Dermoscopy of idiopathic facial aseptic granuloma

Idiopathic facial aseptic granuloma is a chronic, benign, and painless facial nodule occurring exclusively in childhood. A case of idiopathic facial aseptic granuloma located on the right cheek of a 2.3-year old boy is described. Repeated assessment of the skin, using a skin pressurization method, revealed no Demodex spp. parasites. Good progress was made after a long treatment with 1% metronidazole cream.

Pediatric Dermatology, 1989

Boletín Médico del Hospital Infantil de México (English Edition), 2020

Background: Rosacea is a chronic inflammatory skin condition that usually occurs in adults and rarely has been reported in children, although both subtypes share the same clinical characteristics. Case report: A 10-year-old female presented dermostosis on the face, affecting cheeks and nose, characterized by erythema, papules, pustules, scars of two years of evolution, as well as bilateral conjunctivitis, blepharitis and corneal opacity. She referred recurrent exacerbations and partial remission of cutaneous lesions and ocular symptoms related to sun exposure. She responded dramatically to systemic and topical antibiotics. Conclusions: Childhood rosacea should be distinguished from other most common erythematous facial disorders, such as acne, granulomatous perioral dermatitis, and sarcoidosis. The distribution of papulopustular facial lesions together with the presence of telangiectasia, flushing and the ocular findings allow the differentiation of rosacea from other facial eruptions.

Anais Brasileiros de Dermatologia, 2013

The granuloma faciale is a rare and benign skin disease of unknown etiology, characterized by chronic leukocitoclastic vasculitis. It is characterized by skin lesions predominantly facial whose course is chronic and slowly progressive. The diagnosis is based on clinical features, histopathology and, more recently, in dermoscopy. We describe the case of a male patient, 40 years old, with a sarcoid lesion on the malar site, whose histopathological examination revealed a mixed inflammatory infiltrate with presence of Grenz zone. Dermoscopy revealed a pink background with white striations. The definitive diagnosis is made by histopathologic evaluation, and dermatoscopy can be helpful. It is known to be resistant to therapy, oral medications, intralesional and surgical procedures are options.

Journal of the American Academy of Dermatology, 1991

17. Van Erp PEl, Rijzewijk 11, Boezeman JBM, et a1. Flow cytometric analysis of epidermal subpopulations from normal and psoriatic skin using monoclonal antibodies against intermediate filaments. Am J PathoI1989;135:865-70. 18. De Mare S, van Erp PEJ, Ramaekers FCS, et a1. Flow cy-Journal of the American Academy of Dermatology tometric quantification of human epidermal cells expressing keratin 16 in vivo after standardized trauma. Arch

British Journal of Dermatology, 2001

ranuloma faciale (GF) is an uncommon chronic and inflammatory dermatosis accepted as a localized form of smallvessel vasculitis with frequent leukocytoclasis. 3,4 Clinically it is characterized by single or multiple asymptomatic, reddish brown to violaceous papules, nodules, and plaques typically localized on the face. The sites of predilection are the sides and tip of the nose, the preauricular area, the cheeks, the forehead, and the helix of the ear. 1,3-7 The condition most commonly occurs in middle-aged, white men, 1,3-7 and is limited to the skin, without any systemic manifestations. The course is generally chronic and asymptomatic with frequent resistance to the therapy. Extrafacial lesions of GF are rather infrequent. 3-11 The facial lesions usually precede extrafacial lesions, which may present months to several years after the appearance of facial disease. Occasionally, extrafacial lesions may appear simultaneously or exceptionally they may occur alone. 8,9 Researchers have suggested that factors such as actinic exposure or a localized Arthus-like response might play a pivotal role in triggering the lesions. 3,4,12 Some

Our Dermatology Online, 2022

Anais Brasileiros de Dermatologia, 2018

Granuloma faciale is a rare, chronic dermatologic disorder, which mainly affects the face. Recently, dermoscopy has been demonstrated as an important ancillary tool on the clinical diagnosis of facial dermatoses. We report two cases of granuloma faciale with yellow areas on dermoscopy that was not yet described in the literature, corresponding to abundant hemosiderin on histopathological examination.

Indian Journal of Dermatology, Venereology and Leprology, 2007

British Journal of Dermatology, 1997

Journal of the European Academy of Dermatology and Venereology, 2014

Background Several common inflammatory dermatoses, such as rosacea, seborrheic dermatitis (SD), discoid lupus erythematosus (DLE) and granulomatous skin diseases manifest as erythematous macules or plaques on the facial skin.

Serbian Journal of Dermatology and Venerology, 2010

Granulomatous rosacea is considered to be the only true variant of rosacea. Diascopy of larger lesions often reveals apple-jelly nodules, indicating their granulomatous histology. Other signs and symptoms of rosacea are not required to make a diagnosis of granulomatous rosacea. The response to treatment may be slow, which must be the most important consideration for both the clinician and the patient. We present an otherwise healthy 62-year-old non-atopic woman with a 15-year history of episodic facial flushing, often accompanied by a burning sensation without sweating. Exclusively affecting the face, lesions had a high tendency to spread each year. The patient was a lifelong non-smoker. A seller on the local market, she spent most of her time outdoors. She had no positive family history of rosacea. At the time of presentation, she was not taking any medications, except for topical neutral creams. Multiple reddish-brown papules without comedones, associated with telangiectasia were ...

Journal of Dermatology Research, 2020

A 7 year old girl presented at our clinic with a 3 months history of cutanuous nodule on her face, which had gradually increased in size, non painless and pruritic. The dermatological examination revealed a 2 cm size firm erythematosis nodule, yellowish in the center, on the mental region. There was no mucosal involvement. The general physical examination was normal, with no signs of lymph node enlargement.

Anais Brasileiros de Dermatologia, 2016

Granuloma faciale is a chronic, benign, cutaneous vasculitis with well-established clinical and morphological patterns, but with an unknown etiology. This study describes clinical and pathologic aspects of patients diagnosed with granuloma faciale. The authors analyzed demographic, clinical, morphological and immunohistochemical data from patients with a final diagnosis of granuloma faciale, confirmed between 1998 and 2012. There was a proportional and mixed inflammatory infiltrate, Grenz zones were present in almost all the samples. Immunophenotyping confirmed a higher intensity of T lymphocytes than B lymphocytes in thirteen samples, with a predominance of T CD8 lymphocytes in 64% of cases, in contrast to the literature, which indicates that the major component is T CD4 lymphocytes. All cases were positive for IgG4 but the majority (12/14) had less than 25% of stained cells. The pathogenesis of granuloma faciale remains poorly understood, making studies of morphological and immunohistochemical characterization important to better understand it.

Journal of the American Academy of Dermatology, 1988

We report a case of tinea of the face caused by Trichophyton rubrum in which the histologic changes were consistent with granuloma faciale. We recommend that local infection with dermatophytes be considered in all cases of histologic granuloma faciale, especially when the clinical presentation is atypical for this dermatosis. (J AM ACAD DERMATOL 1988;18:403-6.) Granuloma faciale is an unusual facial dermatosis characterized histologically by a dense dermal polymorphonuclear leukocyte and eosinophil infiltrate, leukocytoclastic vasculits, and regions (grenz zones) of normal collagen in the papillary dennis and surrounding the adnexa. 1 According to Graham, 2 similar histologic findings may be seen in Trichophyton rubrum infection; yet we could find no such case reports in the literature.