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Material Safety Data Sheet
Poloxamer 182 MSDS
Section 1: Chemical Product and Company Identification
Product Name: Poloxamer 182 Contact Information:
Catalog Codes: SLP1678 Sciencelab.com, Inc.
14025 Smith Rd.
CAS#: 9003-11-6 Houston, Texas 77396
RTECS: MD0907950 US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA: TSCA 8(b) inventory: Poloxamer 182
Order Online: ScienceLab.com
CI#: Not available.
CHEMTREC (24HR Emergency Telephone), call:
Synonym: Pluronic L62; Pluronic 182; Block Copolyer of 1-800-424-9300
Ethylene Oxide and Propylene Oxide
International CHEMTREC, call: 1-703-527-3887
Chemical Name: Oxirane, methyl-, polymer with oxirane
For non-emergency assistance, call: 1-281-441-4400
Chemical Formula: (C3-H6-O.C2-H4-O)x or HO(C2-H4-
O)a(C3-H6-O)b(C2-H4-O)aH
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Poloxamer 182 9003-11-6 100
Toxicological Data on Ingredients: Not applicable.
Section 3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of
inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4: First Aid Measures
Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention if irritation occurs.
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Skin Contact:
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water
may be used.
Serious Skin Contact: Not available.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Serious Inhalation: Not available.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: OPEN CUP: 466C (870.8F) (Cleveland.).
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of open flames and sparks,
of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill:
Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill:
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Precautions:
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a
fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. If ingested, seek
medical advice immediately and show the container or the label.
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Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.
Section 8: Exposure Controls/Personal Protection
Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective
threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection: Safety glasses. Lab coat.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
handling this product.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid. (Clear to slightly hazy liquid.)
Odor: Polyol (Slight.)
Taste: Not available.
Molecular Weight: 2500 g/mole
Color: Not available.
pH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: -4C (24.8F)
Critical Temperature: Not available.
Specific Gravity:
Specific Gravity: 1.03 (Water = 1) @ 25 C Bulk Density: 8.6 lb/gal @ 25 C
Vapor Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
Solubility:
Partially soluble in cold water. Solubility in water @ 25 deg. C: 10%
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat
Incompatibility with various substances: Not available.
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Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Eye contact.
Toxicity to Animals: Acute oral toxicity (LD50): 3000 mg/kg [Mouse].
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:
May contain trace amounts of Ethylene Oxide, Propylene Oxide, and 1,4-dioxane, chemicals known to th estate of California to
cause cancer and/or birt defects or reproductive harm.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: May cause mild to moderate temporary eye irritation.
Inhalation: No information Ingestion: May cause gastrointestinal tract irritation with hypermotility, and diarrhea. Chronic
Potential Health Effects: Skin: Repeated or prolonged skin contact may reslult in slight, temporary irritation. The toxicological
properties of this substance have not been fully investigated.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
Section 15: Other Regulatory Information
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Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,
birth defects or other reproductive harm, which would require a warning under the statute: ethylene oxide, propylene oxide,
1,4-dioxane California prop. 65: This product contains the following ingredients for which the State of California has found to
cause reproductive harm (female) which would require a warning under the statute: ethylene oxide California prop. 65: This
product contains the following ingredients for which the State of California has found to cause cancer which would require a
warning under the statute: ethylene oxide, propylene oxide, 1,4-dioxane TSCA 8(b) inventory: Poloxamer 182
Other Regulations: Not available.
Other Classifications:
WHMIS (Canada): Not controlled under WHMIS (Canada).
DSCL (EEC):
This product is not classified according to the EU regulations. Not applicable.
HMIS (U.S.A.):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection: a
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 1
Reactivity: 0
Specific hazard:
Protective Equipment:
Not applicable. Lab coat. Not applicable. Safety glasses.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 11:31 AM
Last Updated: 05/21/2013 12:00 PM
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lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.com
has been advised of the possibility of such damages.
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