Human Physiology/The endocrine system
Endocrine
Gland
Hormone Released
Chemical Class Target Tissue/Organ
Major Function of Hormone
Hypothalamus
Hypothalamic releasing and
inhibiting hormones
Peptide
Anterior pituitary
Regulate anterior pituitary hormone
Posterior
Pituitary
Antidiuretic (ADH)
Peptide
Kidneys
Stimulates water reabsorption by kidneys
Oxytocin
Peptide
Uterus, mammary
glands
Stimulates uterine muscle contractions and
release of milk by mammary glands
Thyroid stimulating (TSH)
Glycoprotein
Thyroid
Stimulates thyroid
Adrenocorticotropic (ACTH)
Peptide
Adrenal cortex
Stimulates adrenal cortex
Gonadotropic (FSH, LH)
Glycoprotein
Gonads
Egg and sperm production, sex hormone
production
Prolactin (PRL)
Protein
Mammary glands
Milk production
Growth (GH)
Protein
Soft tissue, bones
Cell division, protein synthesis and bone growth
Thyroxine (T4) and
Triiodothyronie (T3)
Iodinated amino All tissue
acid
Increase metabolic rate, regulates growth and
development
Calcitonin
Peptide
Bones, kidneys and
intestine
Lowers blood calcium level
Parathyroids
Parathyroid (PTH)
Peptide
Bones, kidneys and
intestine
Raises blood calcium level
Adrenal Cortex
Glucocorticoids (cortisol)
Steroid
All tissue
Raise blood gluclose level, stimulates breakdown
of protein
Mineralocorticoids (aldosterone) Steroid
Kidneys
Reabsorb sodium and excrete potassium
Sex Hormones
Steroid
Gonads, skin, muscles
and bones
Stimulates reproductive organs and brings on sex
characteristics
Adrenal
Medulla
Epinephrine and norepinephrine
Modified amino
acid
Cardiac and other
muscles
Released in emergency situations, raises blood
glucose level, fight or flight response
Pancreas
Insulin
Protein
Liver, muscles,
adipose tissue
Lowers blood glucose levels, promotes formation
of glycogen
Glucagon
Protein
Liver, muscles,
adipose tissue
Raises blood glucose levels
Testes
Androgens (testosterone)
Steroid
Gonads, skin, muscles
and bone
Stimulates male sex characteristics
Ovaries
Estrogen and progesterone
Steroid
Gonads, skin, muscles
and bones
Stimulates female sex characteristics
Thymus
Thymosins
Peptide
T lymphocytes
Stimulates production and maturation of T
lymphocytes
Pineal Gland
Melatonin
Modified amino
acid
Brain
Controls circadian and circannual rhythms,
possibly involved in maturation of sexual organs
Anterior
Pituitary
Thyroid
Hormones can be chemically classified into four groups:
1. Amino acid-derived: Hormones that are modified amino acids.
2. Polypeptide and proteins: Hormones that are chains of amino acids of less than or more than about 100 amino
acids, respectively. Some protein hormones are actually glycoproteins, containing glucose or other carbohydrate
groups.