DRUG ACTION INDICATION CONTRAINDICATION DRUG TO DRUG ADVERSE NURSING

INTERACTION REACTION CONSIDERATION

Generic Unclear. May alter Psychotic disorders. Hypersensitivity to Activated charcoal, CNS: extra As appropriate,
Fluphenazine psychiatric drug, sulfite (with adsorbent pyramidal review all other
decanoate mesolimbic injectable form) or antidiarrheals and reactions, significant and life-
dopamine receptors benzoyl alcohol. antacids: decrease drowsiness threatening adverse
in brain and reduce fluphenazine reactions.
release of Angle closure absorption.
hypothalamic and glaucoma.
hypophyseal Anticholinergics:
hormones thought Bone marrow decreased
to depress reticular depression. fluphenazine
Brand activating system, effects.
Modecate thereby preventing Severe hepatic or
psychotic cardiovascular Antidepressants,
symptoms. disease. antihistamines,
general anesthetics,
MAO inhibitors:
additive CNS
depression.

Antihypertensive:
Classification additive
Anxiolytic, hypotension
antipsychotic
Barbiturates:
increased
fluphenazine
metabolism and
decreased efficacy.
 DRUG ACTION INDICATION CONTRAINDICATION DRUG TO DRUG ADVERSE NURSING
INTERACTION REACTION CONSIDERATION
Generic Unknown. Thought Symptomatic Hypersensitivity to Antihypertensives, CNS: confusion, As appropriate,
Haloperidol to block treatment of drug, tartrazine, nitrates: additive drowsiness, review all other
postsynaptic psychotic disorders sesame oil or hypotension. restlessness, significant and life-
dopamine receptors or Tourette benzoyl alcohol. extrapyramidal threatening adverse
in brain and syndrome. CNS depressants: reactions. reactions.
increase dopamine Severe CNS additive CNS
turnover rate, Schizophrenia in depression or depression. EENT: blurred
inhibiting signs and patients who need comatose states. vision.
symptoms of prolonged Epinephrine: severe
Brand psychosis. parenteral Parkinson’s disease. hypotension and
Apo- Haloperidol antipsychotic tachycardia.
therapy.
Methyldopa:
dementia.

Classification
Antipsychotic
 DRUG ACTION INDICATION CONTRAINDICATION DRUG TO DRUG ADVERSE NURSING
INTERACTION REACTION CONSIDERATION
Generic Relieves nausea, Acute schizophrenia Hypersensitivity to Anabolic steroids, CNS: paresthesia, As appropriate,
Chlorpromazine vomiting, hiccups or mania. drug, sulfite (with chloramphenicol, dizziness, vertigo, review all other
and signs and injectable form) or MAO inhibitors, malaise, headache. significant and life-
symptoms of benzoyl alcohol. salicylates, threatening adverse
psychosis. sulfonamides: CV: increased risk of reactions.
Angle closure increased CV mortality.
glaucoma. hypoglycemia
EENT: tinnitus.
Bone marrow Beta- adrenergic
Brand depression. blockers: prolonged GI: nausea,
Thorazine hypoglycemia heartburn,
Severe hepatic or epigastric distress.
cardiovascular Oral anticoagulants:
disease. increased GU: tea-colored
hypoglycemic urine.
activities.
SKIN: rash, pruritus,
erythema.

Classification
Antipsychotic