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2009, International Journal of Environmental Research and Public Health
To assess the risk of lead poisoning among preschool and school-aged children in Bangladesh, 345 children were screened for blood lead levels (BLLs) from one rural and two urban areas in Bangladesh from September 2007 through January 2008. An urban industrial area at Tongi was identified as a disaster area, where 99% (104/105) of those tested had BLLs ≥10 µg/dL. Industrial emissions and use of leaded gasoline by two-stroke engine vehicles were identified as possible sources of lead in that area. A rural nonindustrial area at Chirirbandar, Dinajpur was identified as another high-risk area, where 14% of the children screened had BLLs ≥10 µg/dL. BLLs at the urban industrial area were significantly higher than those at the rural and urban nonindustrial areas (24.58 ± 10.32, 7.24 ± 6.31, and 2.47 ± 3.32 µg/dL, respectively; p <0.001). Weight-forage z-scores of the urban children were significantly lower than that of the rural children (-1.41 ± 1.88 vs. 0.20 ± 1.16, p <0.001). Children with elevated BLLs had poorer nutritional status (p = 0.05) than those with normal BLLs. Over 90% of the parents did not know that lead causes health problems. In conclusion, the problem of lead poisoning in children was found to be high in both urban and rural Bangladesh. A universal lead screening for preschool and school-aged children and a lead education program for parents are recommended for implementation in Bangladesh.
2013
Dhaka, Bangladesh, has one of the highest air lead levels in the world. In February 2000, we evaluated children at five primary schools in Dhaka to determine blood lead (BPb) levels, sources of environmental exposure, and potential risk factors for lead poisoning. Selected schools represented a range of geographic and socioeconomic strata. A total of 779 students 4–12 years of age participated. The mean BPb level was 15.0 µg/dL (range 4.2–63.1 µg/dL). Most students (87.4%) had BPb levels above the Centers for Disease Control and Prevention’s level of concern (10 µg/dL). Elevated BPb levels correlated with soil eating [odds ratio (OR) = 3.31; 95 % confidence interval (CI), 1.30–8.39], low parental education (OR = 2.72; 95 % CI, 1.97–3.75), living close to major roads (OR = 2.30; 95 % CI, 1.23–4.29), and increasing age (OR = 1.11; 95 % CI, 1.06–1.16). BPb levels measured were similar to those in other countries that use leaded gasoline. No other potential sources of lead exposure were...
Journal of Health, Population and Nutrition, 2013
Lead poisoning is a major public-health problem in Bangladesh. A cross-sectional study was conducted to determine the extent of and risk factors for elevated blood lead levels (BLLs) in children in Bangladesh during September 2007-July 2009. The study included 919 children aged less than 16 years. The children were recruited from six urban locations in Dhaka and one rural area in Chirirbandar, Dinajpur. In total, 495 (54%) children had high BLLs (>10 µg/dL), with higher BLLs observed among children aged 5-9 years compared to children of other ages (p<0.001). The BLLs among children in urban Dhaka were significantly higher than those in rural areas (13.45±8.21 µg/dL vs 7.29±6.25 µg/dL, p<0.001). The high BLLs correlated with low body mass index (r=-0.23, p<0.001) and low haemoglobin status (r=-0.10, p=0.02). On bivariate analysis, proximity to industry (p<0.001), drinking-water from municipal supply or tubewell (p<0.001), brass or lead water-taps (p<0.001), use of melamine plate (p=0.001), and indigenous medicinal (kabiraji) treatments (p=0.004) significantly correlated with higher BLLs. Proximity to industry and the use of indigenous medicines remained significant predictors of high BLLs after controlling for the confounders. Several risk factors appropriate for future educational interventions to prevent exposure to lead poisoning were identified.
Environmental Research, 2010
Lead is a well-known neurotoxic metal and one of the most toxic chemicals in a child's environment. The aim of this study was to assess early-life lead exposure in a pristine rural area of Bangladesh. The exposure was expected to be very low because of the absence of vehicle traffic and polluting industries. Lead was measured in erythrocytes, urine, and breast milk of 500 randomly selected pregnant women, participating in a randomized food and micronutrient supplementation trial in Matlab (MINIMat). Lead was also measured in urine of their children at 1.5 and 5 years of age, and in rice, well water, cooking pots, and materials used for walls and roof. All measurements were performed using ICPMS. We found that the women had relatively high median erythrocyte lead levels, which increased considerably from early pregnancy to late lactation (81-136 mg/kg), probably due to release from bone. Urinary lead concentrations were unchanged during pregnancy (median $ 3.5 mg/L) and non-linearly associated with maternal blood lead levels. Children, at 1.5 and 5 years of age, had a median urinary lead concentration of 4 mg/L, i.e., similar to that in their mothers. Rice, the staple food in Matlab, collected from 63 homes of the study sample, contained 1-89 mg/kg (median 13 mg/kg) dry weight and seems to be an important source of lead exposure. Other sources of exposure may be cooking pots and metal sheet roof material, which were found to release up to 380 and 4200 mg/L, respectively, into acidic solutions. Based on breast milk lead concentrations (median 1.3 mg/L) a median daily intake of 1.2 mg was estimated for 3 months old infants. However, alternatives to breast-feeding are likely to contain more lead, especially rice-based formula. To conclude, lead exposure in women and their children in a remote unpolluted area was found to be surprisingly high, which may be due to their living conditions.
PLOS ONE, 2022
Lead is one of ten hazardous chemicals of public health concern and is used in more than 900 occupations, including the battery, smelting, and mining industries. Lead toxicity accounts for 1.5% (900,000) of deaths annually in the world. In Indonesia, reports of high Blood Lead Level (BLL) were associated with residency in Used Lead Acid Battery (ULAB) recycling sites. The present study aims to investigate the BLL and the evidence of lead toxicity of children living in an ULAB recycling site in Bogor Regency, Indonesia. A cross-sectional study involving 128 children aged 1–5 years was conducted in September-October 2019. The socio-economic factors, BLL, nutritional status, and hematological parameters, were evaluated. Data were analyzed by univariate and bivariate using the Chi-Square test. Socio-economic factors revealed only 2.3% children have pica and 10.9% children have hand-to-mouth habits. Majority of parents had low income, education, and have stayed in the village for years. ...
Asia-pacific Journal of Public Health, 2000
The objective of this article is to study the influence of exposure and socio-economic variables on the blood lead level of Malaysian school children. Data on respirable lead and blood lead of 346 school children were obtained from Kuala Lumpur (urban), Kemaman (semiurban) and Setiu (rural). Respirable lead and blood lead were highest for Kuala Lumpur (95 ng/m 3 and 5.26 μg/dL) followed by Kemaman (27 ng/m3 and 2.81μg/dL) and Setiu (15 ng/m 3 and 2.49 μg/dL), and the differences were statistically significant. The percentage of school children with excessive blood lead of 10 μg/dL or greater was 6.36 % overall, and highest for Kuala Lumpur (11.73 %). Regression analyses show that urban children are at higher risk of exhibiting excessive blood lead levels. Kuala Lumpur's school children have a 25 times greater risk of having excessive blood lead levels when compared to Kemaman's and Setiu's school children. Respirable and blood lead were correlated ( r =0.999, p =0.021).
PloS one, 2018
Elevated blood lead level (BLL) is known to cause cardiac, immune, and cognitive damage but had not been thoroughly studied in relation to stunting among children under two years of age. We primarily aimed to assess the relationship between elevated BLL, the accumulation of concerned amount of the metal lead in blood and stunting and secondarily-wasting and underweight amongst Bangladeshi children less than two years of age. For this cross-sectional study, BLL measurements, anthropometric data, and socioeconomic indicator information were collected and analyzed for 729 children under two years of age upon enrollment in the MAL-ED study conducted in a Bangladeshi slum area. Univariate, bivariate and multivariate analyses were carried out to observe the proportion and mean and contribution of elevated BLL and other relevant variables in explaining the occurrence of stunting. Of the enrolled subjects, 39.0% were stunted [length-for-age z score (LAZ<-2)], 50.3% were male, and 86.6% h...
Turkish Journal of Biochemistry, 2021
ObjectivesLead exposure in children contributes to 600,000 new cases of intellectual disabilities every year with maximum occurrence in developing countries. Currently limited information is available on the blood lead level (BLL) in children of India. The aim was to estimate BLL in the school going children of local population of Jodhpur.MethodsFour hundred twenty-six primary school children of government and private schools participated in this cross sectional study. Information regarding possible lead exposure was collected. BLL was estimated on Lead Care II analyser (Magellan Diagnostics, USA).ResultsThe mean and median BLL were 4.25 ± 1.75 μg/dL (<3.3–22.6 μg/dL) and 3.5 μg/dL (Inter Quartile Range 0.9). BLL was higher in children of illiterate mothers, those residing near traffic dense areas, urban region and studying in government schools of urban region.ConclusionsBLL in children residing in Jodhpur is much higher in comparison to western counterparts. Screening and aware...
The Southeast Asian journal of tropical medicine and public health, 2014
A community-based study was conducted to determine personal risk factors and environmental sources of lead exposure for elevated blood lead levels (≥ 10 µg/dl, EBLLs) among rural children living at the Thailand-Myanmar border in Tak Province, northwestern Thailand. Six hundred ninety-five children aged 1-14 years old were screened for BLLs. Environmental specimens for lead measurements included samples of water from the streams, taps, and household containers, house floor dust, and foods. Possible lead release from the cooking ware was determined using the leaching method with acetic acid. The overall prevalence of EBLLs was 47.1% and the geometric mean level of blood lead was 9.16 µg/dl. Personal risk factors significantly associated with EBLLs included being male, younger age, anemia, and low weight-for-age. Significant environmental risk factors were exposure to a lead-acid battery of solar energy system and use of a non-certified metal cooking pot. Some families whose children h...
Risk analysis, 2005
This research was initiated to study lead levels in various food items in the city of Kanpur, India, to assess the dietary intake of lead and to estimate blood lead (PbB) levels, a biomarker of lead toxicity. For this purpose, sampling of food products, laboratory analysis, and ...
PloS one, 2017
Young children are at greatest risk of exposure to lead and its effects. Although lead is one of the most widely used elements with known health hazard, there is little data on the blood lead level (BLL) of children in the Kathmandu Valley. Thus, this study aimed to assess factors associated with high BLL in children who were 6-36 months of age and resided in the Kathmandu Valley. In this hospital-based cross-sectional study 6-36 month-old children visiting the Paediatrics Outpatient Department of Tribhuvan University Teaching Hospital, Patan Hospital, and Siddhi Memorial Hospital were enrolled. All three hospitals are located in different areas inside the Kathmandu Valley. Written informed consent was obtained from the parents, and exposure data were collected using a structured questionnaire. Portable Anodic Stripping Voltammetry (ASV) was used to determine BLLs in children. Data were analyzed using SPSS version 16. Of 312 children enrolled in the study, 64.4% had BLLs ≥5μg/dl. A ...
Indian Journal of Medical Sciences, 2008
CONTEXT: Lead is a major health hazard, especially in children. Impact of lead poisoning on our society is not known. Effectiveness of environmental interventions in reducing blood lead levels is not exactly known, though the Center for Disease Control and Prevention strongly advocates use of such means. AIMS: We aimed at screening school children for blood lead levels (BLLs) and reducing the BLLs of children with preliminary BLL >20 µg/dL by environmental intervention and intensive education. MATERIALS AND METHODS: To assess the extent of lead poisoning, a screening of 106 children was done, which showed that children belonging to a particular government primary school had higher BLLs. A second screening program of 87 children conducted in that school showed that only 19% had BLL <10 µg/dL; whereas 44% had BLL between 10 and 20 µg/dL, and 37% had BLL >20 µg/dL. Thirty-eight children having BLL >20 µg/dL were selected from the two screening programs. After removing all potential sources of lead from their environment and educating them about the ways to prevent exposure to lead, follow-up of their BLLs was carried out at an interval of 6 months for a period of 1 year. STATISTICAL ANALYSIS: Values of the different follow-up studies were compared using repeated-measure ANOVA. RESULTS: Our results showed that there was a significant (P <0.0001) reduction in the BLLs in the first and second follow-up studies. The study is a proof of the concept that a decline in the BLLs can be achieved by intense education and avoiding the potential environmental sources of lead.
Journal of the Medical Association of Thailand Chotmaihet Thangphaet, 2011
Background: Centers of Disease Control of the United Slates of America (CDC) informs Ministry of Public Health, Thailand that up to! 3% of Burmese refugee children who are transferred to the United States of America during 2007-2009 have elevated blood lead levels (EBLL, Blood Lead Level >_ 10 fJg/dl). These are children from a number of refugee camps in Tak Province; two camps are near Umphang but other camps are not. In.June 2008, CDC, the result of investigation of Centers for Disease Control/Thailand Ministry of Public Health Collaboration (CDC/TUC) and International Organization for Migration. Thailand indicates thai 33 of 64 children aged 6 months to 15 years (5.1 %) who live in Mae La, Umpiem and Nupo camps have elevated blood lead level. However, no study on how Thai children who live nearby those camps are exposed to lead. Subsequently, Queen Sirikit National Institute of Child Health, Bangkok, Thailand contacts relevant organizations in Tak Province in order to investigate lead exposure and evaluate health status of Thai children who live close to Burmese refugee camps. Objective: I) Evaluation of lead exposure of Thai children who live nearby Burmese refugee camps; 2) Assessment of risk factors on lead exposure of the children as mentioned above. Material and Method: The present study adopts a retrospective study based on information gathered from health assessment on 213 Thai children aged between 3-7 years old who live nearby Burmese refugee camps. The health assessment was conducted from April 30"", 2010 to May 5"', 2010. The information is from 3 sources. The first source is from blood sampling in order to assess lead level and ferritin level The next source is from interview ofpersons who provide primary care in order to identify risk factors on lead exposure of target children. The last source is from physical examination and developmental assessment conducted by pediatricians and special nurses for child development in order to identify health and developmental problems. Results: The population of the present study was 213 of Thai children are 3-7 years old, average age is 54.54 + 12.41 monthsold. The average blood lead level is 7.72 ±4.62 jjg/dl (range = 3-25 i^g/dt). Elevated blood lead levels of all populations show that 57 children (26%) have blood lead level at 10 }J.g/dl or more. Analysis of odds by controlling all risk factors (adjusted OR) that effect on blood lead level (>10^gldl) indicates that only gender and source of drinking water are risk factors. To clarify, male children would have 2.8 times higher risk than female children. Children who drink water from tap and canal have 15 times and 72 times, respectively, higher risk than children drinking from bottle water. Conclusion: The result of the present study shows that 1 of 4 of Thai children at Umphang district, Tak Province who lived near Burmese refugee camps aged between 3-7 years old have blood lead level higher than concerning level. Thus, it is necessary to identify risk factors on lead exposure and policy of blood lead screening in some areas in Thailand.
International journal of health sciences
Karbala provides theoretical assistance for lead pollution prevention by determining blood levels and identifying relevant risk factors among adolescents. Blood lead levels determine by Graphite Furnace Atomic Absorb piton Spectrometry (GFAAS) result. Methods blood samples were taken from both males and females. A total of 100 subjects (average age of 13-17 years, 8 females, and 92 males) were included. The arithmetic means, sample characteristics between two levels of lead concentrations (Less than 100µg/L lead concentration and more or equal 100µg/L lead concentration were patients their number 50 and control also 50 Mean ± SE 49.36 ± 6.61 patients mean ± SE 184.18 ± 6.61 control. Education, His relationship with his parents, Living, Smoking. (T= 7.79**, 4.39**, 4.30**, 4.87**, resp.), while Samples Patients and control (T=18.86**).Conclusions. The levels of lead in the blood of adolescents 13 to 17 years in Karbala governorate were higher than in other areas due to leaving scho...
Water, Air, & Soil Pollution
Lead (Pb) is a widely occurring heavy metal employed in industrial products and hence released into the environment, causing several environmental health risk concerns. This study comprehensively surveyed the literature on Pb contamination in different agricultural foods and food products commonly consumed by Bangladeshi inhabitants and assessed associated cancer and non-cancer health risks. Cereals (i.e., rice, wheat and maize) contained very high concentrations of Pb among the selected food items, the highest was found in wheat (4.04 µg g−1), while rice and maize were 2.22 and 1.43 µg g−1, respectively, that exceeded the maximum allowable concentration (MAC, 0.20 µg g−1) for cereals. Vegetables contained higher Pb than the MAC of 0.01 µg g−1, except for mushroom, green banana, cauliflower and arum. In addition, pulses also contained a moderate amount of Pb; however, fruits contained a low level of Pb, except for mangoes. When examining spatial differences in Pb contamination, most...
Journal of Health & Pollution, 2021
Background. Lead (Pb) poses a severe threat to human health and the environment. Worldwide Pb production and consumption have significantly increased along with unplanned industrialization and urbanization, lead smelting, and lead-acid battery processing. The improper management of Pb-containing elements is responsible for Pb pollution. Lead's persistence in nature and bioaccumulation in the food chain can lead to adverse health impacts. Objectives. The present study aims to describe Pb contaminated sites in Bangladesh and Pb concentration in the atmosphere, water, sediments, soil, vegetables, fish, and other foods in Bangladesh. Methods. The present study searched a total of 128 peer-reviewed articles based on a predefined set of criteria (keywords, peer-reviewed journals, and indexing in Scopus, Science Direct, Web of Science, Springer, PubMed, Directory of Open Access Journals (DOAJ), and Bangladesh Journals Online (BanglaJOL) and exclusion criteria (predatory journal and abs...
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