Latest News for: wrn

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Vividion Publishes Discovery of WRN Inhibitor VVD-214 in Journal of Medicinal Chemistry

Business Wire 06 Jan 2026
SAN DIEGO--(BUSINESS WIRE)--Vividion publishes manuscript detailing the discovery and optimization of VVD-214, the company’s covalent inhibitor of WRN ... .
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Nimbus Therapeutics Announces Completion of Dose Escalation in Phase 1/2 Clinical Trial of NDI-219216, Novel WRN Inhibitor for MSI-H Tumors

Pharmiweb 19 Dec 2025
Pharmacokinetic and pharmacodynamic data indicated that NDI-219216 achieved robust WRN target engagement for more than 24 hours at multiple dose levels ... WRN is a DNA helicase required for DNA ...
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