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Acetylcysteine Drug Study Overview

Acetylcysteine is a mucolytic agent used as adjunctive therapy for abnormal viscid or thickened mucus secretions associated with conditions like pneumonia, bronchitis, and complications of thoracic or cardiovascular surgery. It works by breaking disulfide bonds in mucoproteins, reducing mucus viscosity. Common side effects include fever, drowsiness, chest tightness, and rhinorrhea. Nursing responsibilities include monitoring for signs of toxicity, obtaining baseline labs, educating the patient on potential adverse reactions, and instructing them on proper administration to maximize effectiveness.

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Mae Ann Bueno Castillon
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442 views2 pages

Acetylcysteine Drug Study Overview

Acetylcysteine is a mucolytic agent used as adjunctive therapy for abnormal viscid or thickened mucus secretions associated with conditions like pneumonia, bronchitis, and complications of thoracic or cardiovascular surgery. It works by breaking disulfide bonds in mucoproteins, reducing mucus viscosity. Common side effects include fever, drowsiness, chest tightness, and rhinorrhea. Nursing responsibilities include monitoring for signs of toxicity, obtaining baseline labs, educating the patient on potential adverse reactions, and instructing them on proper administration to maximize effectiveness.

Uploaded by

Mae Ann Bueno Castillon
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

DRUG STUDY

GENERIC NAME: Acetylcysteine


Brand name: Acetadote, Mucomyst
Drug Classification: Mucolytics

DOSAGE, ROUTE, SIDE EFFECTS and


FREQUENCY (prescribed and INDICATION MECHANISM OF ADVERSE REACTIONS
recommended) ACTION (by system)
Prescribed: Adjunctive therapy for CNS: fever, drowsiness
800 mg abnormal viscid or CV: chest tightness,
thickened mucus tachycardia, edema,
Available forms: secretions in patients flushing
IV injection: 200mg/ml with pneumonia, EENT: rhinorrhea,
Solution: 10%, 20% bronchitis, pharyngitis
bronchiectasis, Respiratory:
complications of bronchospasm, cough,
thoracic surgery or CV dyspnea
surgery Skin: clamminess,
diaphoresis, urticarial
Other: Anaphylactiod
reaction

NURSING RESPONSIBILITIES
CONTRAINDICATION/S (at least 10)
Contraindicated with patients • Monitor cough type and frequency
hypersensitive to drug • Ingestion of more than 150mg/kg of acetaminophen may cause
hepatotoxicity. Measure acetaminophen level 4hours after ingestion to
Use cautiously in elderly or debilitated determine risk of hepatotoxicity
patients with severe respiratory
• Obtain baseline AST, ALT, bilirubin, PT, BUN, creatinine, glucose and
insufficiency
electrolyte levels
• Facial erythema may occur within 30 minutes to 60 minutes of start of
IV infusion and usually resolves without stopping infusion
• When acetaminophen level is below toxic level according to
nomogram, stop therapy
• The vial stopper does not contain natural rubber latex, dry natural
rubber or blends of natural rubber
• Warn patient that drug may have a foul taste or smell that may be
distressing
• For maximum effect, instruct patient to cough or clear his airway
before aerosol administration
• Don’t confuse acetylcysteine with acetylcholine

Patient’s Name / Room No.

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