NURS 1556 Clinical Medications Worksheets
Generic Trade Name Classification Dose Route Time/frequency
Name Antihypertensive
Lisinopril Prinivil, Zestril ACE inhibitors 10 mg PO QD
Peak Onset Duration For IV meds, compatibility with IV drips and /or solutions
6 hr 1 hr 24 hr N/A
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions- Hypersensitivity;
For Hypertension—blocks the conversion of in geriatric: initial dosage reduction due to age-related
angiotensin I to the vasoconstrictor angiotensin II, decline in renal function.
increases the plasma renin levels and reduces
aldosterone levels. Net result is systemic vasodilation, Common side effects: CNS: dizziness, drowsiness,
lowers the blood pressure. fatigue, H/A, insomnia, vertigo, weakness. Resp: cough,
dyspnea. CV: hypotension, chest pain, edema, tachycardia.
For CHF- management—excretion of sodium and Endo: hyperuricemia. GI: taste disturbances, abdominal
water, and retention of potassium. pain, anorexia, constipation, diarrhea, nausea, vomiting.
GU: proteinuria, renal dysfunction, renal failure. Derm:
flushing, pruritis, rashes. F and E: hyperkalemia. Hemat:
AGRANULOCYTOSIS. MS: back pain, muscle cramps,
myalgia. Misc: ANGIOEDEMA, fever.
Interactions with other patient drugs, OTC or Lab value alterations caused by medicine: serum K+,
herbal medicines (ask patient specifically) BUN, and creatinine may rise, Na+ may decrease. Monitor
CBC, may have slight decrease in Hgb and, Hct,
On Norvasc- risk for hypotension with concurrent use leucopenia, and eosinophilia. May increase AST, ALT, alk
phos., serum bilirubin, uric acid, and glucose.
Be sure to teach the patient the following about this
medication:
Take same time daily. Change positions slowly. May cause
dizziness. May cause taste impairment that generally
resolves in 8-10 weeks.
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Why would you hold or not give this Check after giving:
Vital signs before giving Rx. Monitor BP med? Decrease in BP without
and pulse frequently during initial dose BP < 100 systolic or HR < 60 appearance of excessive side
adjustment. Monitor weight and assess Signs of serious adverse effects e.g. effects. Decrease in CHF
lungs for rales/crackles, dyspnea. Assess for angioedema. symptoms.
peripheral edema, jugular venous distention Monitor Labs, especially for
potassium( normal range 3.5-
5)