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The difference is a bracket is more like adding in extra information , a dash however is more like a comma in a complex sentence/clause .
(2, 1) or (2, 4).
If a comma is needed, it normally comes after parenthesis.
You can use a comma after an opener , so if it is 'Finally' the opener you are talking about, then yes.
NO!!! The comma comes before 'although'. She said, 'I am tired", although he said "I am not tired".