Ventricular septal defect

Heart, 1983

Clinical and haemodynamic findings were reviewed in 109 consecutive patients in whom an isolated ventricular septal defect was diagnosed after the age of 15 years (range 15-65 years). Most patients had no or minor cardiac symptoms. Based on the left to right shunt size and pulmonary pressure, 32 (29%) patients had large and 75 (69%) small ventricular septal defects, whereas in two (2%) patients data were insufficiently complete for determining the size. The anatomical location was membranous in 92% and muscular in 8% of the 51 patients in whom this could be assessed from a left ventricular angiogram or the surgeon's report of a subsequent operation, or both. Nine (8%) patients had developed the Eisenmenger syndrome, 12 had aortic regurgitation, and 16 (15%) had bacterial endocarditis, the incidence of the latter being 5*7 per 1000 patient years. Of the 34 (31%) patients who underwent surgery, five (15%) died while in hospital.

Archives of disease in childhood, 2016

Ventricular septal defects (VSDs) are the most common congenital heart defects (CHDs). Previous studies indicate an increased risk of endocarditis, aortic regurgitation, left ventricular outflow tract obstructions, pulmonary hypertension, arrhythmias and sudden death in patients with isolated VSDs. The present nationwide cohort study reports mortality and cardiac complications requiring hospitalisation or intervention in children with isolated VSDs. Medical information concerning all 943 871 live births in Norway in 1994-2009 was retrieved from the Medical Birth Registry of Norway, the Cardiovascular Disease in Norway project, the Oslo University Hospital's Clinical Registry of Congenital Heart Defects and the Norwegian Cause of Death Registry. Isolated VSDs were identified in 3495 children without known chromosomal aberrations or extracardiac malformations. Surgical or catheter-based treatment of VSD was performed in 181 (5.2%) cases. Twelve (0.3%) children with VSDs died befor...

Zenodo (CERN European Organization for Nuclear Research), 2021

Background: Ventricular septal defects (VSDs) are still one of the most prevalent surgical indications in newborns and children with congenital heart disease. With advances in echocardiography, cardiac catheterization is no longer necessary in the treatment of these individuals. Although perioperative mortality and morbidity for isolated defects are still low, unique scenarios such as surgical care of numerous VSDs and decision-making in patients with pulmonary hypertension remain difficult. This chapter examines both classic and recent evidence that has shaped the management of this condition, as well as the facts underlying developing interventional methods utilized in both the catheterization lab and the operating room. Conclusion: VSD is the most common congenital abnormality at birth. Small flaws should close on their own within the first year of life; however, larger faults can cause serious difficulties. The major interventions for big problems are surgical VSD closure and device closure.

The American Journal of Cardiology, 1965

Thirty-six infants were born in the Bronx Municipal Hospital Center or Lincoln Hospital (local group). These patients were unselected, in that the decision to catheterize them was based only on the clinical diagnosis of a ventricular septal defect and not on an assessment of its size ...

Cardiovascular diseases, 1975

European Journal of Cardio-Thoracic Surgery, 2003

JPMA. The Journal of the Pakistan Medical Association, 2011

To determine the frequency of various types of ventricular septal defects (VSD) and associated complications in local paediatric population. A cross sectional descriptive study was conducted on children undergoing echocardiography in a single centre from January 2006 to December 2009 at Paediatric Cardiology Department, Ch. Pervaiz Elahi Institute of Cardiology Multan- Tertiary referral centre for paediatric and adult cardiac services in South Punjab. The data on all children below 15 years of age undergoing detailed transthoracic two-dimensional echo and Doppler studies was reviewed. Cases with isolated ventricular septal defects were studied for age of presentation, gender, type, and associated complications. The data was analyzed with SPSS 11 version. A total of 5018 patients with congenital heart diseases underwent echocardiography during this period. A total of 1276 patients had isolated VSD (25%). Mean age was 3.1 +/- 3.64 years (range: 1 day to 15 years). Females were 440 (34...

Journal of Evolution of Medical and Dental Sciences

BACKGROUND Ventricular Septal Defect (VSD) is the most common congenital heart disease in children. Our study was done with the aim to analyse the clinical profile and size and type of VSD in Paediatric patients admitted in a tertiary care hospital in Assam. METHOD This is a prospective cross-sectional study of 2 years' duration conducted in the Department of Paediatrics, Assam Medical College, Dibrugarh. Children aged 1 month to 12 years with a clinical diagnosis of VSD were evaluated by echocardiography to confirm the diagnosis. Only isolated VSD cases were enrolled in the study. Data was entered and analysed by SPSS version 16. RESULT Among the total of 70 cases, 47.1% were female and 52.9% were male; 54.3 % cases presented in infancy and 46 patients (65.7%) had their first symptom before one year. Perimembranous was the commonest (74.3%) followed by muscular (22.9%) and doubly committed subarterial (2.9%) VSD. Common symptoms were cough (68.6%), fever (68.6%), breathlessness (52.9%), feeding problem (45.7%), failure to thrive (45.7%) and fatigue (40%). Pansystolic murmur (100%), tachypnoea (62.9%), tachycardia (62.9%), crepitations (57.1%), subcostal retraction (45.7%), hepatomegaly (34.3%) and wheeze (20%) were the frequent clinical findings. Complications associated were pneumonia (57.1%), malnutrition (51.4%), congestive cardiac failure (CCF) (34.3%) and pulmonary hypertension (17.1%). CONCLUSION Perimembranous was the commonest type of VSD. Small VSD presented with mild symptoms or were asymptomatic. Moderate and large VSD presented with severe symptoms and complications. Clinical examination and diagnostic modalities like chest X-ray, ECG and echocardiography is helpful in diagnosing VSD. Early diagnosis and management will help in preventing the associated complications, thereby reducing the mortality and morbidity in these children.

Journal of the American College of Cardiology, 2002

2020

Cite as: Monzón Castillo EP, Tejada Martínez G. Isolated ventricular septal defect. A case report. Rev Peru Ginecol Obstet. 2020;66(3). DOI: https://doi.org/10.31403/rpgo. v66i2267 ABSTRACT Congenital heart disease is the most common congenital anomaly. Ventricular septal defect (VSD) is a frequent congenital heart disease in newborns, affecting 25 to 30% neonates with cardiac defects. Muscular VSDs are more frequent than perimembranous VSDs. The association of cases with chromosomal anomalies and isolated VSD is relatively low. Spontaneous closure of isolated VSD is higher with small VSD cases, and the muscular VSD is more likely to close spontaneously than the membranous or perimembranous types. Therefore, diagnosis of isolated muscular VSD with no other anomalies can be considered a benign finding.