FACULTY OF PHARMACY

KARPAGAM ACADEMY OF HIGHER EDUCATION

(DEEMED TO BE UNIVERSITY UNDER SECTION 3 OF UGC ACT 1956)
Coimbatore 641 021.

SYLLABUS
FOR
B. PHARMACY DEGREE COURSE
2015-2016
1
 SYLLABUS FOR
B. PHARMACY DEGREE COURSE (2015 2016)

SEMESTER I

[Link] TITLE OF THE COURSE L T P C CIA ESE TOTAL

THEORY
15PYU101 Human Anatomy, Physiology & Health 3 0 0 3 40 60 100
Education -I
15PYU102 Pharmaceutical Inorganic Chemistry-I 3 0 0 3 40 60 100
15PYU103 Pharmaceutical Organic Chemistry-I 3 0 0 3 40 60 100
15PYU104 Pharmacognosy and Phytochemistry-I 3 0 0 3 40 60 100
15PYU105 Biostatistics & Computer Applications-I 3 0 0 3 40 60 100
PRACTICAL
15PYU111 Human Anatomy, Physiology & Health 0 0 3 2 40 60 100
Education -I
15PYU112 Pharmaceutical Inorganic Chemistry-I 0 0 3 2 40 60 100
15PYU113 Pharmaceutical Organic Chemistry-I 0 0 3 2 40 60 100
15PYU114 Pharmacognosy & Phytochemistry-I 0 0 3 2 40 60 100
15PYU115 Biostatistics & Computer Applications-I 0 0 3 2 40 60 100
TOTAL 15 0 15 25 400 600 1000
TOTAL CONTACT HOURS/WEEK 30

2
15PYUG101 HUMAN ANATOMY, PHYSIOLOGY AND 3003100
HEALTH EDUCATION I (THEORY)
OBJECTIVES:
This subject is designed to impart fundamental knowledge on the structure and
functions of the various systems of the human body.
It also helps in understanding both homeostatic mechanisms and homeostatic
imbalances of various systems of the body.
Since a medicament, which is produced by the pharmacist, is used in various disease
conditions to correct the abnormal functioning of the body systems, the basic
knowledge of this subject is must for a student to understand how drugs act on various
systems/organs in correcting the disease state of organs/systems.
Thus it becomes a prerequisite subject for the pharmacy course.

INTENDED OUTCOMES:

Students undergoing this able to

Understand the gross morphology, structure and functions of various organs of the
human body.
Understand the various homeostatic mechanisms and their imbalances
Identify the various tissues and organs of different systems of the human body.
Perform the hematological tests like blood cell counts, hemoglobin estimation,
bleeding/clotting time, etc and also record blood pressure, ECG, heart rate, pulse and
respiratory volume.
Appreciate coordinated working pattern of different organs of each system
Appreciate the interlinked mechanisms in the maintenance of normal functioning
(homeostasis) of the human body.

3
Unit - I
Introduction to anatomy and physiology and health education with basic terminology-
Introduction to Cell physiology- Different type of cells- cell membrane physiology and
development of Action potential- impulse transmission- cardiac and skeletal muscles
Electrophysiology- Cell stimulation and neuronal functions- Tissues types and characteristics
- epithelial- connective- muscular and nervous tissues- Structure and function of joints and
bones - skeleton- types of joints and their disorders.

Unit - II
Composition and functions of blood including their disorders- Blood grouping and its
significance- the mechanism of coagulation-bleeding and clotting disorders- Formation of
lymph and its composition- Reticular endothelial system and its functions.

Unit - III
Anatomy and physiology of cardiovascular system - heart- blood circulation - systemic-
hepatic- Pulmonary- fetal and circle of Willis- cardiac cycle- heart rate-blood pressure and
its regulation- ECG and heart sounds.

Unit - IV
Gross anatomy of the G.I.T and its physiology with special reference to liver- pancreas and
stomach- Digestion- absorption- movements of intestine and disorders of digestive system-
constipation- diarrhea and vomiting.

Unit - V
Anatomy of respiratory tract- mechanism of respiration lung volumes- transport of oxygen
and carbon dioxide. Disorders like cyanosis- mountain sickness and Caissons disease.
Cough and sneezing reflex. Structure and functions of kidney and urinary tract. Physiology
of urine formation and acid-base balance.

4
TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Ross and Wilson Churchill
1 Anne Waugh and Anatomy and Physiology Livingstone 2013
Allison Grant in Health and illness Elsevier-UK

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Human Physiology-Vol. Medical Allied
1 [Link] I & II Agency-Calcutta 1997

2 Gerard J Tortora- Principles of Anatomy Wiley-USA 2014

Bryan Derrickson and Physiology
3 Cinnamon Van Seeleys Fundamentals of TataMc
Putte Human Anatomy and Graw Hill-New 2009
Physiology Delhi

WEBSITES:
[Link]
[Link]
[Link]

5
15PYUG111 HUMAN ANATOMY, PHYSIOLOGY AND HEALTH 0032100
EDUCATION I (PRACTICAL)

1. Guidelines in laboratory discipline

2. Introduction to microscope
3. The study of common objects
4. Hemocytometry
5. Estimation of Bleeding time
6. Estimation of Clotting Time
7. Determination of RBC
8. Determination of WBC
9. Estimation of hemoglobin content
10. Determination of ESR

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Godkar P.B and Textbook of Medical Bhalani Publishing
1 Godkar D.P Laboratory Technology House, Mumbai 2007

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Tata McGraw Hill
1 Mukherjee, K.L Medical Laboratory Publishing Company 2010
Technology Ltd. New Delhi

6
15PYUG102 PHARMACEUTICAL INORGANIC CHEMISTRY I 3003100
(THEORY)
OBJECTIVES:
The organic chemistry section deals with classification and nomenclature of organic
compounds, structural isomerism, and intermediates formed in reactions, important
physical properties, reactions and methods of preparation of compounds.
The syllabus also emphasizes on mechanisms and orientation of reactions.
The analytical chemistry section designed to enable the students to have fundamental
knowledge of volumetric analysis and determination of impurities in Pharmaceuticals.

INTENDED OUTCOMES: Students undergoing this able to

Write the structure, name, type of isomerism of the organic compound

Write the reaction, name the reaction and understand the orientation of reactions
Account for reactivity/stability of compounds,
Identify/confirm the organic compound
Know the principle of volumetric analysis of drugs.

Unit I
Learning symbols and valency of elements. Writing molecular formula- balancing the
equation Pharmacopoeia and monograph. Development of periodic table of the modern
concept of atomic structure and its importance.

Unit II
Importance of quality control- sources and types of impurities in pharmaceutical substances.
Test for purity Swelling power in bentonite- acid is replacing capacity of antacid-
presence of iodates and ferric ion. Limit test Definition- importance- general procedure for
limit test for chloride-sulphate- iron- arsenic- heavy metals and lead. Modified limit test for
chloride and sulphate in potassium permanganate- sodium bicarbonate and sodium
salicylate. Modified limit test for chlorinated compounds in sodium benzoate.

7
Unit III
Nuclear reactions- radioactivity- nomenclature- units- detection and measurement of
radioactivity- clinical applications and dosage- hazards- precautions and storage- biological
effects of radiation. Radio pharmaceutical preparations and standards of radioactive material

such as131Iodine-58Cobalt. Radio opaque contrast medium-barium sulfates.

Method of preparation- assay- identification test-test for purity- storage conditions- official
preparations and uses of inorganic compounds in the following categories:

Unit IV
Gastrointestinal agents and related compounds: Acidifiers - Dilute hydrochloric acid-
Sodiumphosphate- Ammoniumchloride. Antacids - Classification- qualities of ideal antacid-
side effects- advantages- combination therapy-acid neutralizing capacity-sodium bicarbonate-
potassium citrate- aluminium hydroxide gel- dried aluminium hydroxide gel-aluminium
phosphate- magnesium hydroxide-light and heavy magnesium trisilicate-light and heavy
magnesium carbonate- calcium carbonate- magaldrate and bismuth carbonate. Adsorbents
and protectives - Light kaolin- heavy kaolin and bismuth sub-carbonate. Saline cathartics -
Magnesium hydroxide-magnesium sulphate- magnesium carbonate and Sodium phosphate

Unit V
TopicalAgents: Protective - Talc-zinc oxide-calamine-zinc stearate-titanium dioxide-
kaolin- silicon polymers and Dimethicone. Astringents - Alum- zinc sulfate and zinc
chloride. Antimicrobials Hydrogen peroxide-potassium permanganate-chlorinated lime-
iodine- boric acid- silver nitrate- sodium stilbogluconate- povidone-iodine- selenium sulfide
and zinc undecenoate.

8
 TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Text Book of
1 V.N Rajasekaran pharmaceutical Sun Publications 2005
Inorganic Chemistry

REFERENCES:

S. AUTHOR(S) YEAR OF
TITLE OF THE BOOK PUBLISHER
No NAME PUBLICATION
Pharmaceutical Inorganic
[Link]
1 [Link] chemistry 2007

Surendra N.
A text book Inorganic
2 Pandeya Sg Publisher 2011
medicinal chemistry

Inorganic Pharmaceutical Himalaya Pub.

3 Anand & Chatwal Chemistry House 2010
Press of IPC under
The Indian
Ministry of Health
4 Pharmacopoeia 1996
Indian Pharmacopoeia & Family Welfare,
Commission
Govt. of India

WEBSITES:

[Link]
[Link]
[Link]

9
 15PYUG112 PHARMACEUTICAL INORGANIC CHEMISTRY I 0032100
(PRACTICAL)
1. Limit test for Chloride
2. Limit test for Sulphate
3. Limit test for Iron
[Link] of Barium sulphate
[Link] of Magnesium sulphate
[Link] of Boric acid
[Link] for acid neutralizing capacity of Aluminium hydroxide gel
[Link] for adsorption power in heavy kaolin
[Link] qualitative analysis for unknown inorganic mixture (four experiments)

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE PUBLISHER YEAR OF

No NAME BOOK PUBLICATION
Text Book of
1 V.N Rajasekaran pharmaceutical Sun Publications 2005
Inorganic Chemistry

REFERENCES:

S. AUTHOR(S) TITLE OF THE PUBLISHER YEAR OF

No NAME BOOK PUBLICATION
The Indian Press of IPC under
Indian Pharmacopoeia 1996
1 Pharmacopoeia Ministry of Health
Commission & Family Welfare,
Govt. of India

10
15PYUG103 PHARMACEUTICAL ORGANIC CHEMISTRY I 3003100
(THEORY)
OBJECTIVES:
Illuminate relevance & significance of Organic Chemistry to Pharmaceutical Sciences.
Review and study fundamentals of Organic Chemistry in identifying and synthesizing organic
compounds essentially employed as drugs and pharmaceuticals.
Clarify basic principles concepts of organic chemistry
Explain basic functional groups & IUPAC Nomenclature of Organic Compounds.

INTENDED OUTCOMES:

Students undergoing this able to

Explain different Reaction Intermediates & their application in reaction mechanism.

How to name the organic compounds
Explain different reaction involve in the formation of aromatic compounds.

Unit I
Molecular orbital theory- wave equations- molecular orbitals- bonding- anti-bonding orbitals-
unshared pair of electrons and hybrid orbitals. Intra-molecular and inter-molecular forces-
their effect on solubility- boiling point- melting point-covalent bond- polarity of bond-
polarity of molecule- dipole moment- bond dissociation energy- energy of activation-
solubility of ionic solutesandnonionicsolutes.

Unit II
Inductive effect- electromeric effect- mesomeric effect- resonance effect- resonance-
tautomerism- conjugation- hyperconjugation- types of bond fission- electrophiles and
nucleophiles. IUPAC nomenclature of organic compounds.

Unit III
Mechanism of halogenations of alkanes- SP3 Hybridization in alkanes- stabilities of alkenes-
SP2 Hybridization in alkenes-thermodynamics and kinetics of the reactions of methane with
a halogen- Saytzeffs rule-free radical and electrophilic addition on C=C bond-
Markownikoffs rule- Peroxide effect- Ozonolysismechanism of Diels - Alder reaction
and addition reaction of conjugated dienes.

11
 Unit IV
Bayers strain theory- Limitations of Bayers strain theory- Coulson and Moffitts
modification- Sachse Mohrs theory( Theory of strain less rings).

Unit V
Derivation of structure of benzene- Kekule structure- heat of hydrogenation and stability- C-
C bond length in benzene- Resonance structure of benzene-orbital picture- aromatic
character- Huckels rule-Mechanism of electrophilic and nucleophilic aromatic substitution-
reaction. Theory of effect of substituent on reactivity and orientation- Preparation and
reactions of benzene including Friedel crafts alkylation and acylation.

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Arun Bahl and Advanced Organic [Link] 2012
1 [Link] Chemistry

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 E.I. Elliel. Stereo Chemistry of Organic Wiley Eds 1988
Compounds
Cramand Hammered Organic chemistry Pine 2005
2 Hendrickson
Advanced Organic
3 Jerry March Chemistry: Reactions, Wiley: New 1992
Mechanisms, and York, NY
Structure

WEBSITES:
[Link]
[Link]
[Link]
12
 15PYUG113 PHARMACEUTICAL ORGANIC CHEMISTRY I 0032100
(PRACTICAL)

1. Preparation of Salicyclic acid

2. Preparation of Benzamide
3. Preparation of Iodoform
4. Preparation of Phenyl Benzoate
5. Preparation of Dibenzilidine acetone
6. Assay of organic compounds involving acidimetry, alkalimetry (at least 02).
7. Melting point of any synthesized compound
8. Stereo models
9. Systematic qualitative analysis of organic compounds including preparation of derivative
(not less than 4 compounds with different functional groups).

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Practical Organic Dorling 2008
1 Arthur I Vogel Chemistry by vogel Kindersley

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Brian Furniss, Antony Vogels Text Book of ELBS Publication, 1997
1 Hannaford, Peter Practical Organic Singapore
Smith, Austrin Chemistry

13
15PYUG104 PHARMACOGNOSY AND PHYTO CHEMISTRY I 3003100
(THEORY)
OBJECTIVES:
To learn and understand the cultivation and production of crude drugs and their
usefulness.

INTENDED OUTCOMES:

Students undergoing this able to

Know the advances in the cultivation and production of drugs

Know the evaluation techniques for the herbal drugs.

Unit I
Definition-History-Present status-Future scope-Development of Pharmacognosy

Unit II
Alphabetical- Biological- Chemical- Pharmacological- Taxonomical- Chemotaxonomicial
and Serotaxonomical

Unit III
General principles of cultivation & collection of vegetable drugs of commercial
Significance from wild & cultivated source-Advantage and disadvantages of cultivation- Soil
and soil fertility- Factors influencing cultivation of medicinal plants- Processing- storage- and
preservation of crude drugs- Study of natural pesticides.

Unit IV
Different methods of adulteration of crude drugs & their detection by evaluation
methods. Introduction- morphological-Microscopical- physical- chemical- biological and
spectral analysis of herbal drugs

Unit V
Detailed study of crude drugs with emphasis on source- cultivation- collection- preparation-
storage- diagnostic characters (Macroscopic & Microscopic techniques applied)-
constituents- chemical tests- substitutes- adulterants & uses of:

14
Carbohydrates and their derived products: Agar- Gum Acacia- Gum tragacanth- Honey-
Isapgol- pectin- Starch-Tannins: Gambier- Black Catechu- Gall- Myrobalan- Pale catechu
and Tannic acid-Lipids: Castor oil- Shark liver oil- Wool fat- Beeswax- Neem oil- Cod liver
oil and Bran oil. Proteins: Gelatin- Spirullina and soyaVolatile oils: Mentha- Coriander-
Cinnamon- Cassia- Caraway- Dill- Clove- Fennel- Nutmeg- Cardamom- Lemon grass oil-
Eucalyptus- Sandalwood- Palmarosa and Citronellal. Saponins: Liquorice- Ginseng-
Dioscorea. Cardio active sterols: Digitalis- Squill and Strophanthus- Steroidal: Kurchi-
Solasodine. Alkaloidal amines: Ephedra and Colchicum- Glycoalkaloids: Solanum species.

TEXT BOOKS:

S. AUTHOR(S) YEAR OF
TITLE OF THE BOOK PUBLISHER
No NAME PUBLICATION
Kokate C.K-
Purohit A.P- Text book of Pharmacognosy
1 Nirali prakasan 2008
Gokhale S.B

REFERENCES:

S. AUTHOR(S) YEAR OF
TITLE OF THE BOOK PUBLISHER
No NAME PUBLICATION

1 Trease and Evans Pharmacognosy W.B Sauders 2002

James Robbers-
Marilyn K.
Pharmacognosy and Williams and
2 Speedice and 1996
Pharmacobiotechnology Wilkins
Varro E.- Tyler
CBS publishers
and
TE Wallis Textbook of
3 Distributors- 2005
Pharmacognosy
New Delhi

15
WEBSITES:
[Link]
[Link]
[Link]

16
15PYUG114 PHARMACOGNOSY AND PHYTO CHEMISTRY I 0032100
(PRACTICAL)

1. Identification of crude drugs listed in theory (entire condition) by Morphological

characters.
2. Microscopical studies of some selected drugs:
Datura- Digitalis- Cinnamon- Clove- Ephedra- Liquorice- Fennel- Coriander.
3. Microscopical studies of some selected powdered drugs of single component or mixture of
two components:
Datura- Cinnamon- Digitalis- Ipecac- Clove- Fennel- Coriander.

4. Identification of unorganized drugs by Morphological characters and chemical tests.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
[Link] and Practical Pharmacognosy Vallabh 2008
1 C.K kokate prakasan

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Khandelwal KR Practical pharmacognosy Nirali 2005
prakashan

17
15PYUG105 BIOSTATISTICS & COMPUTER APPLICATIONS-I 3003100
(THEORY)
OBJECTIVES:
To learn and understand the computer basics
To learn the statistical method of analysis that can apply in the development and use of
therapeutic drug.

INTENDED OUTCOMES:Students undergoing this able to

Able to organize, summarize, and display quantitative data.

Comfortable with statistical methods for calculating summary estimates, measures of
variability, and confidence intervals.

Unit I
Application of biostatics in medicine and pharmacy- collection of data: classification and
tabulation of statistical data- diagrammatic and graphical representation- measure of central
tendancy. Mean Median- mode geometric Mean

Unit II
Purpose of sampling- methods of sampling- test significance- Null hypothesis and alternative
hypothesis- standard errors-one tailed test and two tailed test-T test

Unit III
Correlation analysis- application of correlation analysis- types of correlation-Scatter diagram-
karlpearsons correlation coefficient- spearmans rank correlation coefficient

Unit IV
Computer application: Basic computer components of organization- classification of
computers- binary number system conversion- types of memory device- network topology:
types of computer networks- internet search engine- computer input and output device-
multimedia- MS office package- advantages and application.

Unit V
Types of computer software and application- types of operating systems: statistical software
tools- DBMS and RDDMS- data abstraction- E- R diagram concept- Client server process-
network layers- HTML web pages

18
TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Hunt N and Computers and commonsense Prentice Hall 1998
Shelly J of India, New
Delhi.

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Popst and Perrum Computer aided drug design Academic 2007
Press, New
York
2 Writh Systematic programming an Prentice hall 2006
introduction Englewood
Cliffs New
Jersey
3 Tanen Baum Computer networks Pearson
education 1993
[Link]
4 S.C Gupta Fudamentals of statistics Pushpa banarje 2000
5 D.N Elhance and Practical Problems in Century printers 1955
Veen Elhance statistics
6 Y.I Shah, Introduction to biostatics Prentice /Hall 2006
[Link] & and computer science of india
[Link]
7 P.S.S Sunder Rao Introduction tom biostatics Prentice /Hall 2009
and [Link] and research of india

WEBSITES:
[Link]
[Link]
[Link]

19
15PYUG115 BIOSTATISTICS & COMPUTER APPLICATIONS - I 0032100
PRACTICAL

1. Computer operating systems like MS DOS etc

2. Simple program in C
3. MS office (MS-Word, MS-Excel, M S- power point).

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Johnathan Microsoft office 2010 In Kogent lerning 2011
Lightfoot, chris simple steps solutions
Beckett0

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Margret Levine Complete reference internet Osborne/ 2007
Young McGraw-Hill

20
 SYLLABUS FOR
B. PHARMACY DEGREE COURSE (2015 2016)

SEMESTER II

[Link] TITLE OF THE COURSE L T P C CIA ESE TOTAL

THEORY
15PYU201 Human Anatomy, Physiology & Health 3 0 0 3 40 60 100
Education -II
15PYU202 Pharmaceutical Inorganic Chemistry-II 3 0 0 3 40 60 100
15PYU203 Pharmaceutical Organic Chemistry-II 3 0 0 3 40 60 100
15PYU204 Pharmacognosy & Phytochemistry-II 3 0 0 3 40 60 100
15PYU205 Biostatistics & Computer Applications-II 3 0 0 3 40 60 100
PRACTICAL
15PYU211 Human Anatomy, Physiology &Health 0 0 3 2 40 60 100
Education -II
15PYU212 Pharmaceutical Inorganic Chemistry-II 0 0 3 2 40 60 100
15PYU213 Pharmaceutical Organic Chemistry-II 0 0 3 2 40 60 100
15PYU214 Pharmacognosy and Phytochemistry-II 0 0 3 2 40 60 100
15PYU215 Biostatistics & Computer Applications-II 0 0 3 2 40 60 100
TOTAL 15 0 15 25 400 600 1000
TOTAL CONTACT HOURS/WEEK 30

21
 15PYUG201 HUMAN ANATOMY- PHYSIOLOGY AND 3003100
HEALTH EDUCATION II THEORY
OBJECTIVES:
This subject is designed to impart fundamental knowledge on the structure and
functions of the various systems of the human body.
It also helps in understanding both homeostatic mechanisms and homeostatic
imbalances of various systems of the body.
Since a medicament- which is produced by the pharmacist- is used in various disease
conditions to correct the abnormal functioning of the body systems- the basic
knowledge of this subject is must for a student to understand how drugs act on various
systems/organs in correcting the disease state of organs/systems.
Thus it becomes a prerequisite subject for the pharmacy course.

INTENDED OUTCOMES:

Students undergoing this able to

Understand the gross morphology- structure and functions of various organs of the
human body.
Understand the various homeostatic mechanisms and their imbalances
Identify the various tissues and organs of different systems of the human body.
Perform the hematological tests like blood cell counts- hemoglobin estimation-
bleeding/clotting time- etc and also record blood pressure- ECG- heart rate- pulse and
respiratory volume.
Appreciate coordinated working pattern of different organs of each system
Appreciate the interlinked mechanisms in the maintenance of normal functioning
(homeostasis) of the human body.

Unit - I
Endocrine system- Basic anatomy and physiology of pituitary-thyroid-parathyroid-adrenal
and pancreatic hormones and disorders of these glands.

22
Unit II
Reproductive system- Structure and functions of male and female reproductive systems.
Sex hormones- physiology of menstruation- coitus and fertilization. Spermatogenesis and
oogenesis-pregnancy and parturition- oral contraceptives.

Unit III
Central Nervous system- Structure and functions of brain and spinal cord. Functions of
cerebrum-cerebellum- vital centers of medulla oblongata- cerebral ventricles- cranial nerves
and their functions. Reflex arc- cerebrospinal fluid and its functions- meningitis.

Unit IV
Autonomic nervous system- Anatomy- physiology and divisions of [Link] and
sensory pathways.

Unit V
Sense organs- Physiology of vision- audition-olfaction- taste and skin. Health education
and Nutrition- Concepts of health and disease- Disease causing agents and prevention of
disease. Balanced diet-deficiency disorders of various nutrients-their prevention and
treatment.
Communicable disease- The causative agents-modes of transmission and prevention of
chicken pox-measles-diphtheria- tuberculosis- malaria- poliomyelitis- filariasis- rabies-
tetanus- STD and AIDS. Vaccination schedule. Emergency treat ment of shock-
snakebite- burns-poisoning-fracturesand resuscitation methods. First Aid.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Ross and Wilson Churchill
1 Anne Waug and Anatomy and Physiology Livingstone 2013
Allison Grant in Health and illness Elsevier-UK

23
REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Human Physiology-Vol. Medical Allied
1 [Link] I & II Agency-Calcutta 1997

2 Gerard J Tortora- Principles of Anatomy Wiley-USA 2014

Bryan Derrickson and Physiology
3 Cinnamon Van Seeleys Fundamentals of TataMc
Putte Human Anatomy and Graw Hill-New 2009
Physiology Delhi

WEBSITES:
[Link]
[Link]
[Link]

24
15PYUG211 HUMAN ANATOMY, PHYSIOLOGY AND HEALTH 0032100
EDUCATION I (PRACTICAL)
15PYUG211
PRACTICALS
1. Determination of blood count
2. Determination of differential leukocyte count
3. Recording of systematic arterial blood pressure
4. Determination of heart rate
5. Identification of tissues
6. Identification of bones
7. Experimental models
8. Health education

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Godkar P.B and Textbook of Medical Bhalani Publishing
1 Godkar D.P Laboratory Technology House, Mumbai 2007

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Tata McGraw Hill
1 Mukherjee, K.L Medical Laboratory Publishing 2010
Technology Company Ltd. New
Delhi

25
15PYUG202 PHARMACEUTICAL INORGANIC CHEMISTRY II
3003100
THEORY
OBJECTIVES:
The organic chemistry section deals with classification andnomenclature of organic
compounds- structural isomerism- intermediates formed in reactions- important
physical properties- reactions and methods of preparation of compounds.
The syllabus also emphasizes on mechanisms and orientation of reactions.
The analytical chemistry section designed to enable the students to have fundamental
knowledge of volumetric analysis and determination of impurities in Pharmaceuticals.

INTENDED OUTCOMES:
Students undergoing this able to

Write the structure- name- type of isomerism of the organic compound

Write the reaction- name the reaction and understand the orientation of reactions
Account for reactivity/stability of compounds-+
Identify/confirm the organic compound
Know the principle of volumetric analysis of drugs.

Unit-I
Anti-caries Agents: Role of fluorides as anti-caries agents-sodiumfluoride. Dentifrices-
Calciumcarbonate- dibasic calcium phosphate- strontium chloride- zincs chloride. Medicinal
Gases- Oxygen- carbon dioxide- helium- nitrogen and nitrous oxide.

Unit -II
Major intra and extra cellular electrolytes- Physiological role of chloride-phosphate-
bicarbonate-sodium-potassium-calcium and magnesium. Electrolytes used for replacement
therapy: Sodium chloride-potassium chloride-calcium chloride- calcium gluconate- calcium
lactate- dibasic calcium phosphate- tribasic calcium phosphate. Physiological acid-base
balance and its importance. Electrolytes use dintheacid- basetherapy: Sodium acetate-
potassium acetate-sodium bicarbonate-potassium bicarbonate-sodium citrate-sodium lactate-
ammonium chloride. Electrolyte combination therapy- compound sodium chloride solution-
sodium chloride injection and oral rehydration salt.

26
 Unit III
Essential and Trace ions- Definition- physiological role of iron- copper- zinc- chromium-
manganese-molybdenum-selenium-sulphur and iodine.
Ferrous fumarate- ferrous gluconate- ferrous sulphate- iron and ammonium citrate. Official
formulation: Iron dextran injection- strong iodine solution.

Unit IV
Pharmaceutical Aids- Sodium bisulphite- sodium metabisulphite- sulphurdioxide-
bentonite-magnesium stearate - zinc stearate- aluminium sulphate- sodium carboxy methyl
cellulose-sodium formaldehyde sulphoxylate- purified water- water for injection and sterile
water for injection.

Unit V
Miscellaneous- Sclerosing agents: Hypertonic saline- sodium tetradecyl sulphate.
Expectorants: Potassium citrate and potassium iodide. Sedative: Potassium bromide.
Antidotes: Sodium nitrite- sodium thiosulphate and charcoal. Respiratory stimulant:
Ammonium carbonate.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Text Book of
1 V.N Rajasekaran pharmaceutical Sun Publications 2005
Inorganic Chemistry

27
REFERENCES:

S. AUTHOR(S) YEAR OF
TITLE OF THE BOOK PUBLISHER
No NAME PUBLICATION
Pharmaceutical Inorganic
[Link]
1 [Link] chemistry 2007

Surendra N.
A text book Inorganic
2 Pandeya Sg Publisher 2011
medicinal chemistry

Inorganic Pharmaceutical Himalaya Pub.

3 Anand & Chatwal Chemistry House 2010

WEBSITES:

[Link]
[Link]
[Link]

28
 15PYUG212 PHARMACEUTICAL INORGANIC CHEMISTRY I 0032100
(PRACTICAL)

1. Modified limit test for chloride in KMnO4

2. Modified limit test for Sulphate in KMnO4
3. Modified limit test for chloride in NaHCO3
4. Modified limit test for Sulphate in NaHCO3
5. Preparation of Calcium Carbonate
6. Preparation of Zinc Oxide
7. Preparation of Potassium citrate
8. Test for Swelling power of bentonite
9. Test for Presence of iodate in potassium iodide
10. Systematic qualitative salt analysis (4 compounds)

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Text Book of
V.N Rajasekaran pharmaceutical Sun Publications 2005
1
Inorganic Chemistry

REFERENCES:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Press of IPC under
The Indian
Ministry of Health
Pharmacopoeia 1996
1 Indian Pharmacopoeia & Family Welfare,
Commission
Govt. of India

29
15PYUG203 PHARMACEUTICAL ORGANIC CHEMISTRY -II 3003100
THEORY
OBJECTIVES:
Illuminate relevance & significance of Organic Chemistry to Pharmaceutical Sciences.
Review and study fundamentals of Organic Chemistry in identifying and synthesizing organic
compounds essentially employed as drugs and pharmaceuticals.
Clarify basic principles concepts of organic chemistry
Explain basic functional groups & IUPAC Nomenclature of Organic Compounds.

INTENDED OUTCOMES:

Students undergoing this able to

Explain different Reaction Intermediates & their application in reaction mechanism.

How to name the organic compounds
Explain different reaction involve in the formation of aromatic compounds.

Unit I
Preparation and properties of polyaromatic compounds- Naphthalene- anthracene-
phenanthrene- iphenylmethane- triphenylmethane and diphenylethane. Preparation- test for
purity and medicinal uses of dicophane- gammaxene- saccharin- methyl salicylate-
phenindione-ethylbiscoumacetate- vanillin- urethane- carbromal- amphetamine and
acetanilide.

Unit II
General structure- nomenclature- preparation and reaction mechanism of alkyl and
aryl halides- (Mechanism of SN1-SN2, E1 and E2)

Unit III
Alcohols- ethers- epoxides- amines (basicity of amines- influence of substitutent on basic
property)- aldehydes- ketones- carboxylic acids and functional derivatives of carboxylic
acids.

30
 Unit IV
Preparation-test for purity and medicinal uses of Chloroform- Iodoform- Mephenesin- Citric
acid- Lactic acid- Benzoic acid-Sodium lauryl sulphate and Glycol.

Unit V
Reactive intermediates- Carbocations -Carbanions- Carbenes- Free radicals generation-
relative stability- fate and applications. Properties of Alpha () and Beta () unsaturated
carbonyl compounds. Preparation and synthetic utility of aceto-acetic ester-malonic ester-
Grignard reagent and diazonium salts.

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Arun Bahl and Advanced Organic [Link] 2012
1 [Link] Chemistry

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 E.I. Elliel. Stereo Chemistry of Organic Wiley Eds 1988
Compounds
Cramand Hammered Organic chemistry Pine 2005
2 Hendrickson
Advanced Organic
3 Jerry March Chemistry: Reactions, Wiley: New 1992
Mechanisms, and York, NY
Structure

31
WEBSITES:
[Link]
[Link]
[Link]

32
 15PYUG213 PHARMACEUTICAL ORGANIC CHEMISTRY I 0032100
(PRACTICAL)

1. Determination of melting point and boiling point of organic compounds including

mixed melting point technology (3 compounds)
2. Preparation of organic compounds (5 compounds)
3. Systematic Qualitative Salt analysis (4 compounds)

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Practical Organic Dorling 2008
1 Arthur I Vogel Chemistry by Vogel Kindersley

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Brian Furniss, Antony Vogels Text Book of ELBS Publication, 1997
1 Hannaford, Peter Practical Organic Chemistry Singapore
Smith, Austrin

33
15PYUG204 PHARMACOGNOSY AND PHYTOCHEMISTRY II 3003100
THEORY
OBJECTIVES:
To learn and understand the cultivation and production of crude drugs and their
usefulness.

INTENDED OUTCOMES:

Students undergoing this able to

Know the advances in the cultivation and production of drugs

Know the evaluation techniques for the herbal drugs.

Unit I
Detailed study of crude drugs with emphasis on source- cultivation- collection-
preparation- storage- diagnostic characters (Macroscopic & Microscopic techniques
applicable)- constituents- chemical tests- substitutes- adulterants & uses of-
Anthraquinone cathartics: Aloes- Senna- Rhubarb and Cascara. Pyridine and Piperidine
alkaloids: Areca and [Link] alkaloids: Belladona- Hyoscyamus- Datura- Cocoa.
Quinoline and Isoquinoline alkaloids: Cinchona- Ipecac and Opium Indole alkaloids: Ergot-
Rauwolfia- Nuxvomica- Physostigmine. Imidazole: Pilocarpus.

Unit II
Purines: Tea-Coffee. Resins: Colophony- Cannabis- Capsicum- Balsam of Tolu-Benzoin-
Balsam of Peru- Asafoetida- Turmeric and Ginger. Quinazolidine alkaloids: Adathoda
Terpenes: Neem-Artemesia. Others: Gentian- Saffron- Ashwagandha

Unit III
Tumor inhibitors- Taxol- Vinca and Podophyllum

Unit IV
Anti-hepatotoxic and oral hypoglycemic agents Phyllanthusniruri- Eclipta Alba-
Gymnema sylvestre.

34
Unit V
Plant fibers used as surgical dressing- Cotton- Silk- Wool- Nylon- Rayon- Alginate
dressing- Gelatin Sponge- Oxidized cellulose. Sutures and ligatures.
Pharmaceutical aid - Talc- Kaolin-Bentonite and Natural colours.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Kokate C.K- Text book of Pharmacognosy
1 Purohit A.P- Nirali prakasan 2008
Gokhale S.B
REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION

1 Trease and Evans Pharmacognosy W.B Sauders 2002

James Robbers-
2 Marilyn K. Pharmacognosy and Williams and 1996
Speedice and Pharmacobiotechnology Wilkins
Varro E.- Tyler
CBS publishers
3 TE Wallis Textbook of and 2005
Pharmacognosy Distributors-
New Delhi

WEBSITES:
[Link]
[Link]
[Link]

35
 15PYUG214 PHARMACOGNOSY AND PHYTO CHEMISTRY I 0032100
(PRACTICAL)

1. Microscopical studies of some selected drugs:

Senna- Vinca- Cinchona- Nuxvomica- Ephedra- Rauwolfia- Ipecac- Ginger- Neem-
Phyllanthus
2. Microscopical studies of some selected powdered drugs of single component or
mixture of two components:
Cinchona- Senna -Rauwolfia- Ipecac- Nuxvomica- Rhubarb- Neem- Phyllanthus-
Ginger
3. Quantitative microscopy:
Microscopical measurements of cells and cell contents: Starch grains, calcium
oxalate crystals and phloem fibres.
Determination of leaf constants i.e.,stomatalindex, stomatal number,vein islet
number, vein termination number and palisade ratio.
Lycopodium spore method.

4. To do simple chemical tests to identify the pharmaceutically important

phytoconstituents based on the theory.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
[Link] and Practical Pharmacognosy Vallabh 2008
1 C.K kokate prakasan

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Khandelwal KR Practical pharmacognosy Nirali 2005
prakashan

36
15PYUG205 BIO-STATISTICS AND COMPUTERAPPLICATIONS-II 3003100
THEORY
OBJECTIVES:
To learn and understand the cultivation and production of crude drugs and their
usefulness.

INTENDED OUTCOMES:

Students undergoing this able to

Able to organize, summarize, and display quantitative data.

Comfortable with statistical methods for calculating summary estimates, measures of
variability, and confidence intervals.

Unit I
Bio-statistics-Dispersion-Theory of sampling. Statistical inference.

Unit II
Regression and correlation. Probabilities.

Unit III
Computer Packages- MS Office. MS Word-MS ExcelMSPowerPointAdvantages and use.

Unit IV
Introduction to Computer Networks- [Link]-
WorldWideWeb.

Unit V
Computer Graphics - Definition-displaydevices-graphicalinputandoutputdevices-
multimediadefinitionand application.

37
TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Hunt N and Computers and commonsense Prentice Hall 1998
Shelly J of India, New
Delhi.

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Popst and Perrum Computer aided drug design Academic 2007
Press, New
York
2 Writh Systematic programming an Prentice hall 2006
introduction Englewood
Cliffs New
Jersey
3 Tanen Baum Computer networks Pearson
education 1993
[Link]
4 S.C Gupta Fudamentals of statistics Pushpa banarje 2000
5 D.N Elhance and Practical Problems in Century printers 1955
Veen Elhance statistics
6 Y.I Shah, Introduction to biostatics Prentice /Hall 2006
[Link] & and computer science of india
[Link]
7 P.S.S Sunder Rao Introduction tom biostatics Prentice /Hall 2009
and [Link] and research of india

WEBSITES:
[Link]
[Link]
[Link]

38
15PYUG215 BIOSTATISTICS & COMPUTER APPLICATIONS - I 0032100
(PRACTICAL)

1. Computer operating systems like MS DOS, etc.

2. Simple programin C.
3. MS Office (MS-Word, MS-Excel,MS-Access,MS-Powerpoint).

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Johnathan Microsoft office 2010 In Kogent lerning 2011
Lightfoot, chris simple steps solutions
Beckett0

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Margret Levine Complete reference internet Osborne/ 2007
Young McGraw-Hill

39
 SYLLABUS FOR
B. PHARMACY DEGREE COURSE (2015 2016)

SEMESTER II

[Link] TITLE OF THE COURSE L T P C CIA ESE TOTAL

THEORY
15PYU201 Human Anatomy, Physiology & Health 3 0 0 3 40 60 100
Education -II
15PYU202 Pharmaceutical Inorganic Chemistry-II 3 0 0 3 40 60 100
15PYU203 Pharmaceutical Organic Chemistry-II 3 0 0 3 40 60 100
15PYU204 Pharmacognosy & Phytochemistry-II 3 0 0 3 40 60 100
15PYU205 Biostatistics & Computer Applications-II 3 0 0 3 40 60 100
PRACTICAL
15PYU211 Human Anatomy, Physiology &Health 0 0 3 2 40 60 100
Education -II
15PYU212 Pharmaceutical Inorganic Chemistry-II 0 0 3 2 40 60 100
15PYU213 Pharmaceutical Organic Chemistry-II 0 0 3 2 40 60 100
15PYU214 Pharmacognosy and Phytochemistry-II 0 0 3 2 40 60 100
15PYU215 Biostatistics & Computer Applications-II 0 0 3 2 40 60 100
TOTAL 15 0 15 25 400 600 1000
TOTAL CONTACT HOURS/WEEK 30

40
15PYUG201 HUMAN ANATOMY- PHYSIOLOGY AND
3003100
HEALTH EDUCATION II THEORY
OBJECTIVES:
This subject is designed to impart fundamental knowledge on the structure and
functions of the various systems of the human body.
It also helps in understanding both homeostatic mechanisms and homeostatic
imbalances of various systems of the body.
Since a medicament- which is produced by the pharmacist- is used in various disease
conditions to correct the abnormal functioning of the body systems- the basic
knowledge of this subject is must for a student to understand how drugs act on various
systems/organs in correcting the disease state of organs/systems.
Thus it becomes a prerequisite subject for the pharmacy course.

INTENDED OUTCOMES:

Students undergoing this able to

Understand the gross morphology- structure and functions of various organs of the
human body.
Understand the various homeostatic mechanisms and their imbalances
Identify the various tissues and organs of different systems of the human body.
Perform the hematological tests like blood cell counts- hemoglobin estimation-
bleeding/clotting time- etc and also record blood pressure- ECG- heart rate- pulse and
respiratory volume.
Appreciate coordinated working pattern of different organs of each system
Appreciate the interlinked mechanisms in the maintenance of normal functioning
(homeostasis) of the human body.

41
Unit - I
Endocrine system- Basic anatomy and physiology of pituitary-thyroid-parathyroid-adrenal
and pancreatic hormones and disorders of these glands.

Unit II
Reproductive system- Structure and functions of male and female reproductive systems.
Sex hormones- physiology of menstruation- coitus and fertilization. Spermatogenesis and
oogenesis-pregnancy and parturition- oral contraceptives.

Unit III
Central Nervous system- Structure and functions of brain and spinal cord. Functions of
cerebrum-cerebellum- vital centers of medulla oblongata- cerebral ventricles- cranial nerves
and their functions. Reflex arc- cerebrospinal fluid and its functions- meningitis.

Unit IV
Autonomic nervous system- Anatomy- physiology and divisions of [Link] and
sensory pathways.

Unit V
Sense organs- Physiology of vision- audition-olfaction- taste and skin. Health education
and Nutrition- Concepts of health and disease- Disease causing agents and prevention of
disease. Balanced diet-deficiency disorders of various nutrients-their prevention and
treatment.
Communicable disease- The causative agents-modes of transmission and prevention of
chicken pox-measles-diphtheria- tuberculosis- malaria- poliomyelitis- filariasis- rabies-
tetanus- STD and AIDS. Vaccination schedule. Emergency treat ment of shock-
snakebite- burns-poisoning-fracturesand resuscitation methods. First Aid.

42
TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Ross and Wilson Churchill
1 Anne Waug and Anatomy and Physiology Livingstone 2013
Allison Grant in Health and illness Elsevier-UK

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Human Physiology-Vol. Medical Allied
1 [Link] I & II Agency-Calcutta 1997

2 Gerard J Tortora- Principles of Anatomy Wiley-USA 2014

Bryan Derrickson and Physiology
3 Cinnamon Van Seeleys Fundamentals of TataMc
Putte Human Anatomy and Graw Hill-New 2009
Physiology Delhi

WEBSITES:
[Link]
[Link]
[Link]

43
15PYUG211 HUMAN ANATOMY, PHYSIOLOGY AND HEALTH 0032100
EDUCATION II (PRACTICAL)
15PYUG211
PRACTICALS
9. Determination of blood count
10. Determination of differential leukocyte count
11. Recording of systematic arterial blood pressure
12. Determination of heart rate
13. Identification of tissues
14. Identification of bones
15. Experimental models
16. Health education

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Godkar P.B and Textbook of Medical Bhalani Publishing
1 Godkar D.P Laboratory Technology House, Mumbai 2007

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Tata McGraw Hill
1 Mukherjee, K.L Medical Laboratory Publishing 2010
Technology Company Ltd. New
Delhi

44
15PYUG202 PHARMACEUTICAL INORGANIC CHEMISTRY II
3003100
THEORY
OBJECTIVES:
The organic chemistry section deals with classification andnomenclature of organic
compounds- structural isomerism- intermediates formed in reactions- important
physical properties- reactions and methods of preparation of compounds.
The syllabus also emphasizes on mechanisms and orientation of reactions.
The analytical chemistry section designed to enable the students to have fundamental
knowledge of volumetric analysis and determination of impurities in Pharmaceuticals.

INTENDED OUTCOMES:
Students undergoing this able to

Write the structure- name- type of isomerism of the organic compound

Write the reaction- name the reaction and understand the orientation of reactions
Account for reactivity/stability of compounds-+
Identify/confirm the organic compound
Know the principle of volumetric analysis of drugs.

Unit-I
Anti-caries Agents: Role of fluorides as anti-caries agents-sodiumfluoride. Dentifrices-
Calciumcarbonate- dibasic calcium phosphate- strontium chloride- zincs chloride. Medicinal
Gases- Oxygen- carbon dioxide- helium- nitrogen and nitrous oxide.

Unit -II
Major intra and extra cellular electrolytes- Physiological role of chloride-phosphate-
bicarbonate-sodium-potassium-calcium and magnesium. Electrolytes used for replacement
therapy: Sodium chloride-potassium chloride-calcium chloride- calcium gluconate- calcium
lactate- dibasic calcium phosphate- tribasic calcium phosphate. Physiological acid-base
balance and its importance. Electrolytes use dintheacid- basetherapy: Sodium acetate-
potassium acetate-sodium bicarbonate-potassium bicarbonate-sodium citrate-sodium lactate-
ammonium chloride. Electrolyte combination therapy- compound sodium chloride solution-
sodium chloride injection and oral rehydration salt.
Unit III
Essential and Trace ions- Definition- physiological role of iron- copper- zinc- chromium-
45
 manganese-molybdenum-selenium-sulphur and iodine.
Ferrous fumarate- ferrous gluconate- ferrous sulphate- iron and ammonium citrate. Official
formulation: Iron dextran injection- strong iodine solution.

Unit IV
Pharmaceutical Aids- Sodium bisulphite- sodium metabisulphite- sulphurdioxide-
bentonite-magnesium stearate - zinc stearate- aluminium sulphate- sodium carboxy methyl
cellulose-sodium formaldehyde sulphoxylate- purified water- water for injection and sterile
water for injection.

Unit V
Miscellaneous- Sclerosing agents: Hypertonic saline- sodium tetradecyl sulphate.
Expectorants: Potassium citrate and potassium iodide. Sedative: Potassium bromide.
Antidotes: Sodium nitrite- sodium thiosulphate and charcoal. Respiratory stimulant:
Ammonium carbonate.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Text Book of
1 V.N Rajasekaran pharmaceutical Sun Publications 2005
Inorganic Chemistry

46
REFERENCES:

S. AUTHOR(S) YEAR OF
TITLE OF THE BOOK PUBLISHER
No NAME PUBLICATION
Pharmaceutical Inorganic
[Link]
1 [Link] chemistry 2007

Surendra N.
A text book Inorganic
2 Pandeya Sg Publisher 2011
medicinal chemistry

Inorganic Pharmaceutical Himalaya Pub.

3 Anand & Chatwal Chemistry House 2010

WEBSITES:

[Link]
[Link]
[Link]

47
 15PYUG212 PHARMACEUTICAL INORGANIC CHEMISTRY II 0032100
(PRACTICAL)

11. Modified limit test for chloride in KMnO4

12. Modified limit test for Sulphate in KMnO4
13. Modified limit test for chloride in NaHCO3
14. Modified limit test for Sulphate in NaHCO3
15. Preparation of Calcium Carbonate
16. Preparation of Zinc Oxide
17. Preparation of Potassium citrate
18. Test for Swelling power of bentonite
19. Test for Presence of iodate in potassium iodide
20. Systematic qualitative salt analysis (4 compounds)

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Practical Harcourt Brace
A. H. Beckett and J.
Pharmaceutical College Publishers,
1 B. Stenlake 1998
chemistry Vol-I & II London

REFERENCES:

S. AUTHOR(S) TITLE OF THE YEAR OF

PUBLISHER
No NAME BOOK PUBLICATION
Press of IPC under
Indian
Ministry of Health
Pharmacopoeial 1996
1 Indian Pharmacopoeia & Family Welfare,
Commission
Govt. of India

48
15PYUG203 PHARMACEUTICAL ORGANIC CHEMISTRY -II
3003100
THEORY
OBJECTIVES:
Illuminate relevance & significance of Organic Chemistry to Pharmaceutical Sciences.
Review and study fundamentals of Organic Chemistry in identifying and synthesizing organic
compounds essentially employed as drugs and pharmaceuticals.
Clarify basic principles concepts of organic chemistry
Explain basic functional groups & IUPAC Nomenclature of Organic Compounds.

INTENDED OUTCOMES:

Students undergoing this able to

Explain different Reaction Intermediates & their application in reaction mechanism.

How to name the organic compounds
Explain different reaction involve in the formation of aromatic compounds.

Unit I
Preparation and properties of polyaromatic compounds- Naphthalene- anthracene-
phenanthrene- iphenylmethane- triphenylmethane and diphenylethane. Preparation- test for
purity and medicinal uses of dicophane- gammaxene- saccharin- methyl salicylate-
phenindione-ethylbiscoumacetate- vanillin- urethane- carbromal- amphetamine and
acetanilide.

Unit II
General structure- nomenclature- preparation and reaction mechanism of alkyl and
aryl halides- (Mechanism of SN1-SN2, E1 and E2)

Unit III
Alcohols- ethers- epoxides- amines (basicity of amines- influence of substitutent on basic
property)- aldehydes- ketones- carboxylic acids and functional derivatives of carboxylic
acids.

49
 Unit IV
Preparation-test for purity and medicinal uses of Chloroform- Iodoform- Mephenesin- Citric
acid- Lactic acid- Benzoic acid-Sodium lauryl sulphate and Glycol.

Unit V
Reactive intermediates- Carbocations -Carbanions- Carbenes- Free radicals generation-
relative stability- fate and applications. Properties of Alpha () and Beta () unsaturated
carbonyl compounds. Preparation and synthetic utility of aceto-acetic ester-malonic ester-
Grignard reagent and diazonium salts.

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Arun Bahl and Advanced Organic [Link] 2012
1 [Link] Chemistry

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 E.I. Elliel. Stereo Chemistry of Organic Wiley Eds 1988
Compounds
Cramand Hammered Organic chemistry Pine 2005
2 Hendrickson
Advanced Organic
3 Jerry March Chemistry: Reactions, Wiley: New 1992
Mechanisms, and York, NY
Structure

WEBSITES:
[Link]
[Link]
[Link]

50
 15PYUG213 PHARMACEUTICAL ORGANIC CHEMISTRY II
0032100
(PRACTICAL)

4. Determination of melting point and boiling point of organic compounds including

mixed melting point technology (3 compounds)
5. Preparation of organic compounds (5 compounds)
6. Systematic Qualitative Salt analysis (4 compounds)

TEXT BOOKS:
S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF
No NAME PUBLICATION
Practical Organic Dorling 2008
1 Arthur I Vogel Chemistry by Vogel Kindersley

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Brian Furniss, Antony Vogels Text Book of ELBS Publication, 1997
1 Hannaford, Peter Practical Organic Chemistry Singapore
Smith, Austrin

51
15PYUG204 PHARMACOGNOSY AND PHYTOCHEMISTRY II
3003100
THEORY
OBJECTIVES:
To learn and understand the cultivation and production of crude drugs and their
usefulness.

INTENDED OUTCOMES:

Students undergoing this able to

Know the advances in the cultivation and production of drugs

Know the evaluation techniques for the herbal drugs.

Unit I
Detailed study of crude drugs with emphasis on source- cultivation- collection-
preparation- storage- diagnostic characters (Macroscopic & Microscopic techniques
applicable)- constituents- chemical tests- substitutes- adulterants & uses of-
Anthraquinone cathartics: Aloes- Senna- Rhubarb and Cascara. Pyridine and Piperidine
alkaloids: Areca and [Link] alkaloids: Belladona- Hyoscyamus- Datura- Cocoa.
Quinoline and Isoquinoline alkaloids: Cinchona- Ipecac and Opium Indole alkaloids: Ergot-
Rauwolfia- Nuxvomica- Physostigmine. Imidazole: Pilocarpus.

Unit II
Purines: Tea-Coffee. Resins: Colophony- Cannabis- Capsicum- Balsam of Tolu-Benzoin-
Balsam of Peru- Asafoetida- Turmeric and Ginger. Quinazolidine alkaloids: Adathoda
Terpenes: Neem-Artemesia. Others: Gentian- Saffron- Ashwagandha

Unit III
Tumor inhibitors- Taxol- Vinca and Podophyllum

52
Unit IV
Anti-hepatotoxic and oral hypoglycemic agents Phyllanthusniruri- Eclipta Alba-
Gymnema sylvestre.

Unit V
Plant fibers used as surgical dressing- Cotton- Silk- Wool- Nylon- Rayon- Alginate
dressing- Gelatin Sponge- Oxidized cellulose. Sutures and ligatures.
Pharmaceutical aid - Talc- Kaolin-Bentonite and Natural colours.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
Kokate C.K- Text book of Pharmacognosy
1 Purohit A.P- Nirali prakasan 2008
Gokhale S.B
REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION

1 Trease and Evans Pharmacognosy W.B Sauders 2002

James Robbers-
2 Marilyn K. Pharmacognosy and Williams and 1996
Speedice and Pharmacobiotechnology Wilkins
Varro E.- Tyler
CBS publishers
3 TE Wallis Textbook of and 2005
Pharmacognosy Distributors-
New Delhi

WEBSITES:
[Link]
[Link]
[Link]
53
 15PYUG214 PHARMACOGNOSY AND PHYTO CHEMISTRY II
0032100
(PRACTICAL)

3. Microscopical studies of some selected drugs:

Senna- Vinca- Cinchona- Nuxvomica- Ephedra- Rauwolfia- Ipecac- Ginger- Neem-
Phyllanthus
4. Microscopical studies of some selected powdered drugs of single component or
mixture of two components:
Cinchona- Senna -Rauwolfia- Ipecac- Nuxvomica- Rhubarb- Neem- Phyllanthus-
Ginger
3. Quantitative microscopy:
Microscopical measurements of cells and cell contents: Starch grains, calcium
oxalate crystals and phloem fibres.
Determination of leaf constants i.e.,stomatalindex, stomatal number,vein islet
number, vein termination number and palisade ratio.
Lycopodium spore method.

4. To do simple chemical tests to identify the pharmaceutically important

phytoconstituents based on the theory.

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
[Link] and Practical Pharmacognosy Vallabh 2008
1 C.K kokate prakasan

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Khandelwal KR Practical pharmacognosy Nirali 2005
prakashan

54
15PYUG205 BIO-STATISTICS AND COMPUTERAPPLICATIONS-II
3003100
THEORY
OBJECTIVES:
To learn and understand the cultivation and production of crude drugs and their
usefulness.

INTENDED OUTCOMES:

Students undergoing this able to

Able to organize, summarize, and display quantitative data.

Comfortable with statistical methods for calculating summary estimates, measures of
variability, and confidence intervals.

Unit I
Bio-statistics-Dispersion-Theory of sampling. Statistical inference.

Unit II
Regression and correlation. Probabilities.

Unit III
Computer Packages- MS Office. MS Word-MS ExcelMSPowerPointAdvantages and use.

Unit IV
Introduction to Computer Networks- [Link]-
WorldWideWeb.

Unit V
Computer Graphics - Definition-displaydevices-graphicalinputandoutputdevices-
multimediadefinitionand application.

55
TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Hunt N and Computers and commonsense Prentice Hall 1998
Shelly J of India, New
Delhi.

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Popst and Perrum Computer aided drug design Academic 2007
Press, New
York
2 Writh Systematic programming an Prentice hall 2006
introduction Englewood
Cliffs New
Jersey
3 Tanen Baum Computer networks Pearson
education 1993
[Link]
4 S.C Gupta Fudamentals of statistics Pushpa banarje 2000
5 D.N Elhance and Practical Problems in Century printers 1955
Veen Elhance statistics
6 Y.I Shah, Introduction to biostatics Prentice /Hall 2006
[Link] & and computer science of india
[Link]
7 P.S.S Sunder Rao Introduction tom biostatics Prentice /Hall 2009
and [Link] and research of india

WEBSITES:
[Link]
[Link]
[Link]

56
15PYUG215 BIOSTATISTICS & COMPUTER APPLICATIONS - II 0032100
(PRACTICAL)

1. Computer operating systems like MS DOS, etc.

2. Simple programin C.
3. MS Office (MS-Word, MS-Excel,MS-Access,MS-Powerpoint).

TEXT BOOKS:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Johnathan Microsoft office 2010 In Kogent lerning 2011
Lightfoot, chris simple steps solutions
Beckett0

REFERENCES:

S. AUTHOR(S) TITLE OF THE BOOK PUBLISHER YEAR OF

No NAME PUBLICATION
1 Margret Levine Complete reference internet Osborne/ 2007
Young McGraw-Hill

57