Applications
ORGANOID RESEARCH
Biology in Motion: Comprehensive Solutions for Organoid Research
Generate deeper, more translational insight from organoid models by capturing function, maturation, and disease-relevant mechanisms.
Harvard Bioscience supports organoid research across drug discovery, disease modeling, and precision medicine by enabling reliable electrophysiological readouts. Our diverse portfolio also assists your research at key stages of the organoid workflow, from genetic engineering and maintenance to live-cell imaging. By combining high-throughput measurements with controlled environments and advanced analysis, we help you generate predictive, reproducible data at the speed and rigor your research demands.
Study biology as it lives and changes.
OUR SOLUTIONS FOR ORGANOID RESEARCH
Mesh MEA
Scaffold MEA for long-term electrophysiology, preserving 3D organoid structure and accessing inner-layer signals
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Incub8™
Incubator-ready high-throughput multiwell MEA that supports truly simultaneous electrophysiology and imaging
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IntraCell
Multiparametric, long-term recordings integrating electrophysiology, contraction, and imaging from the same organoids
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3D MEA
Depth-resolved recording and stimulation in organoids with 3D electrodes, capturing inner cell-layer electrophysiology short-term
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Other MEAs
Versatile MEAs – planar, CMOS, or flexible – delivering precise recordings in organoids
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Patch Clamp
Gold-standard electrophysiology linking MEA electrical activity to underlying molecular mechanisms
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Live-Cell Imaging
Advanced imaging chambers for functional and structural studies in organoids
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Organoid Maintenance
High-precision fluidics and temperature control to maintain long-term organoid viability
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Genetic Engineering
Electroporation enabling deep genetic delivery for patient-specific organoid models
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Our organoid research platforms are featured in peer-reviewed studies across leading academic, pharma, and industry labs. Explore a selection of publications highlighting real-world applications and validated results.
The Right tool for Every Application
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| Planar & CMOS MEAs | 3D MEAs | Mesh MEAs | IntraCell | Incub8™ | |
| Primary Applications | Basic Research | Basic Research | Drug Discovery, Basic Research | Drug Safety, Basic Research | Drug Discovery, Drug Safety, Basic Research |
| Study Type | Short-term Studies | Short-term Studies | Short- & Long-term Studies | Short- & Long-term Studies | Short-term Studies |
| Throughput | Low & Medium Throughput | Low Throughput | Low Throughput | Medium Throughput | High Throughput |
| Resolution | Ultra-high & High Spatial Resolution | High Spatial Resolution | High Spatial Resolution | High Spatial Resolution | Multi-cellular Spatial Resolution |
| Recording Type | Surface Recordings | Inside Organoids Recordings | Inside Organoids Recordings | Surface & Inside Organoids Recordings | Surface Recordings |
| Imaging Capabilities | Live-cell Imaging* | Live-cell Imaging | Live-cell Imaging | Simultaneous Live-cell Imaging & Electrophysiology | Simultaneous Live-cell Imaging & Electrophysiology |
| Multiparametric Measurements | Only MEA | Only MEA | Only MEA | MEA, Action Potentials, Contraction, & Live-cell Imaging | MEA & Live-cell Imaging |
| Organoid Maintenance | Perfusion | Perfusion | Perfusion | Perfusion | Liquid Handling Compatibility |
* CMOS MEAs are not imaging-compatible due to their high electrode density.
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