the striations
(dark vs. light bands) evident in histological sections of skeletal muscle tissue.
7. Explain how the structure of a sarcomere changes during a muscle contraction.
What happens to the A-bands as opposed to the I-bands during a contraction?
8. Define a neuromuscular junction (synapse). Identify its structures, including:
synaptic terminal, synaptic vesicles, acetylcholine, actetylcholine esterase,
synaptic cleft, motor end plate.
9. Define and describe a motor unit. Given the number of myofibers located in a
muscle and the number of motor neurons innervating that muscle, be able to
understand how the number of activated motor units correlates with the work of a
muscle.
10. What is muscle tone and how is it maintained? What receptors are involved?
What functions does muscle tone serve the body?
11. Compare and contrast structural and functional characteristics of fast (twitch) vs.
slow (twitch) muscle fibers. You may ignore the intermediate fiber.
1. Describe neural tissue, its properties and the main cell types involved.
2. Make a running list of new vocabulary associated with the nervous system.
Attempt to define the words in terms of structure, function, location and/or
example (where appropriate). Use Table 13.1 as a reference, although we will not
be covering all these terms.
3. Understand and explain the structural and functional subdivisions of the nervous
system. Define the following terms: afferent, efferent, receptor, sensory, motor,
effectors, somatic autonomic, and visceral.
4. Draw a chemical synapse (vesicular synapse) between 2 neurons. Label the
presynaptic membrane, postsynaptic membrane with protein receptors, synaptic
knob/terminal bouton, synaptic cleft, telodendrion, and indicate the location of the
neurotransmitters inside vesicles. Define a neuroeffector junction and give 2
specific examples.
5. Describe the structure of a nerve. How does a tract differ from a nerve? Consider
both structure and location.
6. Describe the structural characteristics of 3 functional types of neurons: sensory,
motor, interneurons (association). List at least 2 specific types of sensory neurons
and 2 specific types of motor neurons and describe their locations (consider
visceral vs. somatic distinctions).
7. What is a neuroglial cell? How do neuroglia differ structurally and functionally
from neurons? Describe the structure, function and location of the 6 types of
neuroglia.
8. What function does myelin serve? Which cells provide myelination in the CNS vs.
the PNS?
9. Draw a cross section and a longitudinal section of a myelinated axon in the PNS.
Label the Schwann cell, neurolemma, nucleus, axon, axolemma, myelin sheath,
and node of Ranvier.
10. Categorize the 3 types of receptors (exteroreceptors, proprioceptors, and
interoceptors), and different types of effectors (skeletal, smooth, and cardiac
muscle, glands, adipose tissue).
11. Trace the process by which a receptor activates a neuronal response, which in turn
coordinates an effector-mediated response.
12. Outline the anatomical organization of the nervous system. Use Figure 13.15 to
guide your study.
13. Describe 3 structural types of neurons: (pseudo)unipolar, bipolar, and multipolar.
Where is each type commonly found in the body and what pathway does it serve?
Possible pathways include sensory (afferent), motor (efferent), and special senses
(afferent)?
1. Describe the gross anatomy of the thoracic cavity, pleural cavity, and pericardial
cavity including the mediastiunum, parietal and visceral pericardia.
2. Identify the layers and tissues composing the layers of the heart, from the
epicardium to the endocardium.
3. Draw a coronal section of the heart and label the four hear chambers, four heart
valves and all the great vessels entering and leaving the heart. Describe the path
of blood flow into the thru the hart. Label the three layers of the wall of the heart.
4. Compare and contrast the atrioventricular valves (AV) and semilunar valves (SL)
in terms of both their structure and their mechanism of function. Are both right
and left AV valves identical in structure? What about both semilunar valves? How
are these four valves named and what is the basis of their individual names?
5. Describe or draw the branching diagram of the coronary circulation. Describe the
location of each vessel on the heart based upon external anatomical landmarks
(anterior vs. posterior interventricular sulci, coronary sulcus, etc).
6. Identify and label the conduction pathways thru the heart. What specialized cell
types makes up this pathway? Where is it located in the heart (layer)?
1. List the specialized tissues and organs of the lymphoid system. Describe the
specific structure and function of each, including the major lymph-collecting
ducts (tonsils, cisterna chili, lymphatic capillaries, lymph fluid, lymph nodules,
thymus, spleen, bone marrow, etc).
2. What is the difference between lymph nodules and lymph nodes? Where are the
following examples of lymph nodules located? (tonsils, Peyers patch of
aggregated lymphoid nodules).
3. Name the 3 major lymphocytes, their site of origin and specific functions.
4. Trace the lymphatic vessel pathways from capillaries to the two lymph ducts.
5. Identify the nine lymphatic trunks and which region of the body they drain.
6. Identify where the two lymph ducts drain lymph back into the venous system.
Respiratory System
Chapter 24: pgs. all
1. Draw the respiratory tract, from external nares to alveoli, and label the organs
and/or macroscopic structures. Briefly describe the function of each organ and
structure in the tract.
2. Describe how the histology of the wall of the respiratory tract changes from one
organ or region to the next. Consider changes in the respiratory epithelium,
cartilage, and smooth muscle layers. You must learn to justify this organization
based upon local functions served by each organ.
3. Describe the respiratory (exchange) membrane where gases are exchanged
between blood in pulmonary capillaries and air inside of lungs. What layers form
this membrane and what tissue type are they? What is lung surfactant and where
is it located and what cell produced it?
4. Describe the Pleural cavities and pleural membranes, and the function they serve
in respiration.
5. Explain ventilation in terms of volume and pressure changes, muscle use and
open-air passageways. Which skeletal muscles are involved?
1. Draw the route that food takes from the mouth to anus. Label all organs and
regions of organs, including landmarks and feature unique to the organ. Add
accessory organs to your drawing and connect them by ducts to the correct organ
of the GI tract. Label all pertinent structures.
2. Draw a cross section of the wall of the GI tract. Label the four main layers
(mucusa, submucosa, muscularis externa, serosa or adventitia), the luman, and
the sublayers of the mucosa (mucosal epithelium, lamina propria, muscularis
mucosa), and of the muscularis externa (inner circular, outer longitundinal layers
(oblique were appropriate). Identify where the location and functional differences
along the GI tract.
3. Consider the four main layers in the wall of the GI tract, one layer at a time.
Describe the basic structure (histology and gross anatomy) of each layer and
explain modification to this basic structure along the entire length of the tract
(organ by organ).
4. Describe the peritoneal cavity, the parietal peritoneum and visceral peritoneum,
and the affiliated membranes: mesentry proper, mesocolon, lesser omentum,
greater omentum, falciform ligament, coronary ligament and ligamentum teres.
What organ do they suspend and where do they arise from: the dorsal body wall
or the ventral?
5. List the mechanical and chemical digestion of food. Where each occurs and how
they modify food. List the specific secretions (by name), and where they are
produced (name cell, structure, organ/gland), where they enter the lumen of the
GI tract, and what effect they have on food.
6. What is the function of the liver? What is bile, where is it produced, where is it
stored, and what is its function?
7. Draw and label the biliary duct system that drains the liver, gallbladder and the
pancreas. Include its point of entry into the luman of the GI tract. Include:
common hepatic duct, cystic duct, common bile duct, pancreatic duct,
hepatopancreatic sphincter.
1. Draw and label the organs of the urinary tract. Describe the specific structure
(including histology) and the function of each organ (kidney, ureter, bladder,
urethra).
2. Describe the gross anatomy of the kidneys, both external features (hilus, renal
capsule, adipose capsule (perinephric or perirenal fat)), and internal features
(renal cortex, renal medulla, renal pyramids, renal papilla, renal columns, minor
calyx, major calyx, renal pelvis).
3. Draw and label the complete nephron. Alongside each labeled structure of the
nephron draw an individual cell representing the type of epithelium that lines that
portion of the renal tubule. Connect the end of the renal tubule to the collecting
system of tubules/ducts that lead to the renal pelvis; be sure to label them.
Describe the specific function of each labeled structure.
4. Describe or draw the pathway that brings blood to the kidneys, into and thru the
cortex and medulla, and back out of the organ to the inferior vena cava. Label all
vessels including peritubular capillaries and vasa recta.
5. Describe or draw the structural components of the juxtaglomerular complex.
What is the function of this structure?
The Reproductive System
Chapter 27: pgs. all
1. Draw and label the male reproductive tract (the pathway that spermatozoa follow
from formation to ejaculation). Describe the specific function of each organ of the
tract.
2. Locate and describe the following terms: dartos muscle, inguinal canal, spermatic
cord, cremaster muscle, tunica albuginea, semiferous tubules, Sertoli cells,
interstitial cells (of Leydig), epididymis, ejaculatory duct, glans penis, prepuce,
urogenital diaphragm, prostatic vs. membranous vs. spongy(penile) urethra.
3. Describe the histology of the scrotum, testis, epididymis, urethra and penis
4. Describe the three accessory glands that produce seminal fluid in the male.
Identify their locations and where it communicates with the tract. List the specific
contribution of each gland to the seminal fluid and the function it serves.
5. Draw and label the female reproductive tract (the pathway that an ovum follows
from formation to release from body). Describe the specific function of each
organ.
6. Locate and describe the following terms:
a. Ovary: primordial follicle, mature/Graafian follicle, corpus luteum,
corpus albicans
b. Uterine tubes: infundibulum, ampulla, isthmus, and fimbriae
c. Uterus: fundus, body, isthmus, cervix, vesicouterine puch, rectouterine
puch, endometrium (functional vs. basilar layer/zone), myometrium,
perimetrium
d. Vagina: fornix and hymen
e. Female external genitalia: vulva (pudendum), labia majora, labia minora,
clitoris, vestibule
7. Describe the histology of each of the following organs: ovary, uterine (Fallopian)
tubes, uterus, vagina.
8. Locate the ligaments/membranes that support the female reproductive tract: broad,
suspensory, ovarian, and round ligaments, and mesovarium.
9. Describe the ovarian cycle and contrast it with the uterine cycle. What structural
changes occur in both the ovaries and uterus during these respective cycles?
Which cycle corresponds with the menstrual cycle? Note: You do not need to
know how hormones play a role in these cycles.
10. Compare and contrast the reproductive organs in the male vs. female. Discuss
their gross anatomy and/or histology as it accommodates function. Compare and
contrast the external genitalia of males vs. female with regards to the structural
deviations during development.
Learning Activities (optional)
These are a list of helpful activities that you can choose to supplement and, hopefully,
enhance your studying. These are optional and will not be graded. These activities do not
cover every chapter but the basic concepts can be applied for learning any content learned
in this class. Only do these if you feel you are learning from them. These are designed to
get you thinking of different ways you can organize your lecture notes and study material.
Find what works best for you and exploit it!
Diagram the following structures and trace the proper nerves through these structures:
1. Dorsal root
2. Dorsal root gangion
3. Ventral root
4. Ventral ramus
5. Dorsal ramus
6. Spinal nerve
7. Gray ramus
8. White ramus
9. Somatic sensory fiber
10. Visceral sensory fiber
11. Visceral motor fiber
12. Postganglionic fiber leading to visceral organs
13. Postganglionic fiber leading to body wall (skin on front and back)
14. Somatic motor nerve
15. Posterior gray horn
16. Lateral gray horn
17. Anterior gray horn
18. Posterior median sulcus
19. Anterior median fissure
20. Sympathetic chain ganglion