Bağlama metodu 1 - Yaşar Kemal alim/M. Aydın Atalay

Availing medium water swelling hydrogel would significantly contribute to the production of soil conditioner and conductive gels. In the present work, hydrogel was prepared based on corn and potato starches, acrylonitrile (AN) as a grafting monomer and H 2 O 2 /Fe 2+ redox system as a source of free radicals. The parameters tested for the preparation were (AN) / starch ratio of 0.3 to 1.6, H 2 O 2 dose of 0.03 to 0.21 of starch weight and liquor to solid ratio o f 10 to 30. The best conditions for grafting efficiency were obtained at :AN/starch ratio of about 1 .4 for corn and potato starches, H 2 O 2 dose of about 12% and 15% of starch weight for corn and potato starches, respectively and liquor to solid ratio of 1:10. The prepared hydrogel at optimum attained conditions was tested for water swelling under different operating conditions. An empirical correlation for hydrogel water retention (WR) was deduced as a function of pH, temperature (T o C), electric conductivity (C, as µmho /cm) and time (t, hr) as follows: WR = [21.5C -0.21 -1.2pH + 0.44T] (t 0.3 ).

Buku karya cendekiawan kelahiran Mau, India ini bisa dikatakan sebagai sebuah karya yang monumental. Suatu kerja ilmiah yang dibangun tanpa emosional, mengundang pihak mana pun untuk mengkaji buku ini pada saat serangan terhadap Al-Qur'an menjadi sesuatu yang umum.

Buku karya cendekiawan kelahiran Mau, India ini bisa dikatakan sebagai sebuah karya yang monumental. Suatu kerja ilmiah yang dibangun tanpa emosional, mengundang pihak mana pun untuk mengkaji buku ini pada saat serangan terhadap Al-Qur'an menjadi sesuatu yang umum.

Segala tentang zakat

Journal of Research in Nursing, 2016

The aim of this study was to develop delirium care pathways (DCPs) useable and relevant for registered practitioners in all care settings: community; acute; and nursing homes. A qualitative approach was adopted to develop the pathways inductively. Focus groups and one-to-one interviews with registered practitioners (n = 45) working as managers, practitioners and clinical nurse consultants were undertaken to develop draft versions of the pathways, which was pilot trialled across 19 clinical settings. The publication of the DCPs was a concise and easily readable document for registered practitioners who required immediate guidance on how to implement evidence-based delirium care for older people and their family carers, including three patient journeys explaining best-practice delirium care in community, acute and nursing home care settings, a webpage resource and printable posters of the pathways' patient journeys to promote the use of the pathways in clinical settings. The work undertaken to develop the pathways was further developed through new policy documents, state-wide initiatives to improve delirium care in hospitals, development of educational resources on delirium care and other knowledge translation projects on this topic.

2018

The pharmaceutical industry continues to be plagued by data integration and management challenges across the clinical trial data life cycle. Considerable progress has been made in recent years with the implementation of CDISC standards. Historically, standards focused on distinct segments of the clinical trial process: study design, submission, publication. To provide a futureproof solution, these standards must be adapted and integrated holistically and consistently across all use cases. Linked Data provides a potential solution by representing clinical trial concepts at their atomic level, then leveraging ontological classification and rules integration. This paper reports results from the PhUSE project "Clinical Trials Data as RDF." SDTM data was converted to Linked Data based on CDISC and custom ontologies, then reassembled into high-quality, submission-ready data sets. The approach has several advantages, including the inextricable representation of data and their mea...

JCO Clinical Cancer Informatics

PURPOSE Because of expanding interoperability requirements, structured patient data are increasingly available in electronic health records. Many oncology data elements (eg, staging, biomarkers, documentation of adverse events and cancer outcomes) remain challenging. The Minimal Common Oncology Data Elements (mCODE) project is a consensus data standard created to facilitate transmission of data of patients with cancer. METHODS In 2018, mCODE was developed through a work group convened by ASCO, including oncologists, informaticians, researchers, and experts in terminologies and standards. The mCODE specification is organized by 6 high-level domains: patient, laboratory/vital, disease, genomics, treatment, and outcome. In total, 23 mCODE profiles are composed of 90 data elements. RESULTS A conceptual model was published for public comment in January 2019 and, after additional refinement, the first public version of the mCODE (version 0.9.1) Fast Healthcare Interoperability Resources (...

Neuropsychology

Objective: We aimed to develop a measure to specifically assess the functioning of the perirhinal cortex (PRC), a brain structure affected very early in Alzheimer's disease (AD) pathology. In this novel task, participants were shown arrays of six complex figures and had to identify the "odd-one." Method: The pilot study included 50 normal controls (NCs) and 50 patients in very early stages of AD. Participants completed the task and received MRI scanning. Best differentiating items were determined and applied in a validation study including 25 NCs, 27 early-stage AD patients, and 26 patients with major depression. Logistic regression models investigated if task performance predicted group membership. Task performance was then related to whole-brain gray matter integrity. As proof of concept, cortical thickness values of four regions of interest (ROIs; e.g., medial PRC and entorhinal cortex [ERC]) were compared between the groups. The associations of task performance and cortical thickness of the ROIs were investigated using linear models. Results: Task performance showed good discriminative ability between early-stage AD patients and NCs. Whole-brain analyses revealed four significant clusters (p < .001) with peak voxels in parahippocampal regions including PRC and ERC. ROI analyses showed distinctly reduced cortical thickness in the AD group compared to both other groups in the medial PRC and ERC (p ≤ .001). Task performance modeled by ROI cortical thickness did not achieve significant results. Conclusion: Although further validation is needed, especially with age-matched participant groups, these findings indicate that the task detects early cognitive impairment related to AD.

Medical Writing, 2020

Clear communication with the public and with potential clinical trial participants and their caregivers is foundational to the ethical tenets of respect, justice, and beneficence. However, health literacy, even of highly educated individuals, often declines when presented with complex content in unfamiliar contexts and in times of stress, all of which are characteristic of the types of situations people find themselves in when considering and participating in a research study. Here we describe an initiative to pilot the development of a cross-organisational plain language clinical research glossary to promote clarity, consistency, and transparency. The goal is to develop a common resource that can be used across clinical research stakeholder groups to increase understanding of clinical research and empower sound individual decision making.