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Anaemia in pregnancy in developing countries

1998, BJOG: An International Journal of Obstetrics and Gynaecology

Abstract

Leeuw NKM de, Lowenstein L, Hsieh YS. Iron deficiency anaemia and hydremia in normal pregnancy. Medicine (Baltimore) 1966; 45: Johnson-Spear MA, Yip R. Hemoglobin difference between black and white women with comparable iron status: justification for race-specific anaemia criteria. Am J Clin Nutr 1994; 60: 1 17-12 1. Baker SJ, DeMaeyer EM. Nutritional anemia: its understanding and control with special reference to the work of the World Health Organization. Am JClin Nutr 1979; 32: 368-417. Murphy JF, O'Riordan JO, Newcombe RG, Coles EC, Pearson JF. Relation of Haemoglobin levels in first and second trimesters to outcome of pregnancy. Lancet 1986; 1 : 992-994. 291-3 15. 0 RCOG 1998 Br J Obstet Gynaecol 105, 385-391

Key takeaways

  • Anaemia in pregnancy is a very common problem in most developing countries.
  • In developing countries anaemia and iron deficiency are likely to result in higher perinatal and infant mortality and morbidity.
  • In regions where iron deficiency is an important cause of anaemia the benefits of oral iron treatment probably outweigh the risks.
  • Anaemia associated with vitamin A deficiency has been reported6* and vitamin A supplementation together with iron has led to improved haemoglobin levels in a number of s t u d i e~~~.~~.
  • Inflammatory conditions may be a source of error in diagnosing iron deficiency anaemia, as for example, serum ferritin, which is most commonly used to define iron deficiency, is raised in inflammation.