Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
2005, EJVES Extra
Haemangiopericytomas is a rare vascular tumour. The trunk and lower extremities are involved in most cases. Fifteen to twenty percent of haemangiopericytomas arise in the head and neck. We describe a case of a benign metachronous haemangiopericytoma in a 33-year-old man. The lesions were dealt by prompt surgical excision. This case highlights the need of close long-term follow-up of such patients with haemangiopericytoma even when benign. .
British Journal of Ophthalmology, 1984
Three cases of orbital haemangiopericytoma are presented. In one the tumour recurred after 22 years and in another after 4 months. Metastasis to the breast, which occurred in the third case, is probably the first to be reported. The management of the cases is discussed. The clinical importance of the haemangiopericytoma lies in its potentially malignant behaviour.
2014
A rare case of an intracranial haemangiopericytoma with extra-cranial extension in a 60-year-old female patients’ is presented. Intracranial haemangiopericytomas are uncommon, dural-based tumors. It is classified as a tumor of uncertain origin in the WHO system.Haemangiopericytomas arise from Pericytes of Zimmerman that surround capillaries and not archetypical meningothelial arachnoid cap cells. Most frequently they arise in soft tissue sites, but rarely present in the CNS. Macroscopically many haemangiopericytomas resemble meningioma but are distinct histologically. These tumors show more aggressive natural history. Vascular nature suggests a different therapeutic approach thus fore warning a surgeon to a potentially more challenging resection.
Current Diagnostic Pathology, 1995
Clinical and Experimental Dermatology, 2009
A 48-year-old woman presented with red papules on the thigh. Histopathological examination indicated pyogenic granuloma, and the patient was treated with total excision in 2003 and electrocauterization in 2005. Three months later, upon recurrence of the lesions, a diagnosis of composite haemangioendothelioma (CHE) was made. The patient was treated by total excision and lymph-node dissection, which revealed inguinal lymph-node metastasis. Despite the surgery, a further local recurrence occurred, subsequently treated by wide excision en bloc, with adjuvant radiotherapy and chemotherapy. Although CHE is defined as a vascular tumour with low-grade malignancy, the local recurrences and lymph-node metastases resulted in treatment difficulties in this case. Unlike earlier cases, the tumour in our patient presented as localized numerous small papulonodules, and lymph-node metastasis was detected within a relatively short time. Dermatologists and pathologists should be aware of this rare condition and include it in the differential diagnosis of vascular lesions.
Critical reviews in oncology/hematology, 2016
Kaposiform haemangioendothelioma (KHE) is a tumor of intermediate malignant potential derived from vascular endothelial cells. Due to rarity of head neck KHE (HN-KHE) this comprehensive review aims to compile, analyze and present details to develop a consensus and augment available literature on HN-KHE. A comprehensive literature search was performed on PUBMED/MEDLINE, EMBASE, CINAHL and Science Citation Index for HN-KHE using MeSH words. Statistical analysis was performed using a variety of tests. Common sites of involvement were neck 41.5%, face and scalp 32.0% and tympanomastoid region in 13.2% patients. Kasabach-Merritt phenomenon was seen in 58.5% patients. Surgical excision was performed in 37.7% patients while 39.6% patients underwent medical management/chemotherapy (CT). Significantly better disease free survival (DFS) was seen in patients undergoing surgical excision vs. CT (p=0.001), without recurrence vs. with recurrence (p=0.001) and those presenting within 0-1year of li...
Clinical Oncology, 2000
Cerebral haemangiopericytomas are rare tumours that resemble meningiomas but behave more aggressively, with a tendency to metastasize. We report two patients with haemangiopericytoma who had limited surgical resections owing to perioperative blood loss but who had massive tumour shrinkage after a course of radical radiotherapy. We suggest a more conservative surgical approach to the management of these tumours.
European Archives of Oto-rhino-laryngology, 2003
Haemangiopericytomas are vascular tumours derived from Zimmerman's pericytes; they account for about 1% of all vascular tumours. About 5% of the cases occur in the nasal cavity and usually show well-differentiated tumours with low potential for local recurrence or metastasis. The treatment of choice is surgical resection. We present a case of nasal haemangiopericytoma treated by endoscopic resection, and we emphasise the advantages of this minimally invasive method compared with traditional methods.
International Journal of Oral and Maxillofacial Surgery, 2017
Haemangiopericytoma of the head and neck (HN-HPC) is a rare neoplasm occurring in children. The rarity of the tumour poses a diagnostic and therapeutic challenge. Despite protocols that recommend the use of chemotherapy prior to surgery, no treatment standard has yet been proposed. This article reports the case of a 5-month-old infant with a rapidly growing, giant life-threatening HN-HPC that was treated successfully by two-stage surgery without adjuvant chemotherapy.
Journal of Evolution of Medical and Dental sciences, 2013
Haemangioendothelioma is an uncommon neoplasm of vascular tissue in which tumor cells are vascular cells. Its occurrence in head and neck is very rare; only twenty seven cases in English literature have been reported till date. The case described in this report is of a ten year old boy presenting in the ENT Out Patient Department of our tertiary care hospital i.e. G.R. Medical College & J.A Group of Hospitals, Gwalior (M.P) with a maxillary swelling.
Veterinary Dermatology, 2002
Canine haemangiopericytoma (CHP) is a vascular neoplasm thought to be derived from pericytes. The histological pattern and immunohistochemical profile were studied in 31 CHPs. Twenty-three subjects were followed for 2 years to evaluate the correlation among tumour location, histotype, immunostaining and outcome of the disease. Of the 31 CHPs examined, 20 exhibited a perivascular whorled pattern, 8 were storifom and 3 were epithelioid. All tumours were positive for vimentin and negative for cytokeratin, factor VIII-related antigen, glial fibrillary acidic protein and S-100 protein. Seventeen CHPs were positive for actin and nine co-expressed desmin. Six CHPs were also positive for CD34 antigen. The panel of immunohistochemical markers used confirmed the vascular lineage of CHP and aided in the exclusion of other mesenchymal tumours. Of the 23 dogs submitted to follow-up, 6 had recurrence or metastases of the primary tumour. The epithelioid pattern or a noncutaneous location were associated with a poorer prognosis.
European Journal of Cardio-Thoracic Surgery, 1999
Haemangiopericytoma is a rare, highly vascular, slow-growing tumour which has both malignant and benign varieties. We report a case of a 63-year-old man in whom it was treated by initial radiotherapy followed by complete surgical excision. The preoperative radiotherapy markedly reduced the vascularity of the tumour. A brief review of the pathology and nature of tumour is provided. q
Oral Oncology Extra, 2006
Haemangiopericytoma is a rare vascular neoplasm arising from pericytes in the walls of the capillaries and venules. This tumor is reported to occur mostly in lower extremity and retro peritoneum with rare occurrence in the head and neck region. Generally they are slow growing, locally infiltrative and aggressive, with various rates of pleomorphism and malignant potential. Clinical presentations of these tumors are characteristically non-specific and diagnostic modalities are of little help. Surgery remains the gold standard of the treatment with additional benefits if adjuvant RT is taken. Here we report a case of haemangiopericytoma arising in the base of the tongue with a brief review of the literature. To our knowledge this is the first case in this location to be reported in the English literature.
International Orthopaedics, 1999
A 49-year-old woman had a haemangiopericytoma in the distal third of the arm, which is an extremely rare location. There was no recurrence of the tumor 5 years after wide margin surgical excision.
Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale, 2011
Haemangiopericytoma is a rare soft tissue tumour, with great histological variability and unpredictable clinical and biological behaviour. The precise cell type origin is uncertain. One third of haemangiopericytomas occur in the head and neck area, but only a few cases have been reported regarding localization at the parapharyngeal space. Herewith, case is presented of a 54-year-old female, referred to our Department due to a parapharyngeal space tumour with non-specific imaging characteristics. The patient underwent radical excision of the tumour with a trans-cervical sub-mandibular approach. The histolopathologic examination revealed a neoplasm with the characteristic features of haemangiopericytoma. One year later, during the scheduled follow-up, the computerized tomography scan showed no evidence of recurrence or residual disease. The pre-operative evaluation of a haemangiopericytoma must include a thorough imaging evaluation with computerized tomography and magnetic resonance i...
Oncology letters, 2012
Haemangiopericytoma (HPC) is a mesenchymal neoplasm accounting for a minority of all vascular tumours. HPC mostly arises in the lower extremities and the retroperitoneum, while the head and neck area is the third most common site. The majority of HPCs are histologically benign. However, a small percentage possess atypical features, such as a high mitotic rate, high cellularity and foci of necrosis. We report a case of classical abdominal HPC that presented 7 years after the first surgical resection with thyroid metastases of malignant HPC. Microscopic examination revealed multiple hypercellular nodules with an infiltrative growth pattern. These nodules consisted of tightly packed fusiform or spindle-shaped cells with nuclear polymorphism and an increased mitotic rate. The tumour cells exhibited a marked expression of CD34. Cells were arranged around a prominent vascular network, occasionally with a 'staghorn' configuration. The results of this study support and confirm the t...
African health sciences
Haemangiopericytoma is an uncommon soft tissue sarcoma of vascular origin. It occurs more frequently in the extremities than elsewhere in the body although it can arise in any organ. Wide surgical excision is the mainstay of treatment. However, adjuvant radiotherapy and chemotherapy are desirable because the malignant nature of this tumour is frequently unpredictable. Adjuvant therapy is recommended for metastases, recurrence and incomplete resection. Long term follow up is essential in all cases as recurrence can occur several years after treatment. Where little or no experience with managing this tumor exists, it is important to be aware of its clinical behaviour and the treatment options, hence this case reports.
European Medical Journal Neurology, 2016
This paper reports a rare case of sporadic variation of haemangioblastoma (HB) presenting as multiple lesions within the posterior fossa. A whole spectrum of radiological variants of HB were seen during its natural progression in one patient. A discussion of the management algorithm taken while managing this case is provided, and there is also a literature review to outline current insights on such a rare epiphenomenon.
European Journal of Surgical Oncology (EJSO), 1997
BJR|case reports, 2020
Primary intracranial tumours rarely metastasise outside of the central nervous system (CNS). This report describes a rare case of recurrent meningeal haemangiopericytoma with extensive systemic metastases, which eventually resulted in a fatal outcome. We discuss some prevailing theories as to the rarity of extracranial metastases from primary CNS haemangiopericytoma, and elucidate the epidemiology, imaging features, differential diagnosis, treatment, and prognosis of this unusual but surprisingly aggressive meningeal tumour. Besides aggressive treatment for local tumour control, patients with primary CNS haemangiopericytoma require long-term post-treatment surveillance to detect systemic metastases.
Objective: H A E M A N G I O P E R I C Y T O M A (H P C) has been described as a variant of angiosarcoma (hemangioendothelioma) with relatively benign biological aggressiveness. It can develop anywhere there are capillaries; hence, it causes many unique problems of diagnosis and therapy. H P C is an uncommon mesenchymal neoplasm. It is believed to arise from the pericytes, contractile spindle cells that surround the capillaries and post-capillary venules. H P C immunohistochemical profile is uncertain and diagnosis is usually controversial. Differential diagnosis from synovial sarcoma, mesenchymal chondrosarcoma, fibrous histiocytoma, and solitary fibrous tumor is a medical challenge. We present an unusual case of histopathologically confirmed malignant haemangiopericytoma of the left thigh. H P C is rare tumour of adult life (fifth decade) and is uncommon in children, paediatric H P C account for less than 10 % of all cases, and less than 3% of all soft tissue sarcomas.
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.