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Methergine: Uses, Side Effects, and Precautions

Methylergonovine maleate (Methergine) is a semi-synthetic ergot alkaloid used to prevent and control postpartum hemorrhage. It is available as tablets containing 0.2 mg of methylergonovine maleate and in 1 mL sterile ampuls containing 0.2 mg for intramuscular or intravenous injection. Potential side effects include increased blood pressure, seizures, fainting, and chest pain. Patients should tell their doctor about any allergies or medical conditions like kidney disease or high blood pressure before taking this medication.

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Victor Conde
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192 views3 pages

Methergine: Uses, Side Effects, and Precautions

Methylergonovine maleate (Methergine) is a semi-synthetic ergot alkaloid used to prevent and control postpartum hemorrhage. It is available as tablets containing 0.2 mg of methylergonovine maleate and in 1 mL sterile ampuls containing 0.2 mg for intramuscular or intravenous injection. Potential side effects include increased blood pressure, seizures, fainting, and chest pain. Patients should tell their doctor about any allergies or medical conditions like kidney disease or high blood pressure before taking this medication.

Uploaded by

Victor Conde
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

ethergine (methylergonovine maleate) Tablets, USP (methylergonovine maleate) Injection, USP

DRUG DESCRIPTION Methergine (methylergonovine maleate) is a semi-synthetic ergot alkaloid used for the prevention and control of postpartum hemorrhage.

Methergine (methylergonovine maleate) is available in sterile ampuls of 1 mL, containing 0.2 mg methylergonovine maleate for intramuscular or intravenous injection and in tablets for oral ingestion containing 0.2 mg methylergonovine maleate.

Tablets

Active Ingredient: methylergonovine maleate, USP, 0.2 mg.

Inactive Ingredients: acacia, carnauba wax, D&C Red #7, FD&C Blue #1, gelatin special, lactose, maleic acid, mixed parabens, povidone, sodium benzoate, sodium hydroxide, starch, stearic acid, sucrose, talc, and titanium dioxide.

Ampuls, 1 mL, clear, colorless solution.

Active Ingredient: methylergonovine maleate, USP, 0.2 mg.

Inactive Ingredients: maleic acid, 0.10 mg; sodium chloride, 7.0 mg; water for injection, qs to 1 mL.

Chemically, methylergonovine maleate is designated as ergoline-8-carboxamide, 9,10-didehydro-N-[1(hydroxymethyl)propyl]-6-methyl-, *8(S)+-, (Z)-2-butenedioate (1:1) (salt).

Its structural formula is

What are the possible side effects of methylergonovine (Methergine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

increased blood pressure (severe headache, blurred vision); seizure (convulsions); feeling light-headed, fainting; pounding heartbeat; chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;... Read All Potential Side Effects and See Pictures of Methergine

What are the precautions when taking methylergonovine maleate (Methergine)?

Before taking methylergonovine, tell your doctor or pharmacist if you are allergic to it; or to similar ergot alkaloids (such as ergonovine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood pressure, heart disease (such as venoatrial shunts, mitral valve

stenosis), blood vessel disease (such as Raynaud's disease), complications during pregnancy (such as preeclampsia, eclampsia).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can...

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