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2013, Obstetrics & Gynecology
Therapeutic" bed rest continues to be used widely, despite evidence of no benefit and known harms. In this commentary, we summarize the Cochrane reviews of bed rest and propose an ethical argument for discontinuing this practice. Cochrane systematic reviews do not support "therapeutic" bed rest for threatened abortion, hypertension, preeclampsia, preterm birth, multiple gestations, or impaired fetal growth. This assessment has been echoed in other comprehensive reviews. Prescribing bed rest is inconsistent with the ethical principles of autonomy, beneficence, and justice. Hence, if bed rest is to be used, it should be only within a formal clinical trial.
2013
Therapeutic" bed rest continues to be used widely, despite evidence of no benefit and known harms. In this commentary, we summarize the Cochrane reviews of bed rest and propose an ethical argument for discontinuing this practice. Cochrane systematic reviews do not support "therapeutic" bed rest for threatened abortion, hypertension, preeclampsia, preterm birth, multiple gestations, or impaired fetal growth. This assessment has been echoed in other comprehensive reviews. Prescribing bed rest is inconsistent with the ethical principles of autonomy, beneficence, and justice. Hence, if bed rest is to be used, it should be only within a formal clinical trial.
Journal of SAFOG with DVD, 2012
For centuries it is common myth to advice bed rest during pregnancy. At the least pretext bed rest is advised by family members and by health care providers also. But review of literature and RCT shows that in reality bed rest does not alter the course of pregnancy in various complications. Role of bed rest has been examined in singleton, twin and triplet pregnancies but was not found useful. Prolonged bed rest is rather harmful as it causes increased calcium excretion, loss of muscle mass, financial loss and increased psychological rest for the pregnant woman and her family. Moderate exercise is advisable throughout pregnancy to maintain tone of muscles and range of movements. So till we have more proof we should be cautious in advising pregnant patients about bed rest. It can be limited activity where we feel it is not advisable to overexert her. How to cite this article Ahuja M. Bed Rest in Pregnancy and Its Related Complications: Is It Needed?. J South Asian Feder Obst Gynae 201...
Reviews, 1996
Birth, 2007
Bedrest has long been recommended for high-risk pregnancies, but recent studies question its effectiveness in improving pregnancy outcomes. To be effective, the women for whom bedrest is recommended must practice it. This study examined degree of compliance and reason for noncompliance in women for whom bedrest was recommended, and outcomes of pregnancy among high-risk women who complied compared with those who did not. The subjects were 326 high-risk pregnant women who were prescribed bedrest for preterm labor, blood pressure problems, or bleeding problems. Of that group, one-third did not comply with the bedrest recommendation. These women had more children, were not currently married, had more stress, did not attend prenatal classes, continued drinking alcohol during pregnancy, and were not trying to get pregnant compared with women who complied. Reasons for noncompliance included the need to care for children, not feeling sick, household demands, lack of partner or family support, need to work, and discomfort. The pregnancy outcomes for the women who complied were similar to those of the women who did not comply. These findings support the importance of more research on the practice of prescribing bedrest to improve pregnancy outcomes.
Cochrane Database of Systematic Reviews, 2004
2021
Background Approximately 2.6 million babies are stillborn each year globally, of which 98% occur in low- and middle-income countries (LMICs). A 2019 individual participant data meta-analysis of 6 studies from high-income countries found that maternal supine going-to-sleep position increased the risk of stillbirth. It is not clear whether this impact would be the same in LMICs, and the normal sleep behaviour of pregnant women in LMICs is not well understood. Objective Determine the prevalence of different sleeping positions among pregnant women in LMICs, and what (if any) positions were associated with stillbirth using a systematic review. Search strategy We systematically searched the databases Medline, Embase, Emcare, CINAHL and Global Index Medicus for relevant studies, with no date or language restrictions on 4 April 2020. Reference lists of included studies were also screened. Selection criteria Observational studies of maternal sleep position during pregnancy in LMICs Data coll...
Objective: To compare the effect of bed rest after intrauterine insemination for five, ten and twenty minutes on the pregnancy rate. Design: Randomized controlled trial. Setting: Integrated Fertility Center and Agial Fertility Center. Sample: Three hundred and ninety six couples with mild male factor, cervical factor, or unexplained infertility between the periods from 1/2012 to 12/2012. Methods: Intrauterine insemination with controlled ovarian hyper-stimulation. Main outcome measures: The chemical and clinical pregnancy rates. Results: The couples were randomly subdivided equally into three groups: A, B& C and they allocated for bed rest for five, 10& 20 minutes respectively after insemination, the chemical and clinical pregnancy rates in group A (6.1& 4.5% respectively) were significantly lower than in group B (18.2& 15.9% respectively), and also it were significantly lower than in group C (23.5& 19.7% respectively), but there was no statistically significant difference in the pregnancy rates between group B and C. Conclusions: Bed rest for 10 and 20 minutes after intrauterine insemination has a positive effect on the pregnancy rate, but there is no statistically significance difference between them. We recommend for at least 10 minutes after intrauterine insemination. Key words and Abbreviations Key words: Intrauterine insemination, infertility, bed rest.
2020
Doing this PhD thesis would not have been possible without the encouragement and faith of colleagues, friends, and family. Especially, I thank Bodil Møller for pulling the strings making this PhD scholarship possible, Jette Aaroe Clausen for valuable comments, colleagues in Copenhagen and Aarhus for support even though I was periodically absent, and statistician Ole Olsen for accommodating my ideas. I am grateful to my supervisor Rikke Maimburg for the continuous support through dozens of text drafts and for encouraging me to keep on searching for best evidence -even though it sometimes may have been uncomfortable and controversial. May this PhD be just the beginning of a continuous collaboration to promote ethical and evidence-based care. I'd also like to express my gratitude to Mette Juhl, my co-supervisor, for answering epidemiological questions and for being enthusiastic about our work and for the many green chair conversations. Meeting Gene Declercq in Boston for a three-month period was a delightful experience. A special thanks to Gene for sharing expertise about model building as well as discussing topics related to medicalisation in childbirth. I'm grateful to Gene for continued collaboration throughout all three papers and furthermore am thankful for his humorous and amicable ways. Writing a PhD weighs on family relations. My husband Stefan and our children Anton and Alberte allowed me my periods of absent-mindedness and a three-month research stay in Boston. The four-year PhD research period also brought new adventures and friends, and it paved the way for a fantastic road trip across the USA. I'm unconditionally thankful for the PhD grant, financed primary from University College Copenhagen and Aarhus University. Finally, thanks to the Danish Association of Midwives and Herlev Hospital for additional financial grants and to the Hanne Kjaergaard Memorial fund for the scientific award. All indicated an implicit approval of my research topic 'Medicalisation in pregnancy and childbirth' to be relevant to explore and disseminate. The three papers of the thesis ________________________________________________________________________ Paper I (Published) Cesarean section on a rise-Does advanced maternal age explain the increase? A population register-based study.
Acta Obstetricia et Gynecologica Scandinavica, 2009
Background: At present, there is insufficient evidence to guide appropriate management of women with preterm prelabor rupture of membranes (PPROM) near term. Methods and Findings: We conducted an open-label randomized controlled trial in 60 hospitals in The Netherlands, which included non-laboring women with .24 h of PPROM between 34 +0 and 37 +0 wk of gestation. Participants were randomly allocated in a 1:1 ratio to induction of labor (IoL) or expectant management (EM) using block randomization. The main outcome was neonatal sepsis. Secondary outcomes included mode of delivery, respiratory distress syndrome (RDS), and chorioamnionitis. Patients and caregivers were not blinded to randomization status. We updated a prior meta-analysis on the effect of both interventions on neonatal sepsis, RDS, and cesarean section rate. From 1 January 2007 to 9 September 2009, 776 patients in 60 hospitals were eligible for the study, of which 536 patients were randomized. Four patients were excluded after randomization. We allocated 266 women (268 neonates) to IoL and 266 women (270 neonates) to EM. Neonatal sepsis occurred in seven (2.6%) newborns of women in the IoL group and in 11 (4.1%) neonates in the EM group (relative risk [RR] 0.64; 95% confidence interval [CI] 0.25 to 1.6). RDS was seen in 21 (7.8%, IoL) versus 17 neonates (6.3%, EM) (RR 1.3; 95% CI 0.67 to 2.3), and a cesarean section was performed in 36 (13%, IoL) versus 37 (14%, EM) women (RR 0.98; 95% CI 0.64 to 1.50). The risk for chorioamnionitis was reduced in the IoL group. No serious adverse events were reported. Updating an existing meta-analysis with our trial results (the only eligible trial for the update) indicated RRs of 1.06 (95% CI 0.64 to 1.76) for neonatal sepsis (eight trials, 1,230 neonates) and 1.27 (95% CI 0.98 to 1.65) for cesarean section (eight trials, 1,222 women) for IoL compared with EM. Conclusions: In women whose pregnancy is complicated by late PPROM, neither our trial nor the updated meta-analysis indicates that IoL substantially improves pregnancy outcomes compared with EM.
European Journal of Medical and Health Sciences
Preterm delivery is defined by the World Health Organization (WHO) as occurring before 37 weeks of pregnancy or in less than 259 days following the start of a woman's last menstrual cycle The mortality rate for children under the age of five is extremely concerning. Prematurity is the leading cause of death before the age of five around the world, and even when exceptional medical care is provided, children who survive still face long-term physical, developmental, neurological, and cognitive problems. According to the World Health Organization, 15 million babies are born prematurely each year, at least three weeks before their due dates. The top obstetricians, neonatologists, geneticists, microbiologists, immunologists, epidemiologists, health policy specialists, and bioengineers at Stanford are still conducting research to learn the main reason or causes of preterm delivery as well as the science of preterm birth This article reviewed how preterm birth occurs and the risk fact...
BMC Pregnancy and Childbirth, 2023
Background Although a history of miscarriage or stillbirth has been reported to negatively affect quality of life (QOL) during the subsequent pregnancy, the association between the number of previous miscarriages or stillbirths and QOL, as well as trends in QOL during pregnancy, has not been clarified. This study sought to determine this association during early and mid-to late pregnancy. Methods Data from 82,013 pregnant women who participated in the Japan Environment and Children's Study (JECS) from January 2011 to March 2014 were analyzed. In early and mid/late pregnancy, participants completed questionnaires and QOL was assessed using the Physical and Mental Component Summary (PCS and MCS, respectively) scores from the 8-item Short-Form Health Survey (SF-8). The pregnant women were divided into four groups according to number of previous miscarriages or stillbirths (0, 1, 2, and ≥ 3), and the PCS and MCS scores in early pregnancy and mid/late pregnancy were compared between group 0 and groups 1, 2, and ≥ 3. Generalized linear mixed models were used for analysis. Results PCS score in early pregnancy was lower in group 1 (β = − 0.29, 95% confidence interval [CI] − 0.42 to − 0.15), group 2 (β = − 0.45, 95% CI − 0.73 to − 0.18), and group ≥ 3 (β = − 0.87, 95% CI − 1.39 to − 0.35) than in group 0. Group 1 and group ≥ 3 showed a trend for increased PCS score during pregnancy (β = 0.22, 95% CI 0.07 to 0.37 and β = 0.75, 95% CI 0.18 to 1.33, respectively) compared with group 0. Conclusions PCS score in early pregnancy was lower with a more frequent history of miscarriage or stillbirth. However, in terms of changes in QOL during pregnancy, pregnant women with a history of miscarriage or stillbirth showed greater increases in PCS score during mid/late pregnancy than pregnant women with no history of miscarriage or stillbirth.
Bjog: An International Journal Of Obstetrics And Gynaecology, 2015
Objective To investigate whether women with previous miscarriages or terminations have higher levels of anxiety, depression, stress, and altered behaviours in a subsequent pregnancy. Design A retrospective analysis of 5575 women recruited into the Screening for Pregnancy Endpoints (SCOPE) study, a prospective cohort study.
Background: Pregnancy in women?s life is considered unique and natural period. But when the pregnancy is at high risk, it is recommended to limit activity and treated with bed rest which disturbs natural process of pregnancy. The women develop some needs during the journey of bed rest and want support to get them fulfilled for better maternal and fetal outcome. Objective: To undertake a narrative review so as to explore the needs of high risk pregnant women during bed rest. Method: 8 studies were selected from a period of 1991-2016 after keyword searches for PubMed, EBSCO, DELNET databases and google scholarly articles. Manual searches of other relevant journals and reference list of primary articles were also done. Results: 8 studies were selected for this narrative review including 5 qualitative and 3 quantitative studies. Data analysis of 4 of the studies reported the needs of high risk pregnant women during bed rest like need for consultation due to physical problems, psychological problems, marital problems, fear and stress, need for planning various activities during bed rest, need for counselling on psychological problems, need for social support, need for assistance with emotional adaptation and bed rest. Remaining 4 studies discussed about anxiety, stress, depression and worries faced by women which are factors for arousing specific needs during bed rest in high risk pregnancy. Conclusion: Bed rest interrupts the natural process of pregnancy due to which high risk pregnant mother may sometime feel isolated. During hospitalization, the high risk pregnant mother has high level of stress, anxiety and worries. So, nurse should have a sense of responsibility to assess the needs of high risk pregnant mother and can take help of family members to cope up with the situation.
Journal of Obstetric, Gynecologic, <html_ent glyph="@amp;" ascii="&"/> Neonatal Nursing, 1997
= Objective: To describe the experience of prolonged bed rest from the perspective of women during high-risk pregnancies.
The Cochrane library, 2005
BackgroundBed rest or restriction of activity, with or without hospitalisation, have been advocated for women with hypertension during pregnancy to improve pregnancy outcome. However, benefits need to be demonstrated before such interventions can be recommended since restricted activity may be disruptive to women's lives, expensive, and increase the risk of thromboembolism.ObjectivesTo assess the effects on the mother and the baby of different degrees of bed rest, compared with each other, and with routine activity, in hospital or at home, for primary treatment of hypertension during pregnancy.Search methodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (January 2010).Selection criteriaRandomised trials evaluating bed rest for women with hypertension in pregnancy were selected.Data collection and analysisTwo review authors assessed trials for inclusion independently, and extracted data. Data were entered into RevMan software and double‐checked.Main resultsFour small trials (449 women) were included. Three were of good quality. Two trials (145 women) compared strict bed rest with some rest, in hospital, for women with proteinuric hypertension. There was insufficient evidence to demonstrate any differences between the groups for reported outcomes. Two trials (304 women) compared some bed rest in hospital with routine activity at home for non‐proteinuric hypertension. There was reduced risk of severe hypertension (one trial, 218 women; relative risk (RR) 0.58, 95% confidence interval (CI) 0.38 to 0.89) and a borderline reduction in risk of preterm birth (one trial, 218 women; RR 0.53, 95% CI 0.29 to 0.99) with some rest compared to normal activity. More women in the bed rest group opted not to have the same management in future pregnancies, if the choice were given (one trial, 86 women; RR 3.00, 95% CI 1.43 to 6.31). There were no significant differences for any other outcomes.Authors' conclusionsFew randomised trials have evaluated rest for women with hypertension during pregnancy, and important information on side‐effects and cost implication is missing from available trials. Although one small trial suggests that some bed rest may be associated with reduced risk of severe hypertension and preterm birth, these findings need to be confirmed in larger trials. At present, there is insufficient evidence to provide clear guidance for clinical practice. Therefore, bed rest should not be recommended routinely for hypertension in pregnancy, especially since more women appear to prefer unrestricted activity, if the choice were given.
Journal of midwifery and reproductive health, 2018
Background & aim: pregnancy is a normal part of life, however, high-risk pregnancy that need bed rest can be stressful and affect woman and her family. Therefore, understanding the needs of women on bed rest seems to be necessary to enhance the quality of care services. The present study was conducted to investigate the women's needs on bed rest during high-risk pregnancy and postpartum period. Methods: This qualitative study was performed among women with high-risk pregnancy using purposeful sampling method. Data were collected by conducting 31 semi-structured interviews with 21 pregnant women, 10 spouses, and 7 medical staff involved in their healthcare. Data analysis was carried out using conventional content analysis developed by Hsieh and Shannon. Results: According to the results, there were four main categories of needs entailing the need for psychosocial support, support for family and personal affairs, support for looking after children, and the need for economic support. The final category was the need for comprehensive support. Conclusion: The personal and family life of pregnant women is affected during bed rest. Accordingly, comprehensive support is needed to enable women to cope with these problems. To reach this goal, the provision of family-centered support services based on coordination among health sections, supporting organizations, charities, social workers, and systems providing psychological and consultation services are recommended.
Fertility and Sterility, 2007
To determine whether bed rest after embryo transfer leads to improved pregnancy rates (PR). Design: Randomized controlled trial. Setting: University reproductive health clinic. Patient(s): Women undergoing IVF. Intervention(s): Patients undergoing 164 cycles of IVF were randomized to 30 minutes of bed rest after embryo transfer or immediate discharge from the clinic. Main Outcome Measure(s): Clinical PR defined by visualized fetal heart beat and ongoing PR defined by viable intrauterine gestation beyond 11 weeks.
BMJ open, 2018
To evaluate whether the percentage of time spent supine during sleep in the third trimester of pregnancy could be reduced using a positional therapy device (PrenaBelt) compared with a sham device. A double-blind, randomised, sham-controlled, cross-over pilot trial. Conducted between March 2016 and January 2017, at a single, tertiary-level centre in Canada. 23 participants entered the study. 20 participants completed the study. Participants were low-risk, singleton, third-trimester pregnant women aged 18 years and older with body mass index <35 kg/m at the first antenatal appointment for the index pregnancy and without known fetal abnormalities, pregnancy complications or medical conditions complicating sleep. A two-night, polysomnography study in a sleep laboratory. Participants were randomised by computer-generated, one-to-one, simple randomisation to receive either a PrenaBelt or a sham-PrenaBelt on the first night and were crossed over to the alternate device on the second nig...
European Journal of Obstetrics & Gynecology and Reproductive Biology
BACKGROUND Preterm premature rupture of the membranes (PPROM) is defined as spontaneous rupture of the membranes before labor at less than 37 weeks of gestation. It complicates 3 percent of pregnancies but is responsible for one third of cases of preterm birth, which is the leading cause of perinatal morbidity and mortality in developed countries. PPROM etiology is still unclear but underlying infectious process, increased inflammatory pathway activation and genetic predisposition are probably involved. Latency time from PPROM to delivery is usually brief and inversely proportional to gestational age (GA) at rupture. During this time, intrauterine infection, placental abruption, umbilical cord compression or prolapse, and fetal compression and hypoxia are possible consequences. Chorioamnionitis is the major maternal consequence of PPROM. Neonatal morbidity is also higher when PPROM is complicated by chorioamnionitis but prematurity remains the major neonatal consequence after PPROM. Several studies support that prolonged latency improves fetal maturation and does not worsen neonatal prognosis, for a given GA at birth. In order to increase GA at birth, expectant management of viable pregnancies with prophylactic antibiotic administration is recommended. Antepartum bed rest is also widely prescribed, although its effectiveness to prevent preterm birth has not been demonstrated. OBJETIVE We aimed to access the impact of bed rest in latency time to delivery, chorioamnionitis incidence and other maternal and neonatal outcomes in pregnancies complicated by PPROM, thus enabling proper sample size calculation for future powered randomized controlled trial. STUDY DESIGN Pilot unblinded randomized controlled trial (1:1 allocation ratio). Simple random allocation sequence generated by the investigators and implemented by sequentially numbered sealed envelopes.
International Journal of Gynecology & Obstetrics, 2006
Introduction: As countries are designing and implementing strategies to address maternal and newborn mortality and morbidity (Millennium Development Goals 5 and 4), it appears that a large number of evidence-based obstetric practices are not used in many settings, and this is a major obstacle to the improvement of quality obstetric care. Objectives: To remind readers of the existing, relatively easy-toimplement, evidence-based interventions that are currently not being universally applied in obstetric care and, second, to foster research to expand the evidence base further for obstetric care practices and devices, especially those that could be used in resource-poor settings. Methods: We review possible reasons why changes into practices are difficult to obtain, and we list the key evidence-based interventions known to effectively deal with the main obstetric complications, with supporting references and sources of documentation. We also list some promising interventions that require more research before being recommended. Conclusion: Professionals and health services managers have a crucial role in producing the best quality obstetric and neonatal care through implementing the listed evidence-based interventions and make them accessible to all pregnant women and their newborns without delay, even in poor settings. Reasons for which progress is slow should be addressed. One of these reasons being the lack of access
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