ANALYSIS OF PHYTOCHEMICALS AND MIMOSINE FROM MIMOSA PUDICA

2015

Chemical diversity in natural product is an immensely rich source of new pharmaceuticals, cosmetics, agrochemicals and other economically important chemicals. Therapeutic potentials of herbal drug ranges from parts of plants, through simple extracts to isolated active constituents. Phytochemical evaluation compresses of different chemical tests and chemical assay. The isolation, purification and identification of active constituents are chemical methods of evaluation. The phytochemical evaluation also covers phytochemical screening carried out for establishing chemical profile of crude drug. The purity of crude drugs is ascertained by quantitative estimation of active chemical constituents present in them. The method may be useful in determining single active constituents or the group of related constituents present in the same drug. The spectrophotometric analysis using UV/ visible/ IR/ Fluorescence/ NMR/ Mass/ X-ray diffraction are physical methods of assay. The modern techniques ...

2013

Objective: To evaluate the anti-nociceptive, acute toxicity, gastro intestinal motility, anti-pyretic investigations of leaf extract of Mimosa pudica L. leaves in Swiss albino mice following oral administration. Methods: In-vivo anti-nociceptive activity test was evaluated by tail immersion test. In-vivo acute toxicity test was conducted using acute toxic class method. In-vivo gastrointestinal motility was determined by charcoal feces defecation time. In-vivo antipyretic activity test was evaluated by brewer’s yeast induced pyrexia. Results: In-vivo anti-nociceptive activity test shows that methanol & ethanol extracts (250 & 500 mg/kg b.w.) performed significant activity (p<0.05) in mice comparing to the standard drug diclofenac Na. In-vivo acute toxicity test was done on mice with methanol, ethanol and chloroform extracts (2000, 1000, 500 mg/kg b.w.) of Mimosa pudica leaf and no reaction or death occurred in mice during two weeks of observation. In-vivo gastrointestinal motility...

International Research Journal of Modernization in Engineering Technology and Science, 2024

Mimosa pudica Linn., also known as the "touch-me-not" plant, is a creeping perennial herb recognized for its fast leaf-folding response to touch. This review examines the botanical, phytochemical, pharmacological, and therapeutic properties of M. pudica. The plant contains numerous bioactive chemicals, including alkaloids, flavonoids, tannins, saponins, and glycosides, which contribute to its diverse therapeutic qualities. Traditionally, it was used to heal wounds, skin problems, diarrhea, and inflammation. Recent pharmacological research have shown that it has antioxidant, antibacterial, anti-inflammatory, analgesic, antidiabetic, and hepatoprotective properties. Its distinct thigmonastic response has piqued attention in plant physiology and environmental adaptation research.

Objective: To evaluate the anti-nociceptive, acute toxicity, gastro intestinal motility, anti-pyretic investigations of leaf extract of Mimosa pudica L. leaves in Swiss albino mice following oral administration. Methods: In-vivo anti-nociceptive activity test was evaluated by tail immersion test. In-vivo acute toxicity test was conducted using acute toxic class method. In-vivo gastrointestinal motility was determined by charcoal feces defecation time. In-vivo antipyretic activity test was evaluated by brewer’s yeast induced pyrexia. Results: In-vivo anti-nociceptive activity test shows that methanol & ethanol extracts (250 & 500 mg/kg b.w.) performed significant activity (p<0.05) in mice comparing to the standard drug diclofenac Na. In-vivo acute toxicity test was done on mice with methanol, ethanol and chloroform extracts (2000, 1000, 500 mg/kg b.w.) of Mimosa pudica leaf and no reaction or death occurred in mice during two weeks of observation. In-vivo gastrointestinal motility test indicates significant (p<0.01) increase in gastrointestinal motility by ethanol extracts of (250 & 500 mg/kg b.w.) comparing to the standard drug loperamide. In-vivo antipyretic activity test shows that methanol (250 & 500 mg/kg b.w.), ethanol (250 & 500 mg/kg b.w.) and chloroform (250mg/kg b.w.) extracts showed significant (p<0.05) reduction in temperature of mice comparing to the standard drug paracetamol. Conclusion: The result of the study indicates analgesic, antipyretic properties along with gastrointestinal motility stimulating effects. According to the acute toxicity study, the leaf extracts are safe up to 2000 mg/kg in-vivo concentration.

2010

The roots of Mimosa pudica Linn (Mimosae) are reported to have great medicinal value. Pharmacognostic evaluation including examinations of morphological and microscopic characters, ash value, powder analysis, and extractive values were carried out. Phytochemical screening including qualitative chemical examinations was also carried out.

International Journal of Scientific Research in Science and Technology, 2019

In the developing world the trend has been changed from synthetic to natural medicine. Trees and plants are sources of many medicines. The use of medicinal plants was compiled in Ayurveda which listed more than 8000 herbal remedies. Mimosa rubicaulis Lam belonging to the family Fabaceae and subfamily Mimosoideae. It is bipinnately compound, each leaf having 8–12 pairs of pinnae, each with 16–20 pairs of pinnules, unlike this plant is having good potential activity in plant due to it has been attributed to their flavanoid and sterol contents. Several flavanoids isolated from these plants have been discovered to possess significant Various Pharmacological activity. Literature review reports the presence of flavanoids, triterpenoids, phytosterols and alkaloids in Mimosa rubicaulis Lam.

Stamford Journal of …, 2009

The petroleum ether, chloroform and methanol crude extracts of the two different plant parts (aerial part and root) of Mimosa pudica (Mimosaceae) were screened in vitro for cytotoxicity studies by brine shrimp lethality bioassay and antimicrobial screening by disc diffusion ...

International Journal of Molecular Sciences, 2021

The Mimosa genus belongs to the Fabaceae family of legumes and consists of about 400 species distributed all over the world. The growth forms of plants belonging to the Mimosa genus range from herbs to trees. Several species of this genus play important roles in folk medicine. In this review, we aimed to present the current knowledge of the ethnogeographical distribution, ethnotraditional uses, nutritional values, pharmaceutical potential, and toxicity of the genus Mimosa to facilitate the exploitation of its therapeutic potential for the treatment of human ailments. The present paper consists of a systematic overview of the scientific literature relating to the genus Mimosa published between 1931 and 2020, which was achieved by consulting various databases (Science Direct, Francis and Taylor, Scopus, Google Scholar, PubMed, SciELO, Web of Science, SciFinder, Wiley, Springer, Google, The Plant Database). More than 160 research articles were included in this review regarding the Mimo...

2015

The present study aims to screen pharmacological and phytochemical screenings of the Mimosa diplotricha . For this the ethanolic crude extract of M. diplotricha (EMd) was undergone for checking antioxidant, anti-inflammatory and membrane stabilizing, anti-diarrheal and clotlysis activities followed by a preliminary phytochemical screening. Results suggest that, the EMd concentration-dependently exhibited antiradical (DPPH: 1,1-diphenyl-2-picrylhydrazyl) and anti-inflammatory activities. The EMd also exhibited promising anti-diarrheal effect in Swiss mice, while a negligible clotlysis activity was observed in clotted human blood. Additionally, the phytochemical screening of the crude plant extract revealed the presence of alkaloids, glycosides, flavonoids and reducing sugars. In conclusion, M. diplotricha may be a good source of antioxidant and anti-diarrheal agents. Further researches are recommended for the isolation and characterization of its phytochemicals.

2019

To cure all aliments of human being mother nature provides a complete store house of remedies since past years. In legume family Mimosa is one of the largest genera which distribute more than 500 species. Mimosa pudica (Family: Mimosaceae) is used as an ornamental plant due to its thigmonastic and nyctinastic movements. The plant is rich source of flavonoids, plant hormones, glycosides, amino acid, tannin etc. It folds itself when touched and sreads its leaves once again after a while. It majorly possesses antibacterial, antivenom, antifertility, anticonvulsant, antidepressant and various other pharmacological activities. The herb has been used traditionally for ages in the treatment of urogenital disorder, piles, dysentery, sinus and also applied on wounds. It is the most important plant origin has tremendous future for research.