Acetaminophen Infants & child: 10 -15 mkdose q4-6H Aminophylline ?

3-5mkdose IV load: 6mk

analgesic, >12y.o.:325-650mg q4-6h (20min)
antipyretic MAX: 5 doses/24hr 1-9yo: PO-27mkDay q4-6h IV:1-1.2mkhr
Ad rxn: fetal hepatic necrosis 9-12yo:PO-20mkDay q6h IV:0.9mkhr
(Tx: acetylcysteine) 12-16yo:PO-16mkDay q6h IV:0.7mkhr
(100/ml drp, 120/5,250/5, 325mg,supp:125, 6mo-1yr: 0.6-0.7mkhr
250) 6wks-6mos: 0.5mkhr
Neonate: IV: 0.2mkhr
Acetazolamide Neonates: 25mg/kg/24H BID, TID, or QID 4- Neonatal Apnea:
hydroceph, edema, 7D LD- 5-6mkdose MD- 1-2mkdose q6-8h
epilepsy Children w/ edema: diuresis: 5mg/k/24h Dilute to equal amt with IVF
Ad rxn: metab acidosis, hypoCl, hypoK, Refer: Inc HR, sZ, Hypo/hypertension,
drowsiness, anorexia, muscle weakness vomiting, arrhythmia, feeding intolerance
Prep: IV:500/5ml,PO:125mg, 250mg
Amiodarone Vent arrhythmia/ PSVT
Acetylcysteine 2-5ml TID, QID (infant) Antiarrythmic Class PO: <1yo: 600-800m/BSA/Day BID (X4-14D)
mucolytic 6-10ml TID, QID (child) III >1yo: 10-15/20mkD BID x 10 D 5-
Ad rxn: bronchospasm(give dilator 10-15min 10mkD
b4) Cut all doses in half after 1-4wks of Tx or
(100/5ml syr, 100mg,200mg sachet, 600mg control
tab) IV: LD 5mkd x1hr cont 5-15ug/k/min
nd rd
B10 ml TID, QID Contra: markd sinus brady, 2 & 3 AVblock
Acyclovir >6yo- 800mg 4x/D Prep: 200mg/tab, 150mg/3mL amp
(Varicella, HZV) 2-6yo: 400mg QID VT/VF: 5mkdose rapid IV for pulselessness
>2yo- 200mg QID or 20mkdose QID x5D Perfusing arrhythmias: same dose 20-60min
Max: 800mg/day (200mg, 400mg, 800mg/tab)
Herpex: 200mg/5mL susp

Adenosine Neonate & child: 0.05mkdose push then inc

Paroxysmal SVT bolus doses by 0.05mkdose q2min
antiarrythmic Max: 0.25mk or 12mg
Prep:3mg/ml (2ml)

Albendazole >2y.o 400mg or 10mL susp SD

1-2y.o.: 200mg/tab or 5mL SD
< 2y.o 200 SD Ampicillin- At least 100mkday (based on Ampi)
Prep: 400mg/tab, 4%susp 10mL Sulbactam 100-150(200child)mkD Q6h (mild/mod infxn)
Aminopenicillin 200-300(400child)mkD q6h (meningitic/severe)
(GBS, Listeria, E coli) Adult: 750max q6-8h IV PO: 20-40mkday
Albumin Neonate:0.5- 1g/kg/dose MAX: 1g/k/24hr Adjust dose in renal
colloid Infants & child: 0.5-1g/k/dose Max: 6g Prep: 750(500), 1.5g(1g), 375(250),
failure
Ad rxn: urticaria, fever, circ overload, edema 250/5susp, 375mg, 750mg/tab
Prep: 25%/50cc,100cc, 12.5/50cc
Aldactone 2-3 mkday (od,bid,tid) Amphotericin B 0.3 - 0.7mkd
X saline NB: Initial:0.25-0.5mgK IV Infusion:2-6H
Spironolactone Prep:25mg, 50, 100/tab
solnprecipitate MD:0.5-1mg/kg IvQ24-48H
Ad rxn: hyperK, agranulocytosis, headache
Ampho B 50 mg dilute with 10ml dilute to make
Monitor: CBC, Crea,
U/O, BUN, Crea, Elec a conc of 5mg/ml
Test dose...
Ambroxol 1.2 - 1.6 mkdose eg 2.1kg
10 yo : 1 tab TID or 2tsp x3D1tsp Day 1:0.25/kg
5 - 10 yo: 1/2 tab or 1tsp BID,TID =(wt x0.25)=0.52mg
2 - 5 yo: 1/2 tsp TID (0.52/ 5)= 0.1ml
13 - 24 mos: 1.25 ml drops BID 0.1 ml + 5.2 ml D5water to run for 6h
7 - 12 mos: 1 mlBID Day2: 0.5ml/kg= 1/05mg
< 6 mos: 0.5 ml BID Ampho B 0.21ml + 10.5 ml D5W
Prep: 30mg/tab, 15/5ml, 30/5ml, 6mg/1mL Reconstituted solution =wrapped in aluminum
drops foil to protect from life n store at ref
Infusion line wrapped in aluminum foil
Amikacin 15mkDay q8h MAX: 1.5g/24hr Watch out for apnea, bradycardia, cyanosis
NB:< 29 0-7 18 mkd 48H Be given in AM preferably
8-28 15 mkd 36H Ampicillin 100-150(200)mkD q6h MAX: 500mg q6h
>28 15 mkd 24H GBS, Listeria, E coli MeninG: 200-400 mkd MAX: 12g/24hr
Adjust in RF NB: 50mkdose
30-33 0-7 18 mkd 36H
>7 15 mkd 24H Postnatal Age Interval
>34 ALL 15 mkd 24H <29 0-28 12
Prep: 100mg/2mL, 250mg/2mL, 500mg/2mL >28 8
30-36 0-14 12
>14 8
37-44 0-7 12
>7 8
>45 All 6
 Prep: 250mg, 500mg vial. 250mg, 500mg/cap
125/5mL, 250/5mL, 100/ml drops Benadryl 0.5-1 mkdose(IV) q6h-8h
Amoxicillin 30-50mkDay/ 50-75mkDay H.D 3 - 5 mkday(PO) q6h
Prep: 250, 500mg/cap, 125/5ml, 250/5mL Prep: 25mg.50mg/cap; 12.5/5mL, 50mg/mL
susp, 100/ml drops

Ansimar 10 mkdose BID (6-9) Bisacodyl <2yo 5mg

Prep: 100mg/5mL >2yo 10mg; (5-10mg/tab supp.)
Prep: 5mg/tab; 10mg supp, 10mg/30mL enema
Antamin 0.3 mkdose Bromhexine 0.5-0.85 mkday in 3 doses
Budesonide 1-8 yo= 0.5mg/24 hr OD, BID
Amoxicillin- 20-40mkday PO TID based:Amox Adrenal corticosteroid Max dose 4 doses/ 24 hrs
Anti-infl ammatory
Sulbactam 40-50 mkday IV q8 based:Amox
(Ultramox) 2-6yo: 375 IV Q6/Q8
6-12yo: 750IV Q6/Q8 Buscopan 0.1-0.2mkdose MAX: 0.8mkD
Prep: 250/250/5mL, 750(500+250), 0.15 mkD QID, 0.01mkdose
1.5(1g+500) Prep: 10mg/tab, 2mg/ml syr, 20mg/amp

Co-Amoxiclav Oral:20-40mkDay (based:Amox) TID Carbamazepine 10-20mkday, then 1.5-3 mkday

Adjust in RF 25-45mkDay BID 200-400MG/Tab, 100/5mL susp
IV:30-50 mkdose q8h Carbocisteine Inf: 10-20 mkday TID
Prep: 156/312 (125/250) TID Child: 30-50 mkday
228.5/457 (200/400) BID Prep: 50-100mg/mL drops; 250mg/5mL ;
375/625 (250/500) 250-500mg/cap
Captopril Premature:0.01m/kdose q8-12H
Ascorbic Acid Scurvy: 100-300mkDay Neonate:0.05-0.10mkdose q12-24H
Urinary acidification: 500mg q6hrs Children:0.30.5mkdose
Max:6m/k/24H
ASA 75 - 100 mkd Prep: 80,100,300mg/tab Cefaclor 20 - 40 mkday TID
Ad Rxn:
Kawasaki: 80-100 q6h (x2wks) during febrile Prep: 125mg/5mL, 250mg/5mL
myelosuppression,
hepatotoxicity phase or until after 3-4days afebrile then dec to Drops: 50mg/mL
3-5m/k/day OD 6-8wks after or ESR & plt Cefixime Pneumonia:10-12 mkday BID x7days
normal Typhoid: 15-20mkday BID x10-14days
Rheumatic Fever: 60-100mkday q6hr Prep: 20mg/mL drops; 100mg/5mL susp;
Contra: <16y w/ chickenpox or flu like Sx(Reye synd) 100-200mg/cap
Cefalexin 30 - 50 mkday TID
Atenolol 0.8 1.5mkday (max: 2mg/kg) Prep: 125-250mg/5mL, 250-500mg/cap
HPN, arrythmia Contra: pulmo edema, cardio shock Cefazolin 100mkday q6h IVTT
nd rd
Ad rxn: brady, hypotension, 2 /3 AV block,
wheezing, headache, constipation Cefepime 30mkdose q12 ( < 14days old))
50mkdose q8 (meningitic, severe sepsis)
Atropine sulfate Sinus brady: 0.02mkdose (min 0.1mg, MAX: 100-150mkday q8h MAX: 6 grams OD
Dose <0.1 paradoxical 0.5mg) q 5min
brady Antidote to organophosphate: 0.02-0.05mkd
Cefoperazone 100-150 mkday q8/12h
q10-20min then q1-4hr for 24hrs
MAX: 12grams OD
Prep: 1.5g/vial(1gr); 2g/vial(1gr)
Azithromycin 10-50 mkdose OD x3days
Cefuroxime 75- 100 mkday(IV) 20-40mkday (PO)
OM: 10mkD x3d MAX:500mkday
CAP(>6m): 10mkDx1 day 5mkD x4days Prep:125-250mg/5ml; 250-500mg/cap;
ATP (>2y): 12mkD x5days MAX: 500mkday 250-750/vial
Adolescents: 500mg x1day 250mg x4 days Cefpodoxime 8-10 mkday BID Po
or 500mg OD x 3days
Prep: 500mg, 2g/tab, 100/5, 200/5mL susp, Cefotaxime 50 -75 mkd0se q8h ( 150mkday )
500IV Prep: 500mg, 1 gram/ vial

Ceftriaxone 75- 100 mkday (max: 3g/day)

Prep: 250, 500, 1gr/vial

Ceftazidime 30mkdose q12(<7days old)

50mkdose q8 (>7 days old)
Prep: 250, 500, 1g, 2g/vial
Carbamazepine 10-20 mkday 1.5-3 mkday
Prep: 20mg/mL , 100mg/5mL, 200/400 tab

Cetirizine 0.25mkday OD/BID >12: 10 drops BID

Aztreonam 30mkdose q8h, inc by probenecid and furo Oral solution (1mg/ml) 6-12: 10-20 OD
monobactam Prep: 500vial Drops ( 10mg/ml) 2-6: 5 drops BID
- wt(kg) x 0.25 x20
Bambuterol 0.25-0.27mkdose OD 10
Bambec Oral sol:1mg/ml, tab 10mg Charcoal 1 2 g/kg q2-6H
 5 10 x wt of ingested poison Prep: 200/cap; 220/5ml susp
Chloramphenicol IV: 50-100mkday q6h (>75 mkday:Typhoid) Erdostein 1mkday(BID)
PO: 30-50mkday 2-6y:(10-20) 2.5ml
PreMature/NB: 25 mkday 7-12y(21-30) 5ml
Prep: 125/5ml; 250-500/cap; 1g/vial >12y (>30)

Chlorphenamine 0.35mg/kg/24H Erythromycin 30 - 50 mkday q6-8h

Maleate 2mg/5ml; 4mg/tab; 10mg/ml amp Prep: 200-400mg/5ml susp, 250-500mg/tab
Drops: 100mg/2.5ml
Cimetidine 5 mkdose Q6-8H
Ciprofloxacin 20-40 mkday Esomeprazole <10y : 10mg PO BID Prep:10mg/sachet
Typhiod relapse: 10-20mkday (nexium) 10-12y: 20mg PO BID 20-40mg/tab
Max: 500mg q12h 12-17y: 20-40mg OD
Prep: 250-500mg/tab GERD 20 mg once daily for 4 wk-8 wks
Clarithromycin 15mkday BID Dissolve 1 sachet in 15ml NC water
Clindamycin PO: 10-20mkday mild q6-8h
IV: 20-40mkday severe q6-8h Ethambutol 15 mkday
Prep: 75mg/5ml syr; 150-300m/cap; 150/ml IV
Famotidine PO= 1-1.2mkday q8-12: 20-40mg/tab
IV = 0.5mkday q8h: 25mg/2ml amp
<3mos: IV= 0.25-0.5mkday OD

Fluconazole 4-6mkday OD
Prep: 50-15-200mg/cap ; 2mg/ml vial

Clonazepam 0.01 0.03m/k/24h in 2-3 divided doses Furosemide IV= 0.5-1.0 mkdose q8h (max:4mkdose)
Prep: 2mg/tab PO=1-2mkdose q8h
Prep: 20-40mg/tab, 20mg/2ml amp
Cloxacillin 50-100 mkday q6h
Prep: 125-250mg/5ml syr; 250-500mg/cap FeSO4
4 - 6 mkday (Therapeutic) Incremin: 30mg/5ml
CoTrimoxazole 8-10 mkday BID PO 1-3 mkday (Prophylactic) Ferlin drops: 25mcg/ml
Based on Trimethoprim Preterm: 2-4mkday Ferlin syrup: 150mg/5ml
Prep: 200mg/40/5ml syr; 400/80/5ml syr Iberet: 26.25mg/5ml, 105mg/tab

Desloratadine 6-11y: 5ml OD Prep: 2.5mg/5ml Supplemental Therapeutic

(Prophylactic Dose
(aerius) 1-5 y: 2.5ml OD 5mg/tab
Age Dose)
6-11mos: 2ml OD Group

Dexamethasone 0.5-1 mkday (LD) Orally, once Orally, 3 times

0.2-0.4 mkday (MD) daily a day
Dicycloverine 1 mkdose q6h PO Prep: 10/5ml syr
(relestal/bentyl) 6-12y: 5ml 5mg/ml drops
2-5y: 2.5-5ml Oral Drops
6mos-2 yrs: 0.5-1ml 4-<6 months 0.5 mL 0.5 mL
6-12 months 0.75-1 mL 0.75-1 mL
Digoxin Neonate: 10-30mcg (LD)
1-2 years 1 mL 1 mL
Prep: 0.25mg/tab 5-10mcg (MD)
0.05mg/ml syr 1mos-2yr: 30mcg (LD)
0.25/2ml amp 10-15mcg (MD) Syrup
Child >10yo: 10mcg (LD) 2-6 years 2.5 mL ( tsp) 2.5 mL ( tsp)
2-5 mcg/k/day (MD) 7-12 years 2.5 mL ( tsp) 5 mL (1 tsp)
Doxycycline 2 - 4 mkd
100mg/cap Gentamycin 5 - 8 mkday q8h
Dimetapp 0.1 mg /k/dose(drops)
(bromphenamine + 1 - 6 mos -0.5ml TID Hemostan 10mg/kg/dose
pseudoephedrine) 2 - 24 mos 1ml TID Prep: 250-500mg/cap
syrup: 2 - 4yo 3/4 tsp TID prep: 2m/5/5ml Hydrocortisone 4-6 mkdose
4 - 12 yo 5ml TID Prep: 100-250mg/2ml; 500mg/4ml
Diazepam 0.2- 0.5 mkdose
Rectal: 0.5 (2-5y) 0.3(>6y) Hydralazine 0.15mkdose(IV) (0.1-0,2mkdose q4-6h)
Prep: 2mg, 5mg,10mg/tab, 10mg/2ml amp 0.75mkd(PO) max: 2mkdose
Prep: 25mg/tab
Epinephrine 0.01-0.03mkdose (1:10,000) (0.1-0.3ml/k) Given w/ food
Q3-5min Racecadotril 1.5mkdose(TID) Prep:10mg/sch
Erceflora (B. Clausii) >1mo= 1-2 vials/day (BID) (Hidrasec) 1 mo-9 mos: 1 sachet/dose 30mg/scht
9 mos-30 mos: 2 sachets/dose 100mg/cap
Ercefuryl <6mos: 1 tsp BID 30 mos-9 yrs: 1 sachet/dose
(nifuroxazide) >6mos: 1 tsp TID >9yrs: 2 sachets/dose
Adult: 1 cap QID Hydroxyzine PO=1-2mkday TID IV=0.5-1mkdose
 Prep: 2mg/ml syr, 10-25mg/tab
Metoprolol 1-2mkday BID
IVIg Prep: 2.5g/50cc vial Max: 6mkday
10g/200cc vial Prep: 25-50-100mg/tab
RD: 2g/kg/dose, infuse x12hrs
Test dose: 0.01-0.02 cc/kg/min Metronidazole 30 - 50 mkday (TID)
infuse for 30 mins Prep; 125mg/5ml; 500mg/tab; 500/100ml IV
Ibuprofen 5-10mkdose q6-8hr Diloxanide 20mkday TID
JRA: 30-50mkday q6h Prep: 500mg/tab; 125mg/5ml susp
Closure of PDA: <32wks=0.5-1.5kg
10mkdose x15mkdose (24 & 48hr) in 15min Mefenamic Acid 6.5 mkdose TID
Prep: 100mg/2,5ml drops; 100-200mg/5ml syr
Prep: 50mg/5ml
L- Carnitine 50-100 mkday q8-12h Max:300 Midazolam IV: 6mo-5y: 0.05-0.1mkdose max: 0.6mkd
Prep: 330mg/tab; 1gram/10ml 6-12yr: 0.025-0.05mkdose max: 10mg
>12: 0.5-2 mkdose
Lactulose Inf: 5ml/day PO: >6mos: 0.25-0.5mkdose max:20mg
1-6y: 5-10ml/day 6mo-5yr: 1mkdose
7-14y: 10ml/day
Prep: 3.3 g/5ml Motilium/ vometa 0.15-0.4mkdose q6h
Lanoxin 0.003 mkdose BID (Domperidone) 2.5ml/10kg TID
Prep: 0.25mg/tab; 0.05mg/ml elixir; not to exceed 1mkday
0.25mg/2ml amp prep: 1mg/ml syr; 10mg/tab
Lanzoprazole 15mg/FDT tab OD N- Acetylcysteine 100mg bid-qid
(prevacid) <10kg: 7.5 mg PO OD (Para antidote) Neb: inf: 1-2ml of 20% soln + equal H20/NSS
11-30k: 15mg PO QD-BID 2-4ml of 10% TID-QID
>30kg: 30 mg PO QD-BID Child: 3-5ml of 20%; 6-10ml of 10% soln
Prep: 15-30mg/FDT; 15-30mg/cap Adolescent: 5-10ml of 10% or 20%
Levocetiriine 6-12mos: 1.25mg (5drops) OD Prep: 100mg/5ml syr, 100mg/ml inh;
(xyzal) 1-6 yrs: 2.5mg/day (10drops) BID 100-200mg/sachet; 600mg/eff tab in 75cc h20
6-12yrs: 5mg (20 drops) OD or 1 tab Mometasone AR: 2-11y: 50mcg(1 spray) QD
Prep: 5mg/ml drops; 5mg/tab (nasonex) >12y: 100mcg(2 sprays) QD
Levothyroxine <6mos =25-50mcg (8-10mcd/k/dose) QD Montelukast 6mo-2y= 4mg/sachet OD in milk w/in 15 min
6-12mos = 50-75mcg (6-8) 2-5 = 4mg/tab OD
1-5 y= 75-100mcg (5-6) 6-14= 5mg/tab
6-12y = 100-150mcg (4-5) Prep:100mcg/tab >15 = 10mg/tab
>12y = 150-200mcg (2-3) 50mcg/tab Nalbuphine 0.1 - 0.2 mkdose
Loratadine 1-2y = 2.5ml Prep: 10mg/ml amp
2-12y(<30kg) = 5ml OD HS
2-12y(>30k) = 10ml Nystatin 1ml QID as oral solution 400,000 U/day
Prep: 5mg/5ml syr 1.2 M units/day
Maalox 2-4tsp/ tabs QID Nicardipine 5mg/hr by 2.5mg/hr max: 15mg/hr
(AlOH,MgOH) 1hr after meals and HS Q5-15min
Mannitol 2.5-5cc/K/dose Nifedipine 0.25 mkdose
Max: 100mg q6h Prep: 5,10,20,30,60mg/tab
Mebendazole 500 SD = 50mg/ml (10ml) Nitrofurantoin 5-7mkday q6h
100mg or 5ml BID x 3days
UTI: 1-2mkdose qHS
5ml BID x3 days 20mg/ml (30ml);
Prep: 100-500mg/tab
Ondansetron 4-11y: 4mg TID
11-18y: 8mg TID
Meclizine 12.5 - 50 mkd
Prep: 12.5 25mg/tab
Omeprazole 1mkday OD-BID (0.5-1.5)
<20kg: 10mg PO OD
Meropenem 20mkdose q8 OR 60-120mkday q8h >20kg: 20mg PO OD
40mkdose q8 meningitic
Cr cl <10 = dose q24h
Oxacillin 150-200mkday IV q6h
10-25 = dose q12h
Prep: 250-500mg/vial
26-50 = q12h
Phenobarbital MD: 5 mkday
Meperidine 0.5 mkdose
LD: 15-20 mkdose +5mkday Max: 30
Metoclopromide 1 -2mkdose q6h (IV/PO)-antiemetic 15mg/tab (gr ) 30mg/tab (gr1/2)
0.5 mkday (IV) q8 60 mg/tab(gr 1) 90 mg/tab (gr1 )
0.1-0.2mkdose QID dysmotility/ GERD
Prep: 10mg/tab; 5mg/5ml syr; 10mg/2ml IV Piperazine 75mkday x3days
Piperacillin- <6mos: 150-200MKday (piperacillin) q6-q8h of diluted formula TID
Tazobactam >6mos: 300-400mkday q6-8h Furazolidone (Furoxone) Prep: 50mg/ml, 16.7,g/5 ml
100-300mkday q4-6hrs max: 24g OD RD= 4-7 mkday
>40= 4.5g q8h Ercefuryl (40-60/ 60-100)
<40= 112.5mkdose q8h OD(60-100mkd)
Prep.: 220 mg/5 ml
Prednisone 1 - 2 mkday (preferably BID) Etofamide (kitnos) Prep. 100 mg/5ml
Prep: 5,10,20mg/tab; 10mg/5ml; 15mg/5ml sus RD= 20-40 mkday
Metronidazole Prep 125mg/5ml
Phenytoin LD: 1520m/k/day MAX: 1500mg/24hr RD= 30-50mkday
MD: 5m/k/day q12-24H Diloxanide Furamide Prep 125mg/5ml
Prep: 30-100mg/cap; 30mg/5ml; 125mg/5ml RD= 20 mkday
Secnedazole Prep:
Pen G 50,000 U q6-8h (<28 DOL) RD= 30 mkday
100,000-400,000 U/kday q6h (>28 DOL)
ANTISPASMODICS
Procaterol <5y= 0.25ml/kg BID/ TID Dicycloverine - 0.15mkday
>6y= 5ml OD HS/BID Bentyl 10 mg/tab, 20mg/ml
Prep: 100mcg/ml inh; 5mcg/ml syr; Relestal 10mg/5ml, 5 mg/ml
25-50mcg/tab Hyoscine Butyl Bromide 10mg/tab, 5 mg/ml
(Buscopan)
Ranitidine 1 - 2 mkdose Diphenhydramine (BENDARYL) Syrup: 12.5 mg/5ml
Prep: 75mg-15-300mg/tab; 20mg/2ml amp Cap - 25 mg
Inj - 50 mg/ml
Simethicone <2y= 0.5ml TID-QID 3-5 mkday po
(Restime) >2y= 1ml TID 1 mkdose IV
Prep: 40mg/ml ANTIFUNGAL
Mycostatin Tab: 1-2 tabs TID
Sucralfate 40-80mkday q6h Susp: infant 2ml QID
Prep: 1g/tab Children- 4-6 ml QID
Oral Susp : 2 ml QID
Theophylline 20 mkd to be swabbed on lips and
buccal mucosa
Terbutalline 0.075 mkdose Difflucan (Fluconazole) 4-6 mkday
Tetracycline 25-50mkday q6h 50 mg/tab 1 tab divided into
4pptabs 1pptab OD with milk
Timentin 80mg/k Q6-8H PO/IV=3-6mkday OD/q12H
80mkdose q12H (termNB) Bronchodilators
Tobramycin <7days 5 mkdq12 Aminophylline RD= 3-5 mkdose
<5y 7.5 mkdq8 dilute with equal amt of IVF
5 -10y 6 mkd q8 refer for vomiting,
Valproic Acid 15 mkday hypotension, H/A, Sz,
tachycardia
Vancomycin 10 q 12 mkdose q8h (severe:15mkdose q8)
40-60mkday q6h Theophylline syrup 80mg/15ml
(Nuellin) Tab= 50 mg, 125 mg
Zafirlukast 40mg/day PO q12H (20mg/tab)
RD= 4 mkdose
(Accolate)
Budesonide
Zertin/Erdostein 7.5 mkdose q12 Adrenal corticosteroid
Anti-inflammatory
Zinc syrup

Antikochs Treatment Emergency Drugs

NaHCO3 1-2 meq/kg/dose
Kidz Kit3 INH 200mg/5ml Atropine 0.04 mk SQ
RIF 200mg/5ml 0.02 mkdose IV
PZA 500mg/5ml Epinephrine 0.01 mkdose (1:1000)
Kidz Kit3 Forte INH 200mg/5ml 0.1 mkdose (1:10000)
RIF 200mg/5ml max. 3 ml q5-10 mins
PZA 500mg/5ml
Ethambutol DRIP:
Myrin P 0.6 x wt(kg) x ug/k/min = __mg in 100mL of
Streptomycin mL/Hr D5W/NS

= 1mL/Hr will deliver 0.1 ug/k/min

Naloxone 0.1 mkdose
Mannitol 0.5-2 gkdose
1g= 5cc
Albumin 0.5-1 g/K
Prep: 25g/100cc
AGE Drugs 12.5/50cc
Infloran Berna dissolve contents of 1 cap in 15 ml Dilute in 50cc D5W x20-25 ugtts/min
Dobutamine Prep: 250mg/20cc Prep: 10 mg/mL ampule
12.5 mg/cc Dose:
cc/Hr = wt x ugm x 60 Infant/Child: 0.05m/k/hr (titrate to clinical effect)
500 Adult: 0.1 m/k/hr (max: 0.4 m/k/hr
= 2 CC+ 48 cc D5W
Wt(kg) x DD x 24h = __mg in 24 mL of NS to make 1
DRIP: cc/hr = 0.1 mg/kg/hr
2.5 15 ug/kg/min (max: 40ug/kg/min) OR
Peak effect: 10-20 min Wt(kg) x DD x 24 x 5 = __mg in 120mL of NS to make 5
Preparation: mL/hr = 0.1mg/kg/hr
12.5mg/mL x 20mL/_ = 250mg/mL IV infusions = 6 x Desired dose(ug/k/min) x wt(kg) = mg drug
Premix: Desired rate(mL/Hr) 100mL fld
1000ug/mL x 250mL = 250mg/250mL
2000ug/mL in 250mL = 500ug/250mL
Medication Usual Dilution in IV Infusion Rate
= 6 x wt(kg) = __mg in 100mL Dose 100mL D5W
* 250mg in D5W 250cc (1mg/mL) Dopamine 2-20 6mg/kg 1 mL/Hr=1ug/kg/min
Ugtts/min = wt(kg) x DD Dobutamine 2.5-15 6mg/kg 1mL/Hr=1ug/kg/min
16.6 Epinephrine 0.1-1 0.6mg/kg 1mL/Hr=0.1ug/kg/min
= wt(kg) x DD x 0.06
Lidocaine 20-50 0.6mg/kg 1mL/Hr=1ug/kg/min
* 500mg in D5W 250cc (2mg/mL)
Prostaglandin E 0.05- 0.3mg/kg 1mL/Hr=0.05ug/kg/min
Ugtts/min = wt(kg) x DD
0.1 For Patency of PDA:
33.2
-IV: begin infusion at 0.05-
= wt(kg) x DD x 0.03
0.1ug/kg/min, when
desired effect is achieved,
dec to 0.05-0.025-
PH<7.35 PH7.35- PH7.40- PH>7.45
0.01ug/kg/min
7.45 7.45
-if unresponsive, inc to
PCO2 <35 Part comp Comp met Comp Resp alk 0.4ug/kg/min
met acid acid resp alk -Ampule: 500ug/mL
Eg. 2.6kg
2.6kg x 0.05ug/kg/min x60
PCO2 Met acid Normal Normal Met alka
500ug/mL
35-45 =0.02
PCO2 >45 Resp acid Comp Comp met Part comp Terbutaline 0.1- 0.6mg/kg 1mL/Hr=0.1ug/kg/min
resp acid alka met alka 0.4

Dopamine Prep: 40, 80, 160 mg/ml

Cc/hr = wt x ugm x60
Daily Fluid Requirement
(200/250) 400 or 800 (400/250)
(1:100) (1:50) Weight (kg) D0-2 D3-4 D14-30
DRIP: 750g 1kg 110 140 150
Premix: 200mg/250mL; 400mg/250mL 1 - 1.25 100 130 140
Prep: 40mg/mL x 5mL/amp = 200mg/mL 1.25 1.5 90 120 130
>1.5 80 110 130
= 6 x wt(kg) = __mg in 100mL Add 25% if with PHOTO
(1mL/Hr = 1 ug/kg/min)
*200mg in D5W 250cc
Ugtts/mins = wt(kg) x desired dose(DD)
13.3
= wt(kg) x DD x 0.075
*400mg in D5W 250cc
Ugtts/mins = wt(kg) x DD
26.6
= wt(kg) x DD x 0.0375
Dopamine/Dobutamine
Wt x desired x 60 x24
Concentration
Ca 100-300 mkday (oral)
Gluconate 1cc/kg (LD-IV)
1 cc/kg/day (MD-IV)
Epinephrine (mg)/100cc x X/1cc x 100
Drip
cc/Hr= wt. X 0.3 -1 x 60
40
Prep: 1 amp in 25cc D5W Ph PCO2 HCO3 BE
Acetazola- 250mg/tab Met Acid
mide 30 mkday q8H
Uncompensatd N (-)
NaHCO3 325mg/tab
8-10 mkday q8H Partly comp (-)
Furosemide Drip:
Complt comp N (-)
Met Alka
Uncompnsatd N (+)
BUN Mg/dL (x0.357) mmol/L
Partly Comp (+) Cordbld 21-40 ***** 7.5 - 14.3
Complt Comp N (+) Prem 3 - 25 ***** 1.1 - 9
NB 3 -12 ***** 1.1 - 4.3
Resp Acid Inf/Child 5 -18 ***** 1.8 - 6.4
Uncompnstd N N Thereafter 7-18 ***** 2.5 - 6.4
Partly Comp PPN
Vamin : 100 x wt x dose
Complt Comp N Preparation(%)
Resp Alka
Uncomp N N Ca Gluc: 2cc/kg/day
BNC: 0.5-1cc/day
Partly comp IVF: accdg to TFI
Complt Comp N
Cholesterol
Caloric Equivalent: Total mg/dl = mmol/L
1-3yr : 45-182 = 1.15 - 4.70
D50 2 4-6yr 109-189 = 2.80 - 4.80
D10 0.4 6-9yr 5-75-95 5 -75- 95
D5 0.2 M 126-172-191 = 3.26- 4.45-4.94
D7.5 0.3 F 122- 173- 204= 3.16- 4.47-5.41
D12.5 0.6 10-14yr
M 130-179-204 = 3.36-4.63-5.28
Amino acid 0.2
F 124-174-217 = 3.21-4.50- 5.61
Intralipid 1.1
15-19yr
Vamin 0.67 M 114-167-198 = 2.95-4.32-5.12
Corn oil 8.4 F 125-175-212 = 3.23-4.53-5.45
Karo, Aminosteril 4
MCT 7.6 Albumin
Olive Oil 9 Prem 1 day - 1.8 -3.0 g/dl -- 18-30g/L
Breastmilk 20 /oz Fullterm <6days 2.5 - 3.4g/dl -- 25-34g/L
<5 yr 3.9 - 5.0g/dl -- 39 - 50g/L
PreNan 24
5-19yr 4.0 - 5.3g/dl --- 40 - 53g/L
NAN 22
Enfalac 24 Protein
Pediasure 225kcal/225mL Prem 4.3 -- 7.6g/dl --- 43-76g/L
Newborn: 4.6 -- 7.4 g/dl --- 46 - 74g/L
Na 1--7 yr 6.1 -- 7.9 g/dl -- 46-74g/L
NB - 134- 146 8-12yr 6.4 -- 8.1 g/dl -- 64 - 81g/L
Infant - 139- 146 13 -19yr 6.6 -- 8.2 -- 66 - 82 g/L
Child - 138 - 145
Thereafter - 136 - 146 Corrected Reticulocyte: observed retic x observed hct
Normal hct for age
K
<2mos 3.0 - 7.0 Dextrosity:
2- 12 m 3.5 - 6.0 D5 = 50 glucose D10 = 100 glucose D12.5 = 125 glucose
>12m 3.5 - 5.0 Limits of Dextrosity: Peripheral Line: D12
Central Line: D20
Ca
Cordblood - 2.25 - 2.88 Total Fluid Intake (TFI): Term: 60-80; Preterm: 80-100
NB - 2.3 - 2.65 TFI: Rate (cc) x 24 hr
24-48H - 1.75 - 3.0 Wt(kg)
4-7d - 2.25 - 2.73 Computation:
Child - 2.2 - 2.7 Wt(kg) x TFI = ___ divide 3 (soluset: 100cc)
Thereaftr - 2.1 - 2.55
To adjust dextrosity 10: eg. TFI: 90
D5IMB 80 x 0.05 = 4
D50W 10 x 0.50 = 5
90 9
Crea Mg/dl (x88.4) umol/L Check: 9 / 90 x 100 = 10 = Dextrosity: 10
Cordbld 0.6 -1.2 === 53 -106 Then, 90 x 3 (q8h cycle) = 11.25cc/hr
NB 0.3 -1.0 === 27-88 24h
Infant 0.2 - 0.4 === 18 -35 chart: 90cc x 11cc/hr q8h
Child 0.3 - 0.7 === 27 -62
Adolescent 0.5-1.0 === 44 -88
Adult M: 0.6-1.2 == 53-106
F: 0.5 - 1.1== 44-97
 IVF Na Cl K Ca Lactateac
Composition etate CPAP
0.9NSS 154 154 Requirement : adequate spon. Respiration
0.3NaCl 51 51 Components : O2 pressure
LR 130 109 4 1.5 28lact Indications:
NR 140 98 5 1.5 27acet 0. HMD
23gluc 1. Inhalation/chemical pneumonitis
NM 40 40 13 1.5 16lact 2. Severe pneumonia
3. Meconium aspiration
Imb 25 22 20 1.5 23acet
4. Pulmo edema with or without assoc. CHF
5. Fluid overload
Then, compute for: 6. General atelectasis
GIR: Rate(cc) x dextrosity x0.167 7. Infants with apnea of prematurity
Wt 8. Infants with ARDS
OR 9. PaO2 < 50-60 mmHg, breathing
Dextrosity x IVF rate x10 60-70 with recurrent apnea
Wt(kg) x 60
WEANING
1. Improvement in CXR
Normal Values: 2. ABG with PO2 > 50 mmHg
NB/Infants: 6-8 mg/kg/min 3. Blood pH > 7.3
Children: 4-6 mg/kg/min 4. PCO2 < 55 mmHg
If hypoglycemic, may increase GIR to 15 mg/kg/min 5. Hg 12-15 gm/Hct 36-45

GUIDELINES
Blood glucose monitoring: 1. DEC. FiO2 by 3-5% every time PO2 . 70
- Monitor CBG q6-8h 2. With FiO2 = 40%, dec. Pressure by increments of 2 cm H2O if 2-4H until 2-
- if CBG40mg/dL, give d10W 2cc/k/dose as slow IV push, get 3 cm is reached
CBG q15 mins, then q1Hr until stable 3. Transfer patient to O2 hood with FiO2 of 15-50%
- if feeding, no need to monitor
- if CBG is persistently LOW, check IV line Extubation
- may need to increase dextrosity 1. Dexa 0.5mkd IVTT Q12H x2 doses prior to extubation
2. Salbuamol 0.5cc + NSS 0.5cc Q8H
Peak Flow: 3. Epinephrine 0.2mkd Q4H x 2 doses
Ht in cm - 100 x5 +175(M) 4. Dexamethasone Q12H x 2doses after extubation
170(F) 5. Chest physiothearpy
6. Keep on right side position
Albumin: wt (g/Kg) x quantity of Stock(50cc or 100cc) 7. NPO x 2h
% PAI with 4.7cc NSS + 0.3cc Epinephrine QH x3 doses then maintain on
PAI with 2cc NSS Q6H.
IVF: cc/h x 24h x Dextrosity x 3.4 VENTILATOR PLANS
100 HMD PEEP = 4-6 cm H20 PFC PEEP= 2 cm H20
PIP = 18-30 cm H20
Aminosteril: wt x g/k x 100
% Oxygenation Status
Cal: cc/day x % X 4 At room air, sea level:
100 PaO2 80 -100 Normal or acceptable
<80 mild hypoxemia
Materials for Surfactant instillation:
<60 moderate hypoxemia
- Gloves #3 - OGT F8
<40 severe hypoxemia
- Syringe 10cc (2) - Ruler
On oxygen support:
- Betadine - Cotton balls
PaO2 80 - 100 corrected hypoxemia
- ET size (same brand as inserted) - Ambubag
>N overcorrected hypoxemia
<N uncorrected hypoxemia
Post Surfactant
- Maintain on NPO ROMS - resp opposite; metabolic same
- CXR-APL Metabolic Acidosis:
- VBG/ABG 1 hr after 1. RTA
- B1B2, BUN, Crea, with S. Na, K, Ca 2. DKA; Starvation
- Wean FiO2 by 5% every 1-2 hrs pulse ox guided for O2 Sat >95% until 40 - 3. Lactic acidosis
50%
- No suctioning at least 1 hour aftre instillation unless with bradycardia, Metabolic Alkalosis:
cyanosis, hypotension, or obstruction 1. Hypokalemia
- Watch out for pneumothorax 2. Hypochloremia
- Standby butterfly G23, 10cc syringe, 3-way stopcock, betadine, cotton 3. Vomiting
applicator, gloves 4. Massive steroid administration
5. NaHCO3 administration
PNUEMONIA IN CHILDREN
0-3 mos C. trachomatis, S. aureus, Gr neg
4-11 mos S. Penumonia, H. influenzae
12-59 mos S. Pneumonia, H. influenza
>60 mos M. Pneumonia, S. pneumonia
Respiratory Acidosis: Weigh Patient daily pre-breakfast/post-voiding
1. Hypoventilation
a. inadequate resp effort TFR: BSA x Insensible water loss + UO
CNS problem UO- if with Furosemide divide by 2
Neuromuscular disease
Mechanical ventilator setting TUNE/MENDOZA PROTOCOL
b. upper airway not patent WK Methylpred Dose PRED
c. decreased lung tissue 1-2 30mg/kg 6 none
d. decreased lung compliance 2x/wk
2. Abnormal ventilation perfusion ratio 3-10 30mg/kg 8 2mg/kg/48h
a. obstruction of small airway wkly
b. atelectasis 11-18 30mg/kg 4 W/ or w/o
c. pneumonia q2wks tapering
d. pulmonary edema 19-50 30mg/kg 8 Slow
3. Increased extrapulmonary shunt q4wks tapering
a. pulmonary vasoconstriction 51-82 30mg/kg 4 Slow
* RDS, severe infection q8wks tapering
b. Pulmonary hypoplasia
c. Cyanotic heart disease
Elises Protocol:
12 months - Monthly--- 3 consecutive days
Respiratory Alkalosis 6 months - 1 dose/ monthly --- cont prednisone 2 mg/kg
1. with hypoxamia
q other tapering
a. acute pulmonary disease -
- pneumonia and atelectasis, RDS, acute asthma Alkylating Agents
b. Acute myocardial disease
Cyclophosphamide - 2.5mg/kg/day X 8wks
- MI, pulmonary edema, heart failure, CP bypass
- (Nelson) 3mg/kg/24h x 12wks
2. Without hypoxemia
- (Total 140mg/kg)
a. anxiety, neurosis, psychosis 2
- 500mg/m (BSA) 750mg 1g
b. pain
Cyclosporine - 5mg/kg/day
c. CNS disease
- immunosuppressive, altered perselectivity
d. Anemia
- steroid- sparing drug
e. Carbon monoxide poisoning
- high relapse rate when D/C
NEPHROTIC SYNDROME
st
TREATMENT: 1 Episode Chlorambucin - 0.2mg/kg/day x 8-12 wks
2
4weeks: 60mg/m /day divided doses (max 80md/day) - hematologic malignancy
2
4weeks: 40mg/ m / alt days single am dose (max 60mg)
2
8days: 20mg/ m / alt days single am dose (max 20mg) Nitrogen Mustard - 1958
2
8 days: 10 mg/ m / alt days single am dose (max 10mg) LTVamisole - 2.5mg/kg/alternate days
- maintain in remission in about 50% of losses of
MCNS: relapse treatment (Eddy) steroid - dependent NS
2
Until urine remission: 60mg/ m /day in divided doses RENAL BIOPSY
2
8 days: 60mg/ m alt days single am dose
2
8 days: 40mg/ m alt days single am dose LUPUS NEPHRITIS IN CHILDHOOD
2
8 days: 30mg/ m alt days single am dose Classification
2
8 days: 20mg/ m alt days single am dose I - normal
2
8 days: 10mg/ m alt days single am dose II - pure Mesangiopathy (mesangial 19-27%
Remission - absence of proteinuria 5 consecutive days III - Segmental & Proliferaive GN (Focal Segmental
Difficult patients: - 18 - 24%)
1. Steroid resistent IV - Diffuse Proliferative Lupus Nephritis (39-44%)
2. Steroid dependent - 2 relapses/ 14 days after V - Diffuse Membranous GN - (8-22%)
discontinuation od decrease in dose VI - Advanced Sclerosing GN
3. Steroid toxic
4. Steroid Dependent/ Frequent relapsers - 2 relapses in 6 mos. Seroassay-
1. ANA - unusual in children
Dr. James Woo - ANA titer does not correlate with disease severity
BSA: wt X 4 +9 TFR: BSAx 500(<20k)/400 (>20k) + U.O
100 2. Antibodies to ds DNA & Smith (Sm) Antigen more specific level may
present in 70% of 25%
Dr Alcala/Caso BSA- Wt in Kg x Ht in CM
3600 Anti ds DNA + Anti-Sm Ab + Serum C3 -

Post Streptococcal Acute Glomerulonephritis Renal Disease Activity

Diet: Low Salt diet C3
Labs: CBC,plt Na, K
BUN, Crea C3 C3a, C5a C5b-a
ASOT
IVF: D5.03 NaCl (no KCl first)
Furosemide (1-2mkdose, max:4mkdose);Hold:BP<80sys Leukocytes membrane attack
Pen G/ Ampicillin-Sulbactam
Limit Oral intake to TFR Hyperkalemia
Watch out for HPN Serum K >5.5meq
1. Sodium Bicarbonate - shifts K into cells ECG
- 1 meq/kg IV over 10 - 30 min
- onset 15-30 min
2. Calcium Carbonate - (10%) - stabilizes membrane potential AVR AVL
- 0.5 -1ml/kg over 5-15 min
- onset immediate (+)I
3. Glucose and Insulin - stimulates cellular uptake of K
- glucose 0.5 mg/kg witn insulin 0.1mg/kg over 30
min (+)150 (+30)
- onset: 30 - 120 min (+120) (+)60
4. B - Agonist (Albuterol/Salbutamol) - stimulates cellular III (+90) II
uptake of K AVF

HYPOKALEMIA - 0.5-1 meq/kg/dose X 1h QT -

- continuous correction: 0.2-0.3 meq/kg/hr PR
- fast correction K (symptomatic) QT
0.5meq/kg/hr (child) x10 meq KCl in 166 ml fluid x 1-2hr[s Rate
max 40meq KCL/500cc PNSS x 1-2 hrs Axis
- ICU - 10meq/10cc (1:1) central line
- Oral: 10% oral KCl soln has 1.34meq/ml AGE Preterm Newborn Infant 1 year
Wt (kg) 1.5 3 5 10
FT Consider Photo # * ETT size 2.5-3.0, 3.0-3.5, 3.5-4.0, 4.0-4.5,
Photo uncuff uncuff uncuff uncuff
24H Suction 5 6 8 8
25-48H 12 15 20 25 catheter
Chest tube 8-10 10-12 10-12 16-20
NGT/Foley 5 5-8 5-8 8
49-72H 15 18 25 30
Laryngoscope 0 1 1 1-2
Mask NB NB NB- Infant
>72H 17 20 25 30 infant
# DVET if photo fails
* DVET and intensive photo AGE 3 yr 6 yr 10 yr Adolescent
Photo for 1500g 1500-2000 >2000 Wt (kg) 15 20 30 50
Preterms ETT size 4.5-5.0, 5.0-5.5, 6.0-6.5, >6.5, cuffed
uncuff uncuff cuffed
<24H >4 >4 >5
Suction 8-10 10 10 10
24-48H >5 >7 >8 catheter
49-72H >7 >9 >12 Chest tube 16-20 20-28 28-32 32-40
NGT/Foley 8-10 10-12 12-14 14-18
72H >8 >10 >14
Laryngoscope 2 2 2-3 3
Mask Child Child Adult Adult
DVET for 1500g 1500- >2000g
Preterms 2000g
<24H >10-15 >15 >16-18
24-48H >10-15 >15 >16-18 Technical Updates of the Guidelines on Integrated
49-72H >10-15 >16 >17-19 Management of Childhood Illnesses (IMCI)
>72H >15 >17 >18-20 Acute Respiratory Oral amoxicillin should be used in
Infections 25mg/kg/dose twice daily for the
Polin treatment of non-severe pneumonia
Wt (PT) Photo DVET Oral amoxicillin should be given for three
<1.25 5-7 10-13 days for non-severe pneumonia in
1.25-1.49 7-10 13-16 children 2-59 months of age
1.5-1.99 10-12 16-18 Where referral is difficult and injection is
2.0-2.5 12-14 18-20 not available, oral amoxicillin in
45mg/kg/dose twice daily should be
Sick Infant
given to children with severe pneumonia
Age Photo Exchange
<24H 10-14 20
for 5 days
>24h 15 20 Injectable Ampicillin plus injectable
gentamicin is a better choice than
Healthy injectable chloramphenicol for very
Age Photo ET if Photo fails DVET severe pneumonia in children 2-59
25-48 >15 >20 >25
months of age. A pre-referral dose of
7.5mg/kg intramuscular injection
49-72 >18 >25 >30
gentamicin and 50 mg/kg injection
>72 >20 >25 >30
Ampicillin can be used
Children with wheeze and fast breathing
and/or lower chest indrawing should be
 given a trial of rapid-acting inhaled
bronchodilator (up to 3 cycles) before
they are classified as pneumonia &
prescribed antibiotics. 0.5ml Salbutamol
diluted in 2 mL of sterile water per dose
nebulization should be used.
Diarrheal Disease Ciprofloxacin is the most appropriate drug
in place of nalidixic acid which leads to
rapid development of resistance

RTD: Clinical Practice Guidelines in Pediatric Pulmonary Tuberculosis

- Dr. A. Jiao
Latent TB
- infection with MTB, (+)Mantoux test, no clinical s/sx or CXR of TB
- implies devt of antibody of TB, exposure to TB
- carries high risk of progressing to TB disease
- carries high risk of progressing to TB disease

Bedside NEPHROLOGY
Urinalysis
- examined within 30 min
- can be preserved for up to 6 hours in 4C
Interpretation of Urinalysis:
COLOR:
Yellow Normal Dark red Hemoglobin/Myoglobin
Tea-colored Blood Black Hemolysis
Greenish Bile Milky Fat/Chyle
Brown Nitrofurantoin Red Rifampicin
CLARITY:
Clear Normal Cloudy Infection, casts, protein
pH: N= 4.5-6.5
Acidic Alkalotic
Resp/ Metab acidosis Resp/ Metab acidosis
UTI by E. coli UTI w/ urea-splitting org
HypoKalemia Renal tubular acidosis
Starvation Vegetarian diet
High protein diet Prolonged urine storage
PROTEIN:
T race = <0.2 g/L protein 1+ = 0.3
2+ = 1 3+ = 3 4+ = >20