An official website of the United States government
The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
National Institute of Environmental Health Sciences
Use this QR code to view the newest version of this document
BMDExpress is a desktop application for Windows, Mac or Linux that enables analysis of dose-response data produced in differential gene expression experiments. It provides stepwise workflows that combine benchmark dose (BMD) calculations with functional classification analysis.
ChemBioTox (CBT) is a relational database comprising calculated and measured toxicological data for over 1 million chemicals and their metabolites. These data can be leveraged to identify untested chemicals and perform read across to predict these chemicals' attributes.
ChemMaps.com v2.0 is an open-access web-based tool designed to simplify navigation of chemical space. It can be used for read-across analysis, risk assessment, and the exploration of unknown chemicals.
DNT-DIVER is a web-based data analysis, integration, and visualization tool designed to serve as a central repository for hosting DNT data for the DTT and its stakeholders.
The DASS App is an open-source web application to predict skin sensitization using defined approaches. It enables users to apply validated non-animal approaches to their own data.
An open-source, object-oriented R software package for characterizing the risk of perturbing molecular targets involved in adverse human health outcomes based on exposure to spatially-referenced stressor mixtures.
ICE is an open-access, user-friendly platform developed by NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). ICE provides curated toxicologically relevant data and interactive computational tools to support development and evaluation of new testing approaches.
MoVIZ is a cheminformatics pipeline developed using the free and open-source KNIME analytics platform and aims to democratize computational methods through intuitive, well-documented, and user-friendly graphical interfaces. Among MoVIZ tools is a workflow facilitating chemical grouping based on supervised and unsupervised machine learning approaches.
OPERA is a free and open-source/open-data suite of QSAR models that provides predictions for physicochemical properties, environmental fate parameters, ADME and toxicity endpoints to support non-animal approaches for predicting toxicity.
The package provides an R interface for processing concentration-response datasets using Curvep, a response noise filtering algorithm. Other parametric fitting approaches are also available.
R package for the Toxicological Prioritization Index (ToxPi): A statistical modeling framework that allows transparent integration and visualization of data across disparate sources (i.e. multimodal or multiscale information).
