DRUG NAME
ACTION
INDICATION
CONTRAINDICATION
ADVERSE EFFECT
NURSING RESPONSIBILITIES
Zantac Brand Name Ranitidine Generic
Inhibits the action of histamine at the H2 receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion.
Treatment and Hypersensitivity, prevention of heartburn, acid Cross-sensitivity may indigestion, and sour occur; some oral stomach. liquids contain alcohol and should be avoided in patients with known intolerance. Use Cautiously in: Renal impairment Geriatric patients (more susceptible to adverse CNS reactions) Pregnancy or Lactation
CNS: Confusion, dizziness, drowsiness, hallucinations, headache CV: Arrhythmias GI: Altered taste, black tongue, constipation, dark stools, diarrhea, drug-induced hepatitis, nausea GU: Decreased sperm count, impotence
Assess patient for epigastric or abdominal pain and frank or occult blood in the stool, emesis, or gastric aspirate. Inform patient that it may cause drowsiness or dizziness. Advise patient to report onset of black, tarry stools; fever, sore throat; diarrhea; dizziness; rash; confusion; or hallucinations to health car professional promptly.
Dosage 50mg IV q8
Classification Anti-ulcer agents
Route IV
DRUG NAME
ACTION
INDICATION
CONTRAINDICATION
ADVERSE EFFECT
NURSING RESPONSIBILITIES
Celebrex Brand Name Celecoxib Generic
Relief of signs and Decreased pain and symptoms of inflammation caused osteoarthritis. by arthiritis Relief of signs and Inhibits the enzyme symptoms of COX-2. This enzyme rheumatoid arthritis is required for the in adults. synthesis of prostaglandins
Dosage 200 mg PRN Classification Anti-rheumatics, NSAIDS
Route oral
Celecoxib is dizziness, contraindicated in drowsiness, patients with known headache hypersensitivity to ,insomnia celecoxib. ,fatigue Celecoxib should not be given to patients who have demonstrated CV: allergic-type reactions peripheraledema to sulfonamides. such patients . EENT: ophthalmic effects, tinnitus, pharyngitis, rhinitis, sinusitis GI: nausea, diarrhea, constipation,
Assess patients range of motion, degree of swelling, and pain in affected joints before and periodically throughout therapy. Assess patient for allergy to sulfonamides, aspirin, or NSAIDS. Patients with these allergies should not receive celecoxib.
DRUG NAME
ACTION
INDICATION
CONTRAINDICATION
ADVERSE EFFECT
NURSING RESPONSIBILITIES
Brand Name Cefuroxime Generic
Inhibits cell wall synthesis promoting osmotic instability usually bactericidal
Serious lower respiratory tract infections, UTIs, skin and skinstructure infections, bone and joint infections, septicemia, meningitis, and gonorrhea
Contraindicated in patients hypersensitive to drug or other cephalosporin. Use cautiously in patients hypersensitive to penicillin because of possibility of crosssensitivity with other beta lactam antibiotics
CV: phlebitis, thrombophlebitis GI: diarrhea, anorexia, vomiting Hematologic: hemolytic anemia, thrombocytopenia, transient neutropenia, eosinophilia
Before giving dug. ask patient if she is allegic to penicillin or cephalosporin. Obtain specimen for culture and sensitivity tests before giving first dose. absorption of oral drug is induced
Dosage Q8
Route IV
DRUG NAME
ACTION
INDICATION
CONTRAINDICATION
ADVERSE EFFECT
NURSING RESPONSIBILITIES
Amikin Brand Name Amikacin Sulfate Generic
Inhibit protein synthesis in bacterial cell
Dosage
Short-term treatment Toxic reaction with an Nephrotoxicity (eg, of serious susceptible aminoglycoside azotemia, oliguria), infections, including antibiotic ototoxicity, septicemia, neurotoxicity, respiratory tract, neuromuscular bones and joints blockade (eg, muscular paralysis, apnea); rare: rash, drug fever, headache, tremor, GI upset, paresthesia, eosinophilia, arthralgia, anemia, hypotension, hypomagnesium
Discontinue or adjust dose if auditory, vestibular, or renal dysfunction develops; monitor serum levels periodically. Monitor BUN, CrCl, serum creatinine levels before, frequently during, and after therapy. Perform audiogram in high-risk patients. Maintain hydration. adequate
Route IV/IM
Classification Aminoglycoside
