Unusual presentation of a giant glomus tumor

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2015

Introduction Glomus tumor is a neuromyoarterial tumor. It is a rare tumor which accounts for about 2% of all hand tumors. The diagnosis is based on the triad of symptoms, clinical examination which includes three tests, magnetic resonance imaging, and ultrasound imaging. The most common treatment is surgical excision, using transungual or lateral subperiosteal approach. Sclerotherapy and radiotherapy may be the treatments of choice, but they are less effective. The recurrence rate is high -from 5% to 50%. Case Outline We diagnosed a glomus tumor of 1 cm in diameter in the distal phalanx of the fourth finger of the right hand in a 30-year-old woman. She had been visiting different physicians for more than two years and had been variously diagnosed. We performed a biopsy of the tumor, which was bleeding profusely during the procedure. Upon biopsy results, the tumor was excised with transungual approach. Two and a half months after the procedure the patient was feeling well. Conclusion There should be higher awareness of this tumor in order to diagnose it more easily and treat it accordingly, and thus alleviate the severe pain which the tumor causes. When it is considered as the possible cause of the lesion, the diagnosing is easier and treatment is immediate.

Journal of Taibah University Medical Sciences, 2016

Journal of Neurological Surgery Reports, 2015

Hearing loss, headache, tinnitus, and subcutaneous masses are the most commonly reported symptoms in GCTs of the skull base. 7,8 Findings on examination are minimal including micro-otoscopy because these tumors originate in the deeper structures of the temporal/sphenoid bone. Facial nerve and lower cranial nerve involvement has been observed in advanced stages of the disease; pain is an

Paragangliomas are also called glomus tumors, a rare, neuroendocrine neoplasm that arises from the paraganglia in the glomus cells derived from the embryo in the neural crest of the sympathetic nervous system (a branch of the autonomic nervous system). This case report is on glomus tympanicum on the right side in a 36-year-old male presented with pulsatile tinnitus and ear pain. On otoscopic examination and radiological findings, it appears as a reddish mass behind the tympanic membrane. The pre-operative and the post-operative audiological findings are profiled and discussed.

Journal of Neurological Surgery Part B: Skull Base

Glomus tumors, also called paragangliomas, are challenging lesions, demanding accurate knowledge of complex anatomy and pertinent approaches. We present the case of a 39-year-old male presenting with headache, vertigo, tinnitus, hearing loss, and hoarseness. Neurological assessment showed facial paralysis House–Brackmann IV and lower cranial nerves deficits. Preoperative magnetic resonance imaging (MRI) demonstrated two large lesions, suggestive of a glomus jugulare, and carotid body paragangliomas. Considering worsening of the symptoms and the important mass effect of both lesions over the neurovascular structures, microsurgical excision was offered, after preoperative tumor embolization. We preferred to approach both lesions in the same operation, starting by the cervical tumor. Initially there was not an easily identifiable dissection plane between the tumor and the carotid artery, but it was achieved after performing a subadventitial dissection, being possible to resect the enti...

American Journal of Clinical Pathology, 2014

Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. The usual locations for glomus tumors are the digits, where the glomus bodies are normally present. They have been reported in extradigital sites, including bone, lung, intestinal tract, and breast. In the inguinal region, it is rarely reported and one patient with multiple (four) glomus tumors of inguinal region has been described by Antonio et al in 2002. We report a case of a 53-year-old man who presented with left lower limb pain and was found to have an enlarged left inguinal soft tissue mass mimicking a lymph node on venous duplex scan. He underwent an excisional biopsy and revealed a 1.2-cm soft tissue mass in the left inguinal region that was sent for histological diagnosis. Microscopic examination showed benign proliferation of small capillaries and blood vessels with nests of round uniform cellspericytes-glomocytes without evidence of malignancy or atypia. Immunohistochemical studies showed tumor cells positive for alpha smooth muscle actin and negative for CD 34 confirming the diagnosis of a glomus tumor. Schiefer et al described a 20-year experience of fifty six (56) extra digital glomus tumors in a single institution, and none was described in the inguinal region. This report widens the spectrum of the differential diagnoses for masses in inguinal region. Because of their rarity, there are no clear guidelines for follow-up of glomus tumors, but accurate diagnosis and understanding of usually benign behavior, are crucial for the management.

The Journal of Laryngology & Otology, 1995

Haemangiopericytoma and glomus tumours are infrequent neoplasms in otorrhinolaryngology. A case of glomus tumour with haemangiopericytomatous features of the left amygdalar fossa tsaeported. Its clinical, surgical and histological features are described. This case report supports the unitary concept of smooth muscle tumours of the small vascular wall.

Hand and Microsurgery, 2016

Aim: Glomus tumors are typically located in the subungual region in 75%-90% of patients. However, these tumors can be seen in atypical localizations which are extra-digital parts of the human body. Here, we present the management of a series of five patients with extra-digital glomus tumors treated surgically. Patients and methods: The mean age of the patients was 40.6 years. The mean duration between symptom onset and presentation was 3.6 years. The localization of the tumors were anterolaterally of the thigh, posteriorly of the humerus lateral condyle, posteriorly of the humerus supracondylar region, anteromedially of the tuberositas tibia, and on the dorsal side of the wrist. Results: The mean follow-up was at 52.8 months. For all patients, all lesions healed without any wound issues and no recurrences were noted during the follow-up period. Conclusion: When a painful mass is found in the body, glomus tumors should be kept in mind. The consideration of symptoms, including pain, temperature sensitivity, point tenderness, and discoloration, common characteristics of glomus tumors, may aid diagnosis.

Journal of Shoulder and Elbow Surgery, 2009

Glomus tumors are a tumor of perivascular, temperatureregulating bodies; 75% occur in the hand, 50% of these are subungual, and 50% occur with erosion of the distal phalanges. They are typically less than 1 cm in diameter. The tumor may often present as a small, bluish-red nodule. Nail ridging is a common finding. Magnetic resonance imaging (MRI) is helpful in making the diagnosis. Treatment is marginal excision.

2011

Glomus tumours (GT), neoplasms of the glomus body comprise 4.5% of upper limb tumours. Seventy-five per cent of these occur in the hand, and most are subungual (50%). We performed a literature review and retrospective search of histopathologically confirmed GT seen from 1995 to 2009. Fifteen patients were identified, with an average age of 49.6 years. Eight were in the hand, 2 in the upper limb, 2 lower limb and 3 in the ear. Eighty-six per cent presented with pain and 50% underwent radiological investigation. Most diagnoses followed biopsy findings. Surgical excision resulted in a recurrence rate of 13%. The average time to diagnosis was 3.3 years. The average duration of symptoms was 7 to 11 years with an average of 2 to 3 consultations prediagnosis. MRI remains the most useful imaging modality (82 to 90% sensitivity). Excision biopsy is the most common treatment. Greater awareness is needed for quicker diagnosis.