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Medication Doses Table

The document discusses psychiatric comorbidities associated with migraine including panic disorder. It provides recommendations from medical organizations on preventative treatments for migraine and panic disorder, listing several antidepressants, anticonvulsants, and other drugs as options with varying levels of evidence and typical dosages.

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Francisco
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85 views1 page

Medication Doses Table

The document discusses psychiatric comorbidities associated with migraine including panic disorder. It provides recommendations from medical organizations on preventative treatments for migraine and panic disorder, listing several antidepressants, anticonvulsants, and other drugs as options with varying levels of evidence and typical dosages.

Uploaded by

Francisco
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Psychiatric Comorbidities Associated With Migraine 

Episodic Migraine Prophylaxis  Panic Disorder 
American Academy of Neurology and 
American Psychiatric Association (2009) 
American Headache Society (2012) 

Grade A Evidence  Usual Therapeutic  Grade A Evidence  Usual Therapeutic 


(Established Efficacy)  Dose/Day†  (Established Efficacy)  Dose/Day† 
   
β‐blockers    Antidepressants   

Propranolol  40‐240 mg  Citalopram; 


20‐40 mg 
fluoxetine (SSRI) 
Metoprolol  100‐200 mg 
Escitalopram (SSRI)  10‐20 mg 
Timolol  20‐30 mg 
Fluvoxamine (SSRI)  100‐200 mg 
Anticonvulsants    Paroxetine (and 
Paroxetine CR)  20‐40 mg (25‐50 mg) 
Divalproex/valproate  500‐1500 mg  (SSRIs) 
Topiramate  50‐200 mg  Sertraline (SSRI)  100‐200 mg 

Grade B Evidence  Usual Therapeutic  Venlafaxine ER  


150‐225 mg 
(Likely Efficacious)  Dose/Day†  (SNRI) 
  Grade A Evidence 
Usual Therapeutic 
(But With Prescribing 
Antidepressants    Dose/Day† 
Cautions) 
Amitriptyline   
25‐150 mg 
(tricyclic)  Tricyclic 
 
Antidepressants 
Venlafaxine (SNRI)  20‐200 mg 
Imipramine  100‐300 mg 
β‐blockers   
Clomipramine  50‐150 mg 
Atenolol  50‐200 mg 
Benzodiazepines   
Nadolol  80‐240 mg 
Alprazolam  2‐4 mg¶ 
 

  Clonazepam   

   

   

© 2018 American Academy of Neurology Institute  1 
 

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