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AGE Pathophysiology

This document outlines the pathophysiology of gastrointestinal infections. It shows that gastrointestinal infections can be caused by both non-modifiable factors like age and modifiable environmental factors like food handling. The microorganisms attach to the small intestine and enter mature cells, causing pain by stimulating chemoreceptors. This leads to structural changes and inflammation in the small intestine bowel that allow bacteria to enter the bloodstream, increase white blood cells, and release endotoxins and pyrogens that cause fever, diarrhea by inhibiting sodium and water reabsorption, and increasing fluid secretion.

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josephcanlas
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5K views2 pages

AGE Pathophysiology

This document outlines the pathophysiology of gastrointestinal infections. It shows that gastrointestinal infections can be caused by both non-modifiable factors like age and modifiable environmental factors like food handling. The microorganisms attach to the small intestine and enter mature cells, causing pain by stimulating chemoreceptors. This leads to structural changes and inflammation in the small intestine bowel that allow bacteria to enter the bloodstream, increase white blood cells, and release endotoxins and pyrogens that cause fever, diarrhea by inhibiting sodium and water reabsorption, and increasing fluid secretion.

Uploaded by

josephcanlas
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

Pathophysiology (Client Centered)

Non- Modifiable Modifiable


Age (children) Environment
Food Handling

Increase motility Microorganisms attach and enter mature enterocytes serotonin release
of intestines at the tips of small intestinal villi

stimulates
chemoreceptor
PAIN Structural changes to the small bowel mucosa and trigger zone
inflammation of the lamina propria

BACTEREMIA Bacteria invades blood stream across lamina propria INCREASE WBC

Bacteria releases endotoxin Releases pyrogens that stimulates hypothalamus

Increase amount of diarrheal Fluid FEVER

Active Secretion of Chloride Inhibition of Na & water reabsorption


& Bicarbonate Ions

DIARRHEA

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