Dupixent is a brand-name injection that doctors prescribe to treat certain conditions, including atopic dermatitis and asthma. Injection site reactions, such as pain, are common side effects of the medication.

The Food and Drug Administration (FDA) approved Dupixent to treat certain conditions in adults and some children. Those conditions include moderate to severe atopic dermatitis (a type of eczema) and certain forms of moderate to severe asthma. For more information about all the drug’s uses, check out this in-depth Dupxient article.

Dupixent comes as a single-dose prefilled syringe and pen. You can inject Dupixent as a subcutaneous injection (injection under your skin).

Injection site reactions, such as pain, are common side effects of Dupixent. Learn more about those side effects and best practices to help manage pain from Dupixent.

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In Dupixent’s studies, people often reported injection site reactions as side effects. These reactions may include the following:

  • redness or discoloration
  • itchiness
  • pain
  • inflammation and swelling

All of these reactions may happen at the Dupixent injection site. These side effects are typically mild and temporary. In some cases, they may go away on their own within a few hours.

Follow the instructions your doctor or pharmacist provides on how to inject Dupixent.

You can inject Dupixent into your thigh or abdomen outside of 2 inches from your belly button. If a caregiver gives you the injection, they can also inject it in the outer area of your upper arm. Other instructions for injecting Dupixent are to do the following:

  • Avoid injections on damaged, bruised, tender, or scarred skin.
  • Rotate injection sites.
  • Do not rub your skin after the injection.

Dupixent is available as a subcutaneous injection, which means you can inject it under your skin. Manufacturers didn’t design the drug for you to inject it into your muscle.

The drug’s manufacturer site provides support for injections, including best practices, training videos, and step-by-step instructions.

Treatment options

If you experience pain or other injection site reactions that don’t go away or are bothersome, talk with your doctor or pharmacist. They can recommend ways to help manage these side effects, which may include over-the-counter pain medications, such as ibuprofen (Advil, Motrin) or acetaminophen (Tylenol), or applying a cold compress to the area.

Dupixent is a prescription medication that doctors prescribe for certain conditions, including asthma and eczema. It’s available as a subcutaneous injection.

Injection site reactions, including pain, are common side effects of Dupixent. Using best practices while injecting Dupixent may help reduce the risk of these side effects.

Talk with your doctor or pharmacist if you have questions about how to inject Dupixent or experience bothersome side effects from the medication.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.