PATHOPHYSIOLOGY
Middle age (female > male before age 50),
obesity, infection, pregnancy, hormonal
contraceptive, celiac disease. Cirrhosis,
pancreatitis, diabetes mellitus
Cholelithiasis
Refers to the formation of calculi
(e.g. gallstones in the gallbladder)
Major constituents are cholesterol and
pigment
Cholecystectomy Gallstone in bile Pain Fever Nausea and Jaundice
duct vomiting
Removal of the There is inflammation Increase
gallbladder after Bile stasis due to infection Gastric irritation bilirubin
ligation of the
cystic duct
Bile accumulates Bacterial Abnormal fat
Body will return to in the liver proliferation digestion There is restlessness
normal function and Increase in RR,
temp, PR and WBC
values
Gallbladder and Diarrhea
Recovery Cholestatic duct infection
Biliary
cirrhosis Rupture of Cholecystitis If not treated
gallbladder if
Peritonitis Death