Past Grantees

Funding high-impact, high-quality basic, and translational research is essential for the identification and testing of new drugs and other therapies that could change how we treat hydrocephalus.

Our Past Grantees

That is why, each year, the Hydrocephalus Association runs grant cycles to fund individual researchers conducting innovative and exciting research that will improve our understanding of the condition, identify and test new interventions, and move new discoveries towards clinical use.

Accelerator Award

About the Award

In 2024, HA launched the Accelerator Award to fund the advancement of ongoing research at any stage from the bench-to-bedside. This grant provides support for established investigators for research focused on preventing hydrocephalus or developing non-invasive treatments.

A Large Animal Model of Germinal Matrix Hemorrhage for the Advancement of Choroid Plexus Therapies

This award was supported by Team Hydro.

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Innovator Award

About the Award

In 2015, HA launched the first-ever Innovator Award for Investigators in Hydrocephalus Research. The goal of this grant is to provide seed funding for bold and innovative research with the potential to transform the field of hydrocephalus.

Complement Alternative Pathway Initiation Contributes to Post-Hemorrhagic Hydrocephalus in a Neonatal GMH Model

This award was supported by Team Hydro.

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Utilizing Neurosurgical Specimens to Study Intraventricular Hemorrhage and the Feasibility of Targeted Gene Therapy

This award was supported by Team Hydro.

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Leveraging a Cortical Spheroid System to Understand the Pathogenesis of Hydrocephalus

This award was funded by the Rudi Schulte Research Institute.

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Improving neonatal hydrocephalus diagnosis, treatment, and prevention through metagenomics and genetic characterization in Ugandan cohorts.

This award was funded by the Rudi Schulte Research Institute.

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Determine the most effective treatment window and dose for a previously determined therapeutic target of Post-Hemmorhagic Hydrocephalus.

This award was supported by Team Hydro.

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Understand how the secretion and barrier functions of the choroid plexus are altered in response to inflammation. Develop shunt catheters with topographical changes to reduce shunt obstructions. Develop a patient-specific computational model and test ventricular catheters, placement, and outcomes with it to improve predictive capabilities of ventricular failure.

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Identify novel genes and pathways implicated in Post-Hemorrhagic Hydrocephalus (PHH) and identify potential biomarkers of PHH as well as explore potential drugs already developed which can be repurposed to target PHH.

This award was supported by Team Hydro.

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Utility of 3D gait analysis in reference to clinical assessments to detect significant change after a CSF taptest in patients investigated for iNPH

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2020 Innovator Award Recipient TITLE:  Professor, UC Department of Surgery INSTITUTION:  University of Cincinnati GOAL:  Dr.…

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2020 Innovator Award Recipient TITLE: Professor, Neurological Surgery INSTITUTION: University of Michigan GOAL:  Dr. Pandey…

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Assistant Professor, University of Kentucky

This project will determine if antioxidant therapy can reduce brain injury after intraventricular hemorrhage and post-hemorrhagic hydrocephalus (IVH/PHH). IVH/PHH occurs in preterm infants, and leads to oxidative stress and brain injury.

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2019 Innovator Award Recipient TITLE: Assistant Professor, Yale University GOAL: Understanding the role of cilia…

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2017 Innovator Award Recipient TITLE:  Assistant Professor, University of Washington GOAL:  Identify markers for infants…

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2017 Innovator Award Recipient TITLE:  Research Associate, Loma Linda University GOAL:  Understand how Germinal Matrix…

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Engineering in Hydrocephalus Prize

About the Award

The Engineering in Hydrocephalus Prize was created to award undergraduate or graduate research projects focused on engineering solutions for hydrocephalus. This award aims to encourage the next generation of scientists to think creatively and design projects that address the challenges of hydrocephalus. Awardees also receive mentorship opportunities by experts in the fields of bioengineering and hydrocephalus. With this award, we strive to increase diverse perspectives within our research ecosystem.

Yuli Wang developed an advanced artificial intelligence (AI)-based deep learning model to improve the accuracy of idiopathic normal pressure hydrocephalus (iNPH) diagnosis using medical imaging and clinical data.

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Haritosh Patel and Amy Huang have developed a new design for ventricular catheters (VCs) to address the high failure rates in hydrocephalus treatment, where current VCs often get blocked or infected.

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Bianka Valecruz developed a physical system to mimic the dynamic pressure, flow, and conditions within the brain. This provides a platform to analyze intracranial pressure and CSF flow in real-time in a controlled environment.

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Neuropsychology & Cognition Award

About the Award

The Neuropsychology and Cognition Award was created to advance research on quality of life aspects of hydrocephalus across the lifespan. The goal of this award is to support innovative research that broadly addresses the utility and development of neuropsychological and cognitive assessment tools.


Epidemiology Challenge Award

About the Award

The Epidemiology Challenge Award was created with the goal of developing reliable data on the epidemiology and economic impact of adult non-normal pressure hydrocephalus.

Albert Isaacs

Comprehensive Epidemiological and Economic Assessment of Non-Normal Pressure Adult Hydrocephalus (NNPAH) in the United States

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Next Generation Scientists Travel Award

[Formerly named the Young Investigator Travel Award]

 

About the Award

The National Conference on Hydrocephalus (HA CONNECT) brings together renowned clinicians and scientists with the hydrocephalus patient community. The Conference is an ideal place for young investigators to meet the patients and families affected by hydrocephalus and hopefully strengthen their commitment to a career focused on hydrocephalus. However, few scientists or medical professionals in training are able to attend. This award aims to encourage the next generation of hydrocephalus researchers to attend and allows them the opportunity to present their research.

Long Term Benefits with a Novel Drug Treatment in a Rat Model of Post-Hemorrhagic Hydrocephalus of Prematurity

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A. Scott Emmert, BS

(Gene) Talking About Hydrocephalus: Development of a New Rat Model of Neonatal Hydrocephalus

Jeffrey Horbatiuk

Re-imaging the FLO of the ventricle

Eri Iwasawa, MD, PhD

Inflammation and Impaired Neural Differentiation in CCDC39 Rat Model of Neonatal Hydrocephalus

Jason Karimy, MS

A role for inflammation: TLR-4-mediated cerebrospinal fluid hypersecretion in post-hemorrhagic and post-infectious hydrocephalus

Riccardo Serra, MD

Evaluating the effects of CSF proteins on valves and anti-siphoning devices in a benchtop shunt system

Margaret Tish, BS

Neuronal characterization of hydrocephalic symptoms

Joseph "Tyler" Vasas, BSEE

Glial Scar Formation And Concomitant Glymphatic Impairment In The Hydrocephalic Brain

Vanessa Wall, MA, MS

Social-emotional outcomes in children with hydrocephalus

Kathryn Woods, MS

Microglial Secreted IL-10 Mediates Increase in Neuron Death following S. epidermidis Biofilm Exposure

Kathrin Zimmerman, BA

Depression, Anxiety, Fatigue and Resilience in Children with Hydrocephalus

2018 Young Investigator Travel Award An Early Diagnostic Tool for Hydrocephalus in Premature Newborns

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2018 Young Investigator Travel Award MRI Features of High Volume Lumbar Puncture (HVLP): Responders Compared…

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2018 Young Investigator Travel Award Anti-Siphon Devices decease the rate of proximal shunt obstruction surgery

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2018 Young Investigator Travel Award Quantification and Differentiation of Periventricular White Matter (PVWM) Injury in…

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Cynthia Solomon Resident's Prize in Hydrocephalus

About the Award

One way the Hydrocephalus Association promotes research and leadership in hydrocephalus is through our annual Resident’s Prize. This prize is awarded each year to the most promising hydrocephalus-related research paper presented by a neurosurgical resident at the Pediatric Section meeting of the American Association of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS). The prize is designed to encourage young doctors to focus their research efforts on advancing treatment and care of individuals with hydrocephalus.

Cynthia Solomon, a co-founder and enduring advocate of HA, conceived the concept of the Resident’s Prize in 1998 to motivate neurosurgical residents to actively participate in research endeavors. To pay tribute to Cynthia's profound influence, this award underwent a renaming during our 40th anniversary celebrations in 2023. It will now be officially known as The Cynthia Solomon Resident’s Prize in Hydrocephalus, encapsulating her lasting legacy and dedication to advancing hydrocephalus research.

2024: Lauren Schulz, MD
Proteomic Insights into Blood-CSF Barrier Disruption and WBC Migration in Post-Infectious and Post-Hemorrhagic Hydrocephalus

2023: Peter Chiarelli, MD, DPhil
Quantitative Non-Invasive Measurement of Cerebrospinal Fluid Flow in Shunted Hydrocephalus

2022: Leonard Verhey, MD, PhD
Re-evaluation of ETV Success Score in Children with Hydrocephalus: Multicentered cohort study of Clinical Research Network.

2021: Michael M. McDowell, MD

 

2020: Mohammed Alshareef, MD
Complement Activation Leads to Worse Cognitive Outcomes Following Germinal Matrix Hemorrhage in a Chronic Mouse Model.

2019: Cameron Sadegh, MD
Intraventricular Hemorrhage Induces Rapid Intracellular Signaling in the Choroid Plexus and Chronic Changes in CSF Reabsorption.

2018: Elizabeth Kuhn, MD
Cross-sectional evaluation of transition readiness in the interdisciplinary spina bifida clinic

2017: Shawn Vuong, MD
CRISPR/Cas9-Based Development of progressive hydrocephaly (prh) Rat Model of Hydrocephalus

2016: Jonathan Jay Stone, MD
Treatment of Hydrocephalus in an Ovine Model with an Intraparenchymal Stent Prototype

2015: Brian Hanak, MD
Toward a better understanding of the cellular basis for cerebrospinal fluid shunt obstruction: report on the construction of a bank of explanted hydrocephalus devices

2014: Jason Blatt, MD
Incidence of Delayed Hydrocephalus Following In-Utero Myelomeningocele Repair

2013: Jennifer Strahle, MD
Early Treatment of Neonatal Intraventricular Hemorrhage-Associated Hydrocephalus with Systemic Deferoxamine

2012: Jayant P. Menon, MD
Significant Shunt Obstruction Caused by Parenchymal Tissue Shearing During Ventricular Catheter Implantation

2011: Ashley Tian, MD
Bilateral High-Grade Intraventricular Hemorrhage is Associated with Male Sex, Younger Gestational Age and Lower Birth Weight, But Not Other Perinatal Factors

2010: Ramin Eskandari, MD
Effects of Early and Late Reservoir Treatment in Experimental Neonatal Hydrocephalus

2009: Christopher Janson, MD
Immortalization and Functional Characterization of Rat Arachnoid Cells

2008: Ellen Air, MD
A longitudinal comparison of pre- and postoperative DTI parameters in young hydrocephalic children

2006: Kurtis Auguste, MD
Greatly Impaired Migration of Aquaporin 4 Deficient Astrogial Cells after Implantation into a Mouse Brain

2005: Jeffrey Greenfield, MD
Intraoperative Assessment of Third Ventriculostomy Success

2004: Jeff Pugh, MD
Can the skull Diploic space be utilized for Absorption of Cerebrospinal Fluid?
& Jay Riva-Cambrin, MD
Pediatric Posterior Fossa Tumors

2003: Martin Schumann, MD
Serum and CSF C-Reactive Protein in Shunt Infection Management

2002: Joshua Medow, MD
Quick Brain MRI verses CT scan for evaluating Shunted Hydrocephalus

2002: Jonathon Miller, MD
Aberrant Neuronal Development in Hydrocephalus

2001: Jake Timothy, MD
Treatment of Hydrocephalus Using a Choroid Plexus Specific Immunotoxin: an in vitro Study

1999: Kimberly Bingaman, MD
Hydrocephalus Induces the Proliferation of Cells in the Subventricular Zone

1998: Daniel Lieberman, MD
In Vitro Detection of fluid Flow in Ventriculoperitonal Shunts Using contrast Enhanced Ultrasound

1996: Martha Johnson, PhD.
Dr. Johnson studied the effects of hydrocephalus on animals, primarily canine, to determine the extent of brain damage inflicted when fluid exerts pressure on the brain.

1995: Richard Fox, MD
Cerebrospinal Fluid Absorptive Site of the Parasagittal Dura

1994: Monica Wehby-Grant, MD
The rabbit Model for Infantile Hydrocephalus: Regional Differences in the Cortical Metabolic Response to Hydrocephalus and to shunting

1993: Charles Bondurant, MD
The Epidemiology of Cerebrospinal Fluid Shunting

1992: Marcia DaSilva, MD
Reversal of High Energy Phosphate Metabolism changes in Experimental Hydrocephalus after CSF Shunting

1991: Nesher Asner, MD
Venous sinus Occlusion and Ventriculomegaly in Craniectomized Rabbits

1990: S.D. Michowiz, MD
High energy Phosphate Metabolism in Neonatal Hydrocephalus

1989: Eric Altschuler, MD
Management of Persistent Ventriculomegaly due to Altered Brain Compliance

Discovery Science Awards

About the Award

Discovery Science Awards provide multiyear support for high quality, innovative, and timely research projects by established investigators. The goals of this grant are to expand the scope of promising research studies, increase a lab’s focus on hydrocephalus, and involve junior investigators in conducting the research through a substantial multiyear commitment. In 2018, the Discovery Science Awards were focused on posthemorrhagic and postinfectious hydrocephalus research.

Dr. R. Reid Townsend is the Director of the Proteomics Core Laboratory and Professor of Medicine in the Division of Endocrinology at Washington University School of Medicine.

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Dr. Wagshul is an Associate Professor in the department of radiology at Albert Einstein College of Medicine.

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2013 Discovery Science Award Recipient 2013 Established Investigator TITLE: Director of Pediatric Neurosurgery, Hackensack University…

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2011 Discovery Science Award Recipient 2011 Established Investigator TITLE: Professor Emeritus of Laboratory Medicine and…

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Mentored Young Investigator Award

About the Award

The MYI Award program was run in 2009 and 2010 with the dual purpose of funding promising research relevant to hydrocephalus while fostering the development of young researchers.  The award helps ensure that qualified young scientists enter the field of hydrocephalus research and receive research training and experience under the guidance of highly trained, well-respected researchers who have demonstrated success in their field.

Dr. Riva-Cambrin is an associate professor and pediatric neurosurgeon at the University of Utah and Primary Children’s Hospital. Since the MYI award, Dr. Riva-Cambrin has received tenure and is Director of the Pediatric Neurosurgery Fellowship Program at the University of Utah School of Medicine.

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2010 Mentored Young Investigator Award Recipient Kate Finlayson Memorial Research Grant TITLE: Post-Doctoral Fellow, University…

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Joon W. (Simon) Shim

2009 Mentored Young Investigator Award Recipient TITLE: Visiting Faculty, Indiana University-Purdue University Indianapolis STUDY TITLE:…

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During the time of her grant, Dr. Moore was a Postdoctoral Fellow in neuropsychology at Weill Cornell Medical College. She received a B.A. in psychology from State University of New York at Geneseo, a M.A. and Ph.D. in clinical psychology from Suffolk University.

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