Skin lesions in chronic renal dialysis
Luis Alberto Peres2014, Jornal Brasileiro de Nefrologia
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Abstract
Cutaneous and mucosal disorders are the most common problems in patients on long-term hemodialysis. The dialysis prolongs the life expectancy, giving time of these changes to manifest. The aim of this study was to evaluate the prevalence of dermatologic problems among patients with chronic renal disease (CRD) undergoing hemodialysis. Methods: One hundred forty-five patients with chronic renal disease undergoing hemodialysis were studied. All patients were thoroughly examined for skin changes, hair, nails and mucous membranes by a single examiner and laboratory tests were assessed. The data were stored in a database Microsoft Excel and analyzed using descriptive statistics. The continuous variables were compared using Student's t-test and categorical variables the chi-square test or Fisher's Exact test. Results: The study included 145 patients, mean age of 53.6 ± 14.7 years, predominantly male (64.1%) and caucasian (90.0%). The average time of dialysis was 43.3 ± 42.3 months. The main underlying diseases were: hypertension in 33.8%, diabetes mellitus in 29.6% and chronic glomerulonephritis in 13.1% of the patients. The main dermatologic manifestations observed were: xerosis in 109 (75.2%), ecchymosis in 87 (60.0%), pruritus in 78 (53.8%) and lentigo in 33 (22.8%) patients. Conclusion: Our study showed the presence of more than one alteration per patient. Cutaneous alterations are frequent in patients on dialysis. Further studies are needed to better characterization and management of these dermatosis.
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IOSR Journals , 2019
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Cutaneous Alterations in Patients With Chronic Renal Failure
International Journal of Dermatology, 1992
The purpose of this study was to evaluate the prevalence of dermatologic problems among patients witb chronic renal failure (CRF) undergoing hemodialysis or peritoneal dialysis. One-hundred and two patients witb CRF were examined for the presence of cutaneous alterations. All patients examined bad at least one cutaneous lesion. Tbe most prevalent findings were alterations in the cutaneous pigmentation. Of particular interest was an increased prevalence of hyperpigmented macules on the palms and soles. Otber manifestations, seen particularly in the hemodialysis group, included the balf-and-balf nail, pruritus, and keratotic pits of tbe palms and soles. Infectious processes were more prevalent in tbe group undergoing peritoneal dialysis. This study sbowed tbat all patients witb CRF have some type of cutaneous alteration and that the type of dialysis could have some influence upon the incidence of tbese changes.
Cutaneous manifestations in patients with chronic renal failure on hemodialysis
Indian Journal of Dermatology, Venereology and Leprology, 2006
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Cutaneous changes in chronic kidney disease patients on maintenance hemodialysis visiting at tertiary care hospital, Karachi
Journal of Pakistan Association of Dermatologists 2014;24 (2):156-159, 2014
Objective To determine the frequency of cutaneous changes in patients with chronic kidney disease on maintenance hemodialysis. Methods A cross-sectional study conducted A total of 100 patients with chronic kidney disease on maintenance hemodialysis were included. After taking demographic data, cutaneous changes were noted. Mean and standard deviation were computed for quantitative variables (age) and frequency and percentage were computed for categorical variable (sex, cutaneous changes). Results Mean age was 52.58±13.84 years and out of 100 patients 56% were males. At least one skin change was noted in 91%. Among type of manifestations, xerosis was noted in 96%, generalized xerosis 70%, alopecia 70%, half-and-half nails 36%, scaling 20% and ichthyosis 10%. Pruritus was found in 64%, out of these 93% had mild to moderate intensity and 7% had severe intensity of pruritus. Conclusion Chronic kidney disease is associated with a complex array of cutaneous manifestations caused either by the disease or by treatment. Xerosis and pruritus were most common among patients with CKD, so early recognition of cutaneous signs can relieve suffering and decrease morbidity.
" Cutaneous manifestations in chronic renal failure patients on haemodialysis "
Introduction: Chronic renal failure presents with wide range of cutaneous manifestations. Many newer changes have been described since the advent of haemodialysis which prolongs the life expectancy giving time for these changes to manifest. Aims & Objectives: To find the array of various dermatological conditions that can occur in patients of CRF on haemodialysis. Materials and Methods: A total 100 patients with chronic renal failure on haemodialysis and having at least single cutaneous manifestation was included in the study. Results: Of the total 82% of the patients complained of certain skin problems however on examination all patients had at least one skin problem attributable to chronic renal failure. The most prevalent finding among them was Xerosis (52%), Pruritus (32%), Diffuse cutaneous hyperpigmentation (22%), Kyrle's disease (71%) of the total of acquired reactive perforating dermatosis(7%), Fungal infections (16%), Bacterial infections (10%) and Viral in (10%), Purpura (3%) and other Dermatosis (13%).The nail changes observed were Half and Half nails (20%), Koilonychia (18%), Onychomycosis (15%), Sub-ungual hyperkeratosis (8%), Beaus lines (2%) .Hair changes were sparse body hair (10%), dry lustreless hair (4%), and sparse scalp hair (10%). Oral changes observed were Ulcerative stomatitis (29%), Angular chelitis (12%. Other manifestations of CRF observed were like gynaecomastia, psuedokaposis sarcoma, and nephrogenic fibrosing dermopathy. Conclusion: CRF is associated with a complex array of cutaneous manifestations caused either by the disease or by the treatment. The early recognition of cutaneous signs can relieve suffering and decrease morbidity.
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