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The aim of this study is to analyze the factors associated with sleep quality in people living with HIV/AIDS (PLHA). It is a cross-sectional study with 314 PLHA. The Pittsburgh Sleep Quality Index was used to assess sleep quality. Socioeconomic, clinical and lifestyle habits were investigated through a structured anamnesis. Using the bivariate analysis, the differences between the sleep quality components in relation to the independent study variables were verified (p <0.10). Linear regression was performed following a multilevel hierarchical model for each sleep quality component (p ≤ 0.5). Regarding the sleep quality domains, there was an association with socioeconomic and clinical factors. Sleep latency with marital status; usual efficiency with marital status and use of HAART and sleep disorders with schooling. The study concludes that sleep latency and usual efficiency in PLHA are associated with marital status, while sleep quality with gender and sleep disturbance with scho...
2020
Background: Sleep disturbance is a common complaint in people living with HIV/AIDS. Individuals with it are less likely to adhere to their treatment, have decreased quality of life, have decreased work productivity, and have increased risk of psychiatric disorders, cardiovascular morbidity, and disease progression. However, sleep condition remains under-recognized by clinicians and is not well studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the clinical knowledge gap and recommend the focus area of management. The aim of the study was to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods: An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint e...
2022
Background Sleep is a natural, restorative, physiological process that is characterized by perceptual disengagement from and unresponsiveness to whatever going around, which is reversible. Sleep quality refers to a sense of being rested and refreshed after waking up from sleep. People living with HIV/AIDS (PLWHA) are vulnerable to poor sleep quality as they suffer from social stigma and Anti-Retroviral drug side effects. The study aimed to examine the quality of sleep and its associated factors among people living with HIV/AIDS attending Anti-Retroviral Therapy (ART) clinic at Hawassa University comprehensive specialized hospital. Method Institutional based cross-sectional study was conducted among PLWHA attending ART clinic at Hawassa University comprehensive specialized hospital from May 1-30, 2019. A systematic random sampling technique was used to select an estimated 422 study participants and data was collected using interviewer-administered technique. Sleep Quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Data were entered and analyzed using SPSS 22 software. Bivariable and multivariable logistic regression model was fitted to identify factors associated with quality of sleep. An adjusted odds ratio with a 95% confidence interval was computed to determine the level of significance with P-value less than 0.05. Result Out of 422 respondents, 389 participated in the study giving a response rate of 92.1%. The prevalence of poor quality of sleep among study participants was found to be 57.6% (95% PLOS ONE
AIDS and Behavior, 2018
Short and long sleep durations have been associated with inflammation and chronic diseases. To study the association between sleep duration/quality and HIV disease severity, a cross-sectional study was conducted in patients living with HIV (PLWHs) using self-administered questionnaires assessing total sleep time, insomnia (ICSD-3 criteria), and poor sleep quality (PSQI > 5). Multivariable logistic regression identified the factors associated with sleep disorders and with HIV features. 640 Parisian ambulatory PLWHs were included. The prevalence of insomnia was 50 and 68% of patients had a PSQI > 5. Patients with CD4 count < 500 cells/mm 3 were more likely to be long sleepers (> 8 h/day) (OR 1.49; 95% CI [1.10-1.99]: p < 0.01), and less likely to be short sleepers (< 6 h/day) (OR 0.69; 95% CI[0.50-0.96]; p = 0.04) or to experience insomnia (OR 0.59; 95% CI[0.40-0.86]; p < 0.01). HIV features were not associated with a PSQI > 5. Thus, insomnia and impaired sleep quality were highly prevalent in well-controlled PLWHs and the severity of HIV infection was associated with long sleep times.
Journal of Clinical Sleep Medicine, 2000
Objective: To characterize specifi c types of sleep problems experienced by adults with HIV. Method: The design was cross-sectional involving sleep questionnaires, diaries, and wrist actigraphy. The convenience sample included 290 adults living with HIV, 22-77 years of age. Measures included self-report for sleep onset latency, and wrist actigraphy estimates of total sleep time at night, wake after sleep onset, and daytime sleep. Results: Nearly half (45%) of the sample slept < 6 h per night. Diffi culty falling asleep was reported by 34%, and 56% had fragmented sleep according to actigraphy; 20% had both problems, and 30% were good sleepers. Participants reporting diffi culty falling asleep had actigraphy and clinical measures similar to the good sleepers, but subjectively they experienced greater sleep disturbance and symptom burden (particularly anxiety and morning fatigue) and reported more use of sleep medication. Participants with fragmented sleep reported low levels of sleep disturbance and symptom burden similar to the good sleepers, despite actigraphy measures indicating they obtained less sleep both at night and during the day. Sleep fragmentation was also associated with sociodemographic factors and slightly lower CD4+ T-cell counts. Participants reporting both sleep problems had actigraphy and clinical profi les similar to those who had only fragmented sleep, but their symptom experience was similar to participants with only sleep initiation diffi culties. Conclusions: Findings support the need for targeting efforts to improve sleep for the majority of adults living with HIV/AIDS and tailoring interventions to the specifi c type of sleep problem regardless of the person's clinical and demographic profi le.
Journal of Clinical Medicine
Objectives: Sleep disturbances are prevalent problems among human immunodeficiency virus (HIV)-infected persons. The recognition of comorbid sleep disorders in patients with HIV is currently hampered by limited knowledge of sleep-related symptoms, sleep architecture, and types of sleep disorders in this population. We aimed to compare the differences in sleep-related symptoms and polysomnography-based sleep disorders between HIV-infected persons and controls. Methods: The study evaluated 170 men with a Pittsburgh sleep quality index scores greater than 5, including 44 HIV-infected men and 126 male controls who were frequency-matched by sex, age (±3.0 years) and BMI (±3.0 kg/m2). For all participants, an overnight sleep study using a Somte V1 monitor was conducted. Differences in sleep-related symptoms and sleep disorders between HIV-infected patients and controls were examined using t-tests or chi-square tests. Results: HIV-infected persons with sleep disturbances more often had psy...
https://www.ijrrjournal.com/IJRR_Vol.8_Issue.10_Oct2021/IJRR-Abstract03.html, 2021
Background/aim: People with HIV are often reported to experience poor sleep quality. Factors that can cause poor sleep quality in HIV patients, including the use of ARV therapy. The pathophysiology of poor sleep quality in HIV patients is still unclear. Poor sleep quality is one of the complaints in the late stages of HIV infection, where it is suspected that HIV itself affects the biological center of sleep. This study was aimed to determine the comparison of sleep quality in HIV patients pre-HAART and with HAART more than 1 year. Method: This study uses data collection methods in the form of interviews with samples which will later be presented in the form of analytical observational study. Consecutive data collection on HIV patients before and after ARV therapy who was outpatient at the VCT outpatient clinic Dr. Soetomo General Hospital from June-July 2021. Data analysis using SPSS Version 23 for windows Results: A total of 40 subjects were divided into HIV pre-HAART and on HAART. From the statistical analysis using SPSS program significant with p=0.004 (OR 15.5 (95% CI (1.73-139.6)) Conclusion: HIV patients on HAART for more than 1 year are known to have increased 15.5 times the risk of poor sleep quality
2020
Background Sleep disturbance is the leading health problem in the era of HIV/AIDS. The exact cause of sleep disturbance was not well known, but it is related to HIV itself, antiretroviral drugs side effect, and other HIV related disorders. This study aimed to assess the prevalence of sleep disturbance and associated factors among adult people living with HIV/AIDS. Methods A cross-sectional study was conducted. A total of 419 study participants participated in the study. A systematic random sampling method was employed. An interviewer-administered a method of data collection with a chart review was used. Pittsburg Sleep Quality of Index for assessing sleep disturbance was used. A binary logistic regression was conducted. The variables having a p-value
Aids and Behavior, 2015
This cross-sectional study evaluates the prevalence and factors associated with sleep disturbances in French adult HIV-infected outpatients. Patients fullfilled a self-administered questionnaire on their health behavior, sleep attitudes (Pittsburgh sleep quality index, PSQI), quality of life and depression; 1354 patients were enrolled. Median sleeping time was 7 h. Poor sleep quality was observed in 47 % of the patients, and moderate to serious depressive symptoms in 19.7 %. Factors significantly associated with sleep disturbances were depression, male gender, active employment, living single, tobacco-smoking, duration of HIV infection, nevirapine or efavirenzincluding regimen. Prevalence of poor sleepers is high in this HIV adult outpatient population. Associated factors seem poorly specific to HIV infection and more related to social and psychological status. Taking care of these disturbances may prove to be an effective health management strategy. Resumen Este estudio transversal evalúa la prevalencia y los factores asociados con los trastornos del sueño en adultos franceses pacientes en ambulatorio infectados por el VIH. Los pacientes completan un auto-cuestionario sobre su comportamiento de salud, las actitudes del sueño (Pittsburgh Sleep Quality Index, PSQI), la calidad de vida y la depresión; 1354 pacientes fueron incluidos. La mediana del tiempo de sueño fue de 7 horas. La malacalidad del sueño se observó en el 47 % de los pacientes, y moderados a graves síntomas depresivos en 19,7 % de los pacientes. Los factores asociados significativamente con las alteraciones del sueño son: la depresión, el sexo masculino, trabajador activo, viviendo solo, fumador, la duración de la infección VIH, tratamiento nevirapina o efavirenz. La prevalencia de los trastornos del sueño es alta en esta población de pacientes adultos VIH en ambulatorio. Los factores asociados parecen poco relacionados a la infección VIH y más relacionados con el estatus social y psicológico. El cuidado de estos trastornos puede ser una estrategia eficaz en la gestión de la salud. Keywords Sleep disturbance Á Insomnia Á Depression Á HIV infection The members of COREVIH-Pays de la Loire Troubles du Sommeil Study Group are listed in Appendix.
BMC Psychiatry
Background Poor sleep quality is an important health problem in people living with HIV. The exact cause of sleep disturbance is not well known, but it may relate to HIV itself, antiretroviral drug side effects, and other HIV-related disorders. As a result, the purpose of this study was to assess sleep quality and associated factors among adult HIV patients on follow-up at Dessie Town governmental health facilities’ antiretroviral therapy clinics in Northeast Ethiopia in 2020. Methods A multi-center cross-sectional study was conducted among 419 adult people living with HIV/AIDS from February 1/2020 to April 22/2020 in Dessie Town governmental antiretroviral therapy clinics. A systematic random sampling method was used to select the study participants. An interviewer-administered method of data collection with a chart review was used. The Pittsburgh Sleep Quality Index was used to evaluate sleep disruption. A binary logistic regression was conducted to see the relationship between a d...
ijhssnet.com
The negative effects of sleep disturbances have been well documented in the general population and research shows individuals with the Human Immunodeficiency Virus (HIV) are particularly vulnerable to sleep difficulties. The medical and life quality issues effecting this population indicate the importance of characterizing the nature of these difficulties in terms of both sleep quality and quantity. With the extended life expectancies of HIV-positive persons, management of problems such as sleep disturbance is a vital aspect of improving quality of life. This study examined the sleep habits of persons living with HIV to determine sleep quality and identify possible targets for intervention. Results indicated that HIV-positive persons suffer diminished quality of sleep, high levels of insomnia, and high levels of nocturnal awakenings. Implications are discussed.
Journal of the Association of Nurses in AIDS Care, 2013
As much as 73% of persons living with HIV (PLWH) experience sleep disturbances. It has been more than 10 years since the last study that objectively measured sleep behaviors in persons with HIV. The purpose of this pilot study was to explore sleep quality and rest-activity patterns in PLWH. Eight participants completed a sleep diary and 24hour actigraphy for 1 week. Compared to accepted norms for ''good sleepers,'' sleep diaries described moderate sleep disturbance, and actigraphy revealed severe sleep disturbance. Bedtime was variable from day to day. Analysis of 24-hour rest-activity patterns from actigraphy also indicated disorganization of sleep timing across days. Results of this pilot study suggest that sleep disturbance remains problematic in PLWH despite advancements in the disease management. Pharmacological interventions are effective but generally recommended for short-term use. Behavioral treatments may be useful for longerterm management of sleep patterns in PLWH, but further research is needed.
HIV/AIDS - Research and Palliative Care
Background: In comparison to the general population, persons living with HIV show a higher prevalence of poor quality of sleep, with estimates from 24.1-100% vs in the normal population 10-40%. There are not enough data on the poor quality of sleep among HIV-infected persons in Ethiopia. Methods: Hospital-based cross-sectional study design was conducted among 336 HIVinfected persons in Mettu Karl Referral Hospital. Pittsburgh sleep quality index (PSQI), social phobia inventory (SPIN), changes in sexual functioning questionnaire short-form (CSFQ-14), Fagerstrom test for nicotine dependence (FTND), severity of dependence scale (SDS), and CAGE questionnaire (cut down, annoyed, guilty, eye opener) was used. Data were analyzed by SPSS 20 version. Bivariate and multivariable regressions were computed, and a significance level was declared at a point P-value of <0.05. Results: A total of 336 respondents completed all questionnaires with response rate 98.53%. A total of 192 participants (57.1%) had poor sleep quality. Concerning associated factors; positive for social phobia, sexual dysfunction, living alone, poor antiretroviral (ARV) treatment adherence, and drunken alcohol had a positive association with poor sleep quality. Conclusion: Of the persons living with HIV (PLWH) in Mettu Karl Referral Hospital, 57.1% experienced poor sleep quality. Social phobia, living arrangement, sexual dysfunction, poor ARV treatment adherence, and use of alcohol showed a significant association with poor quality of sleep. The findings suggest that a longitudinal study will be needed to elucidate the causal relationship of variables, and routine screening of poor sleep quality among PLWH is highly recommended. Furthermore, integrating and launching mental health services at ART clinic is greatly important.
Recent Advances in Biology and Medicine, 2017
Human immunodeficiency virus (HIV)-infected individuals have been shown to have a high prevalence of sleep disturbances. Both the effects of the virus and the antiretroviral drugs may cause sleep disturbances. We sought to determine the prevalence and predictors of sleep disorders among HIV seropositive adult subjects presenting at an outpatient hospital setting. One hundred and fifty six subjects were recruited for the study by using a sleep disorder screening questionnaire. The mean ages of the participants were 38.7 6 9.23 and 39.5 6 9.23 for those with and those without sleep disorder, respectively. The prevalence rate of sleep disorders was 46.2%. Elevated systolic blood pressure, lower CD4 count levels, and being on the highly active antiretroviral therapy combination TDF/3TC/ATZ/lpvr were associated with sleep disorders. The high prevalence rate observed necessitates routine screening for sleep disorders among HIV/AIDs patients.
Iranian journal of psychiatry, 2013
Based on Pittsburg Sleep Quality Index, it has been reported that most human immunodeficiency virus (HIV) positive patients suffer from various degrees of sleep problems. Sleep disorders can affect quality of life, physical and social functioning and can also cause chronic fatigue. Some psychological and physiological factors are related to sleep quality. The purpose of the present study was to evaluate sleep quality and its related psychological and physiological factors in Iranian human immunodeficiency virus positive patients who were candidates for initiation of antiretroviral therapy. This was a cross- sectional study of 59 HIV positive out-patients in stages 2 or 3 of HIV disease who were candidates for initiation of antiretroviral therapy. Pittsburg Sleep Quality Index (PSQI), Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS) and Somatization Subscale of Symptom Checklist 90 (SCL-90) were used to assess the patients' sleep quality, depression, ...
2024
Good‑quality sleep is defined by its ability to minimize disturbances, provide adequate duration, and maintain a balanced progression through sleep stages. Sleep disturbance is a common complaint in people living with HIV/AIDS. Despite the influence of sleep disturbance on treatment adherence, quality of life, work productivity, risk of chronic illness. Studies have reported sleep disturbances among HIV/AIDS patients in sub‑Saharan African countries (SSA), yielding varied results at the country level. Therefore, conducting a systematic review and meta‑analysis is essential. This systematic review and meta‑analysis aimed to evaluate the prevalence of poor sleep quality and identify associated factors among HIV/AIDS patients in sub‑Saharan African countries. We systematically searched across various databases, including PubMed, African Journals Online, Scopus, Cochrane Library, HINARI, and Science Direct. Additionally, we conducted searches using Google and Google Scholar search engines. Microsoft Excel was used for data extraction, and the data were analysed using STAT version 17.0. We assessed heterogeneity using Cochran’s Q test and I2 test and checked for small study effects using funnel plot symmetry and Egger’s test. Pooled prevalence and associated factors were estimated using a random‑effects model at a 95% confidence interval (CI) and significance level of p < 0.05. To identify factors associated with poor sleep quality among individuals living with HIV/AIDS, odds ratios (ORs) and their corresponding 95% CI were calculated. This analysis combined data from 15 separate studies involving a total sample size of 5176 participants. The pooled prevalence of poor sleep quality among HIV/AIDS patients in SSA countries was 49.32% (95% CI 41.32–56.8%). Factors significantly associated with poor sleep quality included depression (OR 2.78; 95% CI 1.21–6.40) and CD4 count < 200 cells/mm3 (AOR 3.15; 95% CI 2.41–4.15). In this study the prevalence of poor sleep quality among HIV/AIDS patients in SSA was higher and differs across the countries, ranging from 21.7 to 73.7%. The findings underscore the urgent necessity for programs
AIDS and Behavior, 2013
Quality of Life Research, 2005
and The Mind-Body Research Group (2005). Sleep quality and health-related quality of life in HIV-infected African-American women of childbearing age.
Patient Preference and Adherence, 2013
Sleep disturbances have been reported to be higher in human immunodeficiency virus (HIV)-infected individuals compared to the general population. Despite the consequences of poor quality of sleep (QOS), research regarding sleep disturbances in HIV infection is lacking and many questions regarding correlates of poor QOS, especially in marginalized populations, remain unanswered. We conducted one-on-one qualitative interviews with 14 marginalized HIV-infected individuals who reported poor QOS to examine self-reported correlates of sleep quality and explore the relationship between QOS and antiretroviral adherence. Findings suggest a complex and multidimensional impact of mental health issues, structural factors, and physical conditions on QOS of these individuals. Those reporting poor QOS as a barrier to antiretroviral adherence reported lower adherence due to falling asleep or feeling too tired to take medications in comparison to those who did not express this adherence barrier. These interviews underscore the importance of inquiries into a patient's QOS as an opportunity to discuss topics such as adherence, depression, suicidal ideation, and substance use.
Applied Nursing Research, 2013
Neurology research international, 2014
Aim. To determine the prevalence of sleep disturbance and its associated characteristics in HIV-positive outpatients on HAART using the PSQI. Methods. Using a cross-sectional design, 300 patients attending the outpatient HIV/AIDS clinic at the Lagos State University Teaching Hospital were recruited. Baseline data obtained included the participants' demographic data, educational qualification, and marital status. Their treatment history, including duration since HIV diagnosis, the most recent CD4 cell count, and current antiretroviral therapies, was obtained from their case records. Each participant completed the PSQI questionnaire and those with scores ≥5 were diagnosed with poor sleep quality. Results. The participants were made up of 70.7% females and 29.3% males. Their ages ranged between 18 and 74 years with a mean of 38.9 ± 10.3 years. According to the PSQI, 59.3% reported poor sleep quality. The mean score of those with poor quality sleep (9.2 ± 3.3) was comparable to that...
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