Pathophysiology
Predisposing factors: Precipitating factors:
-Hereditary -Hypertension
-Gender: Male -Cardiovascular disease
-Age: -Cigarette smoking
-High cholesterol
-Being overweight
-Heavy Drinking
-Obstructive sleep apnea
-Diabetes Milletus
Narrowing of blood vessels
Formation of plaque deposit
Occlusion of major vessels
Increase pressure in the blood vessels
Due to thrombosis, some neurons die because of lack of oxygen and nutrients
CVA (Stroke)
Cerebral Ischemia
Initiation of ischemic cascade
Anaerobic metabolism of mitochondria, which generates a large amount of lactic acid
Transient Ischemic Attack (weakness of the face, fingers, hands, arms)
Altered Cerebral Metabolism and decrease cerebral perfusion
Damage of the hemisphere of brain
Increased Intracranial pressure
Impaired perfusion and function
-Numbness on the left side of the brain
-Trouble speaking
-Difficulty of walking, dizziness
-Sudden severe headache
If not managed If manage
Space occupying blood clot put more -Pallative care
pressure on the brain tissue -Frequent vital sign and
neuro vital sign
The ruptured cerebral vessels may constrict to
limit blood loss, however, this vasospasm Good cerebral perfusion
will result to further ischemia and necrosis of brain tissue
Good improvement
BRAIN DEATH Good Prognosis