Serratia plymuthica: A community-acquired uropathogen

Journal of Health Sciences and Medicine

Serratia marcescens (S. marcescens), Enterobactericea ailesinde yer alan Gram negatif basil olup, sağlık bakımı ile ilişkili infeksiyonlar ve yoğun bakımda salgınların önemli bir etkenidir. Bu yazıda yoğun bakımda yatarken S. marcescens'e bağlı olarak bakteremik üriner sistem infeksiyonu gelişen kalıcı idrar sondası olan yatağa bağımlı 82 yaşında bir kadın hasta sunularak literatür gözden geçirildi. Sonuç olarak, özellikle kalıcı idrar sondası olan yatalak hastalarda S. marcescens ve diğer Gram nagatif bakterilerin bakteriyemi ile seyreden üriner sistem infeksiyonlarına neden olabileceği akılda tutulmalı ve bu hastalarda idrar kültürü ile birlikte kan kültürleri de alınmalıdır.

Journal of Clinical Microbiology, 1994

We report a case of nosocomial septicemia in a 79-year-old patient caused by Serratia plymuthica with no evident focus of infection. The patient was treated with gentamicin (40 mg every 8 h) during 10 days; clinical resolution of the infection was obtained after the 10-day treatment period.

European Journal of Clinical Microbiology & Infectious Diseases, 2011

Objective We aimed to present our experience regarding infections caused by Serratia 32 spp. in a region with relatively high antimicrobial resistance rates. 33

European Journal of Internal Medicine, 2003

This case report describes an uncommon cellulitis caused by Serratia plymuthica in a patient treated with steroids. The evolution was favorable after surgical exploration with debridement and antibiotic treatment. This is the first case of necrotic cellulitis caused by S. plymuthica described in the literature.

Journal of Clinical Microbiology, 2003

Chang Gung Memorial Hospital, Taoyuan, Taiwan. A review of laboratory (1991 to 2002) and infection control (1995 to 2002) records showed the possibility of an extended epidemic of nosocomial urinary tract infections (UTIs) caused by S. marcescens. Therefore, in 1998 and 1999, 87 isolates were collected from patients with such infections and examined and another 51 isolates were collected in 2001 and 2002. The patients were mostly elderly or the infections were associated with the use of several invasive devices. S. marcescens was usually the only pathogen found in urine cultures in our study. Neither prior infections nor disseminated infections with the organism were observed in these patients. Resistance to most antibiotics except imipenem was noted. Two genotyping methods, pulsed-field gel electrophoresis and infrequent-restriction-site PCR, were used to examine the isolates. A total of 12 genotypes were identified, and 2 predominant genotypes were found in 72 (82.8%) of the 87 isolates derived from all over the hospital. However, 63.9% of the isolates of the two genotypes were from neurology wards. A subsequent intervention by infection control personnel reduced the infection rate greatly. The number and proportion of the two predominant genotypes were significantly reduced among the 51 isolates collected in 2001 and 2002. Thus, a chronic and long-lasting epidemic of nosocomial UTIs caused by S. marcescens was identified and a successful intervention was carried out. Both a cautious review of laboratory and infection control data and an efficient genotyping system are necessary to identify such a cryptic epidemic and further contribute to the quality of patient care. on July 1, 2015 by guest http://jcm.asm.org/ Downloaded from 4730 SU ET AL.

Journal of Evolution of medical and Dental Sciences, 2014

INTRODUCTION: Serratia marcescens is a member of the Entero bactereacae family. S. marcescens is widely distributed in nature. It is isolated as saprophytes from soil and water. Reports of nosocomial infections caused by S. marcescens have increased in recent years. Infections include UTI, RTI, Septicaemia, Meningitis and Endotoxic shock. Only small proportion (<10%) of strains responsible for infection are pigmented. It is the most common clinical isolate among Serratia2.We isolated Serratia marcescens from blood culture of a hospitalized patient who was hospitalized for diabetes mellitus and chronic diarrhea.

JMM Case Reports, 2014

Introduction: Serratia marcescens is a Gram-negative, aerobic, motile bacillus belonging to the family Enterobacteriaceae. S. marcescens has been implicated in different types of infections including urinary tract infection, septicaemia, meningitis and wound infections. Very few cases of skin infections caused by this organism have been reported in the medical literature. S. marcescens is an important nosocomial pathogen but has rarely been implicated as a cause of community-acquired soft-tissue infections. Case presentation: We present a rare case of a community-acquired spontaneous cutaneous ulcer in an immunocompetent child from a sub-Himalayan region. Infections caused by S. marcescens may be difficult to treat because of its ability to produce a b-lactamase, which confers resistance to broad-spectrum, b-lactam antibiotics. Conclusion: In our patient, the treatment was modified to ceftazidime and amikacin after sensitivity testing and the patient's condition improved. This necessitated isolation by culture and antimicrobial susceptibility testing to ensure appropriate therapy.

Open Journal of Nephrology, 2022

We present the 3 rd known case of a Serratia rubidaea urinary tract infection in a 49-year-old male with past medical history of bilateral lower extremity paraplegia who presented to the emergency room with fever, lethargy, and red tinted urine. The Serratia genus, of the family Enterobacteracia, in particular the species Serratia marcescens, are important causes of infection in humans, animals, and insects, however, until the mid-1950s, this was not the case, and the organism was considered non-pathogenic and frequently used in medical experiments. Serratia are facultatively anaerobic, gram-negative rods, the majority with peritrichous flagella primarily inhabiting soil, water, and plant surfaces. Serratia marcescens is now a known pathogen, however, less frequently isolated species, including Serratia rubidaea, are worthy of discussion, especially due to its characteristic red color and rarity. We aim to increase the awareness Serratia rubidaea including its presentation, inherent antimicrobial resistance, and treatment options.

Future Microbiology, 2012

Aims: We explored changes in antibiotic susceptibility of Serratia marcescens in the last 50 years by comparing isolates collected between 1945 and 1950, and current isolates. Materials & methods: Isolates were divided into three groups: environmental, clinical and ‘old’. Susceptibility was determined by microdilution. Class 1 integrons were determined by PCR. Statistical analysis was conducted using the Kruskal–Wallis (K–W) tests with Bonferroni correction for multiplicity. Antimicrobials showing differences in the K–W test were analyzed by Mann–Whitney U test. Differences were considered significant when p < 0.05. Results: All isolates were sensitive to ceftazidime, cefotaxime, kanamycin, gentamicin, ofloxacin and ciprofloxacin, and resistant to rifampicin, penicillin, ampicillin, amoxicillin, tetracycline, amoxicillin–clavulanic acid, cefazolin, cefamandole, polymyxin B/colistin, fusidic acid, lincosamides, streptogramins, daptomycin, linezolid and cefuroxime. Old isolates exh...

Journal of Clinical Microbiology

The first isolation of Serratia ficaria from a human source is reported.