Name: Kelompok P1
Exercise 9: Renal System Physiology: Activity 1: The Effect of Arteriole Radius on Glomerular Filtration Lab Report
Pre-lab Quiz Results
You scored 80% by answering 4 out of 5 questions correctly.
1. There are approximately __________ nephrons in a healthy human kidney.
You correctly answered: c. 1 106
2. Which of the following lists the anatomical structures in the correct order as they are encountered by the blood and
filtered fluid during the process of filtration?
Your answer : b. afferent arteriole, glomerular capillary, efferent arteriole
Correct answer: d. afferent arteriole, glomerular capillary, Bowman's capsule
3. Bowman's capsule is connected to the beginning of the
You correctly answered: b. proximal convoluted tubule.
4. The functional unit of the kidney is the
You correctly answered: c. nephron.
5. During the process of renal reabsorption, fluid and solutes move from the
You correctly answered: b. renal tubule into the peritubular capillaries.
02/03/17 page 1
Experiment Results
Predict Question:
Predict Question 1: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the
afferent arteriole?
Your answer : b. Both pressure and filtration rate will decrease.
Predict Question 2: What will happen to the glomerular capillary pressure and filtration rate if you increase the radius of the
afferent arteriole?
Your answer : a. Both pressure and filtration rate will increase.
Predict Question 3: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the
efferent arteriole?
Your answer : a. Both pressure and filtration rate will increase.
Stop & Think Questions:
Caffeine consumption leads to increased urine formation. From the results in this experiment thus far, you might propose
that
You correctly answered: d. caffeine dilates the afferent arteriole.
When you are in the desert and dehydrating, which of the following arteriole combinations would benefit you the most?
You did not answer this question.
Correct answer: c. afferent constriction and efferent dilation
Experiment Data:
Afferent Radius Efferent Radius Beaker Press. Glomerular Press. Glom. Filt. Rate Urine Volume
(mm) (mm) (mm Hg) (mm Hg) (ml/min) (ml)
0.50 0.45 90 55.08 124.99 200.44
0.45 0.45 90 51.54 81.06 179.88
0.40 0.45 90 48.52 43.66 143.91
0.35 0.45 90 46.16 14.35 76.33
0.55 0.45 90 58.94 172.86 212.87
0.60 0.45 90 62.88 221.69 220.74
0.50 0.45 90 55.08 124.99 200.44
0.50 0.40 90 56.10 137.69 227.49
0.50 0.35 90 56.84 146.82 247.96
0.50 0.30 90 57.34 152.96 262.23
02/03/17 page 2
Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
1. If you increase the afferent arteriole radius and keep all other variables constant, the glomerular filtration rate would
You correctly answered: a. increase.
2. If you decrease the efferent arteriole radius and keep all other variables constant, the volume of urine flowing into the
urinary bladder would
You correctly answered: a. increase.
3. If you increase the efferent arteriole radius and keep all other variables constant, the glomerular filtration rate would
You correctly answered: b. decrease.
4. If you decrease the afferent arteriole radius and keep all other variables constant, the volume of urine flowing into the
urinary bladder would __________.
You correctly answered: b. decrease.
02/03/17 page 3
Review Sheet Results
1. What are two primary functions of the kidney?
Your answer:
1. Menjaga keseimbangan (homeostasis) cairan dan elektrolit tubuh
2. Membuang produk sisa metabolisme dan substansi asing dari tubuh (which are potentially toxic if accumulate inside the
body)
2. What are the components of the renal corpuscle?
Your answer:
1. Glomerulus, plus its adjacent arterioles (afferent and efferent)
2. Bowmann's Capsule
3. Starting with the renal corpuscle, list the components of the renal tubule as they are encountered by filtrate.
Your answer:
1. Renal corpuscle (glomerulus, Bowmann's capsule)
2. Proximal contorted tubule
3. Loop of Henle
4. Distal controted tubule
5. Collecting duct
(and then the urine will enter the pelviocalyxes region of each kidney before entering the ureter)
4. Describe the effect of decreasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How
well did the results compare with your prediction?
Your answer:
Our prediction was correct.
Apabila diameter arteriola aferen menyempit (vasokonstriksi), maka volume darah yang masuk ke glomerulus tidak banyak,
sehingga tekanan di dalam glomerulus dan laju filtrasi darah (GFR; glomerular filtration rate) pun menurun.
5. Describe the effect of increasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How
well did the results compare with your prediction?
Your answer:
Our prediction was correct.
Apabila diameter arteriola aferen melebar (vasodilatasi), maka volume darah yang masuk ke glomerulus akan meningkat,
sehingga tekanan di dalam glomerulus dan laju filtrasi darah (GFR) pun ikut meningkat.
6. Describe the effect of decreasing the efferent arteriole radius on glomerular capillary pressure and filtration rate. How
well did the results compare with your prediction?
Your answer:
Our prediction was correct.
Apabila diameter arteriola eferen menyempit (vasokonstriksi), maka resistensi kapiler akan meningkat, sehingga tekanan di
dalam glomerulus dan laju filtrasi darah (GFR) pun meningkat.
7. Describe the effect of increasing the efferent radius on glomerular capillary pressure and filtration rate.
Your answer:
Apabila diameter arteriola eferen melebar (vasodilatasi), maka resistensi kapiler akan menurun, sehingga tekanan di dalam
02/03/17 page 4
glomerulus dan laju filtrasi darah (GFR) pun ikut menurun.
02/03/17 page 5
