Drug Study
Generic name/
Brand name/
Classification
Route of
administration/
Dosage/
Frequency
Indication/Action
Generic: Ranitidine
Route: Oral
Mechanism of Action:
Brand: Zantac
Dosage: 50mg
Timing:OD
Classification: Antiulcer
Inhibits the action of histamine at
the H2 receptor site located
primarily in gastric parietal cells,
resulting in inhibition of gastric
acid secretion
has some antibacterial action
against H. pylori
Indication
Treatment and prevention of
heartburn, acid indigestion, and
sour stomach.
Prophylaxis of GI hemorrhage from
stress ulceration
Contraindication
Hypersensitivity, Cross-sensitivity
may occur; some oral liquids contain
alcohol and should be avoided in
patients with known intolerance
Adverse effect
Nursing
Responsibility
Instruct patient not
to take new
medication w/o
consulting
physician
Instruct patient to
take as directed
and do not
increase dose
Allow 1 hour
between any other
antacid and
ranitidine
Avoid excessive
alcohol
Assess patient for
epigastric or
abdominal pain
and frank or occult
blood in the stool,
emesis, or gastric
aspirate
Nurse should
know that it may
cause false-
positive results for
urine protein; test
with sulfosalicylic
acid
Inform patient that
it may cause
drowsiness or
dizziness
Inform patient that
increased fluid
and fiber intake
may minimize
constipation
Advise patient to
report onset of
black, tarry stools;
fever, sore throat;
diarrhea;
dizziness; rash;
confusion; or
hallucinations to
health car
professional
promptly
Inform patient that
medication may
temporarily cause
stools and tongue
to appear gray
black
Instruct
patients to
monitor for
and report
occurrence of
drug-induced
adverse
reaction