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Drug Analysis: CNS: Headache

Piperacillin / Tazobactam, also known by the brand name Zosyn, is an intravenous antibiotic used to treat moderate to severe appendicitis, skin and soft tissue infections, and pneumonia caused by beta-lactamase-producing bacteria. Common side effects include headaches, diarrhea, nausea, vomiting, and rashes. When administering the drug, nurses should monitor for allergic reactions, obtain culture samples prior to the first dose, and watch for signs of hemorrhage or coagulation abnormalities due to high dosages.

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Ferdinand Sherwin Morata
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59 views1 page

Drug Analysis: CNS: Headache

Piperacillin / Tazobactam, also known by the brand name Zosyn, is an intravenous antibiotic used to treat moderate to severe appendicitis, skin and soft tissue infections, and pneumonia caused by beta-lactamase-producing bacteria. Common side effects include headaches, diarrhea, nausea, vomiting, and rashes. When administering the drug, nurses should monitor for allergic reactions, obtain culture samples prior to the first dose, and watch for signs of hemorrhage or coagulation abnormalities due to high dosages.

Uploaded by

Ferdinand Sherwin Morata
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

DRUG ANALYSIS

Name of Drug Piperacillin / Tazobactam

Generic Name Zosyn

Dosage

Indication

Drug Interaction

Adverse Effect CNS: headache, insomnia, fever

Nursing Responsibility

280 mg IVTT Treatment of every 12hr moderate to severe appendicitis, uncomplicated and complicated skin and skin structure infections, nosocomial or communityacquired pneumonia caused piperacillinresistant, piperacillin/tazob actam susceptible, beta-lactamaseproducing bacteria

Hypersensitivity to penicillins, cephalosphorins, or other drugs. Safety in children < 12 years old, pregnancy, lactation.

- Obtain history of hypersensitivity to penicillins, cephalosphorins, or other drugs prior to administration, GI: diarrhea, - Obtain specimen for culture and nausea, sensitivity prior to first dose of the constipation, drug; start drug pending results. vomiting, Periodic CBC with differential, platelet pseudomembrano count, Hgb & Hgt, and serum us colitis electrolytes. - Monitor for hypersensitivity response; SKIN: discontinue drug and notify physician hypersensitivity if allergic response noted. reactions ,rash, - Monitor for hemorrhagic pruritus manifestations because high dose may induce coagulation abnormalities. - Instruct family/significant others to report significant, unexplained diarrhea. - Monitor vital signs because of cardiac arrhythmias, hypertension and fever as adverse reactions. - Instruct the mother not to breast feed the baby while taking the drug without consulting physician.

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