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Zolpidem: Uses, Dosage, and Effects

Zolpidem is a sedative used to treat insomnia. It works by binding to GABA receptors in the brain. It is rapidly absorbed orally and converted to inactive metabolites that are eliminated by the kidneys. Onset of action is within 15 minutes for an oral tablet and peak effect occurs within 2 hours. It is prescribed for short-term treatment of insomnia and contraindicated in those with sleep apnea or hypersensitivity. Common side effects include drowsiness and dizziness. Nurses monitor patients for drowsiness and mental status changes after administration.

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585 views1 page

Zolpidem: Uses, Dosage, and Effects

Zolpidem is a sedative used to treat insomnia. It works by binding to GABA receptors in the brain. It is rapidly absorbed orally and converted to inactive metabolites that are eliminated by the kidneys. Onset of action is within 15 minutes for an oral tablet and peak effect occurs within 2 hours. It is prescribed for short-term treatment of insomnia and contraindicated in those with sleep apnea or hypersensitivity. Common side effects include drowsiness and dizziness. Nurses monitor patients for drowsiness and mental status changes after administration.

Uploaded by

Arnzz Agbulos
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Drug Data Generic Name zolpidem Trade Name Ambien, Edluar, Zolpimist Patients Dose

Classification Therapeutic# sedati%e Pharmacologic

Mechanism of Action !roduces &'# depression by binding to (A)A receptors. *as no analgesic properties. Pharmaco,inetics A# +apidly absorbed ,ollo-ing oral administration. &ontrolled.release ,ormulation releases 10 mg immediately, t/en anot/er 2.5 mg later. D# 0inimal amounts enter breast mil12 remainder o, distribution not 1no-n. M-'# &on%erted to inacti%e metabolites, -/ic/ are e3creted by t/e 1idneys. Onset !"(E+, #pray ,#$4 rapid Pea, !"4 50 min 6 2 /r. !".E+4 2.7 /r !".spray, #$4 un1no-n Duration !"(E+ 46.8/r !".spray,#$4un1no-n Drug .alf "ife 2.565 /r.

Indication General Indications 9nsomnia Patients Actual Indication

Contraindications *ypersensiti%ity2 #leep apnea. Precaution *istory o, pre%ious psyc/iatric illness, suicide attempt, drug or alco/ol abuse2 *epatic impairment (initial dose reduction recommended 2 (eri4 (eriatric patients (initial dose decrease recommended 2 !ulmonary disease2 "), $actation!edi4 !regnancy, lactation, or c/ildren (sa,ety not establis/ed . .Drug interaction (drug to drug &'# depression may:-it/ sedatives/ h&pnotics, alcohol, phenothia0ines, tric&clic antidepressants, opioid analgesics, or antihistamines.

Pregnanc& Categor& C

Minimum Dose PO !"#5mg Ma$imum Dose PO%!"#12.5mg Contents zolpidem Availabilit& and color Tablets# 5 mg, 10 mg. '$tended(release tablets# 6.25 mg, 12.5 mg. !ublingual tablets )'dluar*# 5 mg, 10 mg. Oral spra& )+olpimist*# 5 mg/spray (60 sprays/container Routes of administration !", #$

Adverse Reaction CN!# daytime dro-siness, dizziness, abnormal t/in1ing, amnesia, be/a%ior c/anges, ;drugged< ,eeling, /allucinations, sleep.dri%ing. GI# diarr/ea, nausea, %omiting. Misc# A'A!*=$A&>9& +EA&>9"'#, /ypersensiti%ity reactions, p/ysical dependence, psyc/ological dependence, tolerance.

Nursing Responsibilities 1efore 1. Asses patient?s diagnosis. 2. Assess patient?s mental status. 5. Assess i, patient /ad any /istory o, substance abuse. 7. Assess patient?s sleep patterns2 5. Assess i, patient is e3periencing any pain. During 1. &on,irm patient?s identity. 2. !ro%ide com,ort measures and reduce e3ternal stimuli to increase e,,ecti%eness o, mediation. 5. >ablets cannot be crus/ed, brea1 or c/e-. 7. Assist t/e patient in ta1ing oral medication. 5. @o not ta1e oral spray ,orm -it/ or immediately a,ter a meal. After 1. Ensure t/at oral medication is properly s-allo-ed by t/e patient. 2. "bser%e proper documentation o, administered medication. 5. 9nstruct t/e patient to rest rig/t a,ter ta1ing t/is medication. 7. "bser%e patient?s be/a%ior closely ,or atleast 15.50 minutes a,ter administration. 5. 0onitor patient?s A/# t/roug/out t/e t/erapy.

!ource#

@eglin, B. et. Al. 200C. @a%is?s @rug (uide ,or 'urses. 12t/ ed. D.A. @a%is. pp 1515 .1515

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