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Uterine Cancer Pathophysiology Insights

Uterine cancer is more common in older women, Black Americans, and those with genetic predispositions or a history of endometrial hyperplasia or colorectal cancer. Factors like obesity, hormone replacement therapy, lifestyle exposures, and sexual history can increase estrogen levels and suppress hormones that regulate the menstrual cycle, leading to excessive estrogen that promotes uterine cancer development and growth.

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Charlotte Cordero
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454 views1 page

Uterine Cancer Pathophysiology Insights

Uterine cancer is more common in older women, Black Americans, and those with genetic predispositions or a history of endometrial hyperplasia or colorectal cancer. Factors like obesity, hormone replacement therapy, lifestyle exposures, and sexual history can increase estrogen levels and suppress hormones that regulate the menstrual cycle, leading to excessive estrogen that promotes uterine cancer development and growth.

Uploaded by

Charlotte Cordero
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

PATHOPHYSIOLOGY OF UTERINE CANCER

Predisposing Factors:
Precipitating Factors: -Age: over 50 y/o
-Race: Black Americans
Hormone Replacement Therapy Estrogen
-Genetic
-Obesity: increase ESTROGEN -Disease: Endometrial Hyperplasia. Colorectal
-Lifestyle: Exposure to Carcinogens menstruation
-Sexual Activity: nulliparity -Physiologic changes: Early menstruation, Late
menopausal stage, amenorrhea

Excessive Increase estrogen

Suppress LH and FSH

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