Nasal Ulceration Reveling Multifunctional Tuberculosis

Scholars Journal of Medical Case Reports

Tuberculosis is still endemic in developing countries. Nasal tuberculosis is a rare chronic infection, it remains a diagnostic challenge. We report the case of a 59-year-old female patient with multifocal tuberculosis (nasal, pulmonary, and lymph nodes). The revealing symptom of her illness was a progressive nasal obstruction with anosmia and intermittent pus discharge through the lacrimal duct. The diagnosis was retained in view of the epidemiological context, chronic crusted and purulent rhinitis that did not improve with antibiotics, presence of granulomatous lesions on nasal biopsy and detection of acid-alcohol resistant bacilli on direct examination of bronchial aspirates. The patient was treated with antituberculosis therapy for 9 months with complete recovery. Given the resurgence of tuberculosis in recent times, it is important that clinicians remain aware of this rare and treatable clinical entity.

Caspian Journal of Internal Medicine, 2014

Background: Nasal tuberculosis (NTB) is rare, but it can be caused by either a pulmonary disease or a retrograde involvement of the nose by lupus vulgaris of the facial skin. In this study, we present a case of NTB with an ulcerative lesion in her left nasal cavity. Case presentation: A 56 years old woman presented with an ulcerative lesion in her left nasal cavity. The patient exhibited no clinical evidence of any systemic diseases. Peripheral leucocyte count (CBC) was normal but erythrocyte sedimentation rate was elevated. Mantoux' test elicited 25 mm reaction after 72 hr. Chest x-ray was normal. Pathological evaluation of the lesion revealed the caseating granulomas, epithelioid cells, lymphocytes, and a few giant cells. These findings suggested a diagnosis of tuberculosis. The patient was cured after 6 months treatment with standard regimen of tuberculosis. Conclusion: Although, nasal tuberculosis is rare, it should be considered in the differential diagnosis of patients with chronic nasal symptoms and ulcerative lesions of the nose.

American Journal of Health Research, 2014

Vojnosanitetskog pregleda izašao je septembra meseca 1944. godine asopis nastavlja tradiciju Vojno-sanitetskog glasnika, koji je izlazio od 1930. do 1941. godine IZDAVA Uprava za vojno zdravstvo MO Srbije

2020

Background: Primary nasal tuberculosis (TB) is a rare form of Tuberculosis even in country like India which had a high incidence of Tuberculosis. Moreover, the diagnosis and proper management of Nasal tuberculosis has often delayed as it is rare and presents with nonspecific clinical picture. Case Presentation: A 47 years old man presented with a soft sessile mass in nasal cavity. The patient has no clinical evidence of any systemic diseases. Complete blood count (CBC) was normal with raised erythrocyte sedimentation rate. Chest x-ray was normal. The lesion revealed caseating granulomas, epithelioid cells, lymphocytes, and a few giant cells on histopathological examination suggestive of Tuberculosis. Anti-Tubercular therapy (ATT) was given and followed for 6 month and patient was cured. Conclusion: Although, nasal tuberculosis is rare, one should be skeptic in the differential diagnosis of patients with chronic nasal symptoms and mass like lesion of the nose.

Rawal Medical Journal, 2013

place a major challenge in its diagnosis and We present a case of nasal tuberculosis, a rare treatment. (Rawal Med J 2013;38:81-83). presentation of extra-pulmonary tuberculosis.

Revue de …, 2007

We report a case of a 36 year old woman who presented a chronic rhinitis and a hypertrophy of the inferior turbinates. Primary nasal tuberculosis was discovered by chance after the inferior turbinectomy. Primary nasal tuberculosis is very rare and is more frequent in women. ...

2014

Tuberculosis is one of the most important infectious diseases. In 2009 estimate 9 million new cases were registered worldwide, mortality due tuberculosis reached 1.5 million (Markowski et al., 2011). Tuberculosis may infect any part of the body, but most commonly occurs in the lungs (known as pulmonary tuberculosis) (Dolin et al., 2010). Extra pulmonary TB occurs when tuberculosis develops outside of the lungs. Extra pulmonary TB may coexist with pulmonary TB as well (Dolin et al., 2010). The under diagnosis of extra pulmonary tuberculosis lesions, along with an emerging global resistance to antitubercular drugs, warrants an increased awareness of the involvement of Mycobacterium tuberculosis in atypical lesions (Yadav et al., 2012).

Medical Journal of Dr. D.Y. Patil University, 2014

International Journal of Otorhinolaryngology and Head and Neck Surgery, 2017

Background: Tuberculosis has become a common occurrence in Otorhinolaryngology with increasing number of extra pulmonary cases. Methods: This is a study of 27 patients who visited ENT OPD of Dr. D. Y. Patil Medical College, Pune, with variety of manifestations of tuberculosis in the ENT region. Results: Majority of those suffered from tuberculous cervical lymphadenopathy, other manifestations included laryngeal tuberculosis, tuberculous otitis media, lupus vulgaris and tuberculous infection of a pre auricular sinus. FNAC and histopathologic examination proved to be reliable tools of diagnosis. Five of these patients suffered from concurrent pulmonary tuberculosis. All these responded well to category 1 anti-tubercular therapy well. Conclusions: Tuberculosis in Otorhinolaryngology shows a variety of manifestations so it should be kept in mind whenever dealing with unusual presentations.

Intractable & Rare Diseases Research, 2016