PROVED
This has been solved in the affirmative.
Let $A\subseteq \mathbb{N}$ be an infinite set such that $\lvert A\cap \{1,\ldots,N\}\rvert=o(N)$. Is it true that\[\limsup_{N\to \infty}\frac{\lvert (A-A)\cap \{1,\ldots,N\}\rvert}{\lvert A\cap \{1,\ldots,N\}\rvert}=\infty?\]
The answer is yes, proved by Ruzsa
[Ru78].
See also
[245] for the sum set analogue.
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