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Nursing Guide: Ranitidine Use

Generic name: Ranitidine Brand name: Zantac Classification: Antiulcer drug Mechanism of action: Inhibits histamine at H2 receptor sites in gastric parietal cells, reducing gastric acid secretion. Has some antibacterial action against H. pylori. Indications: Treatment and prevention of heartburn, acid indigestion, and sour stomach. Prophylaxis of GI hemorrhage from stress ulceration. Adverse effects: Drowsiness, dizziness, constipation, black tarry stools, fever, sore throat, diarrhea, rash, confusion, hallucinations. May cause false-positive urine protein tests or gray/black st
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0% found this document useful (0 votes)
91 views3 pages

Nursing Guide: Ranitidine Use

Generic name: Ranitidine Brand name: Zantac Classification: Antiulcer drug Mechanism of action: Inhibits histamine at H2 receptor sites in gastric parietal cells, reducing gastric acid secretion. Has some antibacterial action against H. pylori. Indications: Treatment and prevention of heartburn, acid indigestion, and sour stomach. Prophylaxis of GI hemorrhage from stress ulceration. Adverse effects: Drowsiness, dizziness, constipation, black tarry stools, fever, sore throat, diarrhea, rash, confusion, hallucinations. May cause false-positive urine protein tests or gray/black st
Copyright
© © All Rights Reserved
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Drug Study

Generic name/
Brand name/
Classification

Route of
administration/
Dosage/
Frequency

Indication/Action

Generic: Ranitidine

Route: Oral

Mechanism of Action:

Brand: Zantac

Dosage: 50mg

Timing:OD
Classification: Antiulcer

Inhibits the action of histamine at


the H2 receptor site located
primarily in gastric parietal cells,
resulting in inhibition of gastric
acid secretion
has some antibacterial action
against H. pylori

Indication

Treatment and prevention of


heartburn, acid indigestion, and
sour stomach.

Prophylaxis of GI hemorrhage from


stress ulceration

Contraindication

Hypersensitivity, Cross-sensitivity
may occur; some oral liquids contain
alcohol and should be avoided in
patients with known intolerance

Adverse effect

Nursing
Responsibility

Instruct patient not


to take new
medication w/o
consulting
physician
Instruct patient to
take as directed
and do not
increase dose
Allow 1 hour
between any other
antacid and
ranitidine
Avoid excessive
alcohol
Assess patient for
epigastric or
abdominal pain
and frank or occult
blood in the stool,
emesis, or gastric
aspirate
Nurse should
know that it may
cause false-

positive results for


urine protein; test
with sulfosalicylic
acid
Inform patient that
it may cause
drowsiness or
dizziness
Inform patient that
increased fluid
and fiber intake
may minimize
constipation
Advise patient to
report onset of
black, tarry stools;
fever, sore throat;
diarrhea;
dizziness; rash;
confusion; or
hallucinations to
health car
professional
promptly
Inform patient that
medication may
temporarily cause
stools and tongue
to appear gray
black
Instruct
patients to
monitor for

and report
occurrence of
drug-induced
adverse
reaction

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