LEPR SY
chronic systemic infection
characterized by progressive
cutaneous lesion
Affected organs
Skin
Peripheral nerves
Eyes
Testes
Mucosa of the URT
Causative agent
Mycobacterium leprae
Mode of transmission
Aerosol spread from infected
nasal and oral mucosa
Prolonged skin-to-skin contact
Anesthesia
Fine
Anhidrosis
nerves
Dryness
M. leprae
attacks
Pain then anesthesia
Large
Paralysis
nerves
Atrophy
Diagnosis
Presence of signs and symptoms
+
History of contact with PWL
1 of the 3 signs:
Hypopigmented or reddish patches
with definite loss of sensation
Damaged peripheral nerves
Acid-fast bacilli on SSS
S/Sx
Change in skin color
Loss of sensation on the lesion
Decrease or loss of sweating
Thickened or painful nerves
Muscle weakness
Pain and redness of the eyes
Nasal obstruction or bleeding
Ulcers that do not heal
S/Sx
Madarosis
Lagophthalmos
Clawing of fingers and toes
Sinking of nose bridge
Contractures
Gynecomastia
Chronic ulcers
Pathognomonic sign
The Ridley-Jopling Classification
Multibacillary Paucibacillary
Lepromatous and Tuberculoid and
borderline indeterminate
Infectious type Non-infectious type
(-) Lepromin test (+) Lepromin test
Slow peripheral nerve Rapid peripheral nerve
involvement involvement
5 or more lesions Less than 5 lesions
Modalities of Treatment
MDT
Rehabilitation
Sulfone
therapy
Multidrug Therapy
Use of 2 or more drugs for the treatment
of leprosy
Renders patients non-infectious 1 week
after the initiation of therapy
Rifampicin 600 mg once a month
Dapsone 100 mg daily
Clofazimine 50 mg daily
MB R D C
Multidrug Therapy
Use of 2 or more drugs for the treatment
of leprosy
Renders patients non-infectious 1 week
after the initiation of therapy
Rifampicin 600 mg once a month
Dapsone 100 mg daily
Clofazimine 50 mg daily
PB R D
Nursing Management
Moral support and encouragement
Diet should be wholesome
Terminal disinfection
Prevention and control
Reporting of all cases and suspects
Separating newborn from leprous mothers
BCG vaccination
Adequate nutrition
Health education on the mode of
transmission