Papers by Deepak Kumar Bandari
Indian Journal of Pharmaceutical Education and Research
SpringerPlus, 2015
We intended to assess knowledge, attitude, perception, misconception and views (KAP-MV) of family... more We intended to assess knowledge, attitude, perception, misconception and views (KAP-MV) of family members of PLWHA. A cross-sectional retrospective study conducted in Anti-retroviral centre of Mahatma Gandhi Memorial-MGM hospital, Warangal, Telangana, South-India from July to September 2014. A questionnaire containing 41 items was distributed among adult family members accompanying patients living with HIV/AIDS-PLWHA. Level of KAP-MV was categorized into poor (0-28), average (29-55) and good (56-82). Analysis was performed by Pearson's Chi square, analysis of variance and Spearman's correlation test on 41 variables using SPSS version 21 and…
ANGIOGENESIS IN METASTATIC BREAST CARCINOMA AND LATEST INNOVATIONS IN ITS THERAPY
Introduction: The World Health Organization (WHO) declared the Ebola virus disease (EVD) epidemic... more Introduction: The World Health Organization (WHO) declared the Ebola virus disease (EVD) epidemic to be a public health emergency of international concern. Healthcare workers (HCWs) are at the highest risk of infection, as they may come into contact with patients' blood or fluids. This study was conducted to assess knowledge and attitudes of HCWs towards EVD in India. Methodology: A descriptive, cross-sectional study was conducted in a multispecialty public sector referral hospital of Telangana, India. Knowledge and attitude of HCWs were evaluated using a pre-validated questionnaire. A sample of 278 participants was selected to participate in this study. The Chi-squared test was used to assess the relationship between attitudes and demographic characteristics. Logistic regression was used examine the association between knowledge and study variables. Results: Of 257 participants who responded (92.4% response rate), 157 (61.1%) were females. The majority of the respondents were physicians (n = 117, 45.5%). Radio and television were the major sources of information about EVD reported by participants (89%). Overall knowledge of HCWs was poor (mean knowledge score: 6.57 ± 2.57). Knowledge of physicians and experienced workers (≥ 10 years) was significantly higher than their respective groups. The overall attitude of the participants was positive (mean attitude score: 1.62 ± 0.57). Significant positive correlations between knowledge and attitude were observed. Conclusions: The findings indicate that participants lack basic understanding of EVD. We recommend future studies be conducted across India to identify and subsequently bridge the knowledge gaps among HCWs.
Objectives To compare the knowledge, attitudes and self-reported barriers towards adverse drug re... more Objectives To compare the knowledge, attitudes and self-reported barriers towards adverse drug reactions reporting between Bachelor of Pharmacy (BPharm) and Doctor of Pharmacy (PharmD) students in four private pharmacy colleges in Southern India. Methods A cross-sectional study was conducted among final year PharmD (n = 107) and BPharm (n = 177) students. A self-administered questionnaire was used to collect the data from the participants. The study questionnaire was subjected to face and content validity, and reliability prior to data collection. The responses of PharmD students were compared with BPharm students. Data were analysed by employing Mann–Whitney U and chi-squared tests using SPSS (version 20). Key findings PharmD students' knowledge of ADRs was higher than BPharm students based on scores on the questionnaire administered (P < 0.001). Gender was significantly correlated with the knowledge of the participants as male participants appeared to be more knowledgeable than their female counterparts (P < 0.001). Moreover, not much difference was observed between the attitudes of PharmD and BPharm students towards ADR reporting (P < 0.05). In comparison, lack of knowledge of where and how to report ADRs was the main barrier reported by BPharm students (P = 0.001). More BPharm students were of the opinion that patients should directly report ADRs as compared to PharmD students (P < 0.05). Conclusion PharmD students exhibited better knowledge of ADRs reporting than BPharm students. Future interventions should be targeted towards BPharm students to enhance their knowledge of ADRs and Pharmacovigilance.
We intended to assess knowledge, attitude, perception, misconception and views (KAP-MV) of family... more We intended to assess knowledge, attitude, perception, misconception and views (KAP-MV) of family members of PLWHA. A cross-sectional retrospective study conducted in Anti-retroviral centre of Mahatma Gandhi Memorial— MGM hospital, Warangal, Telangana, South-India from July to September 2014. A questionnaire containing 41 items was distributed among adult family members accompanying patients living with HIV/AIDS-PLWHA. Level of KAP-MV was categorized into poor (0–28), average (29–55) and good (56–82). Analysis was performed by Pearson's Chi square, analysis of variance and Spearman's correlation test on 41 variables using SPSS version 21 and p < 0.01. 538 questionnaires were distributed, response rate was (96 %). On knowledge scale, respondents had a mean score of 8.0 ± 1.7, attitude 5.8 ± 3.4, perception 23.4 ± 4.1, misconceptions 8.0 ± 2.1 and views 8.0 ± 3.9. The respondents mean score was 53.2 ± 9.1 (64.9 %). Overall, level of education, marital status, religious beliefs, and employment status has significant (p < 0.001) associations with KAP-MV. Knowledge was significantly correlated with respondents' attitude (r = −0.15, p < 0.001), perception (0.39; p < 0.001), and views (0.381; p < 0.001). Family members of PLWHA with less knowledge score had more negative attitude, perception and views. Level of education, marital status, religious beliefs and employment status were identified as key barriers. Interventions targeting family members of PLWHA are warranted. Practice implications are as follows: • Encourage role of family members. • Deploy interventions. • Minimize barriers. • Change misconceptions. Keywords: People living with human immune virus (HIV) acquired immune deficiency syndrome (AIDS)—PLWHA, PLWHA adult family member, AIDS, HIV, Knowledge attitude perception misconception views (KAP-MV)
Objectives: To assess the beliefs, attitudes and self‑use of Ayurveda, Yoga and Naturopathy,
Unan... more Objectives: To assess the beliefs, attitudes and self‑use of Ayurveda, Yoga and Naturopathy,
Unani, Siddha, and Homeopathy (AYUSH) medicines among senior pharmacy students.
Methodology: This was a descriptive cross‑sectional study conducted among pharmacy
students in four pharmacy schools located in Andhra Pradesh in South India. This study was
conducted from the August to September 2014. The study population included all pharmacy
students enrolled in Doctor of Pharmacy, Bachelor of Pharmacy and Diploma in Pharmacy
programs in studied pharmacy schools. The pretested AYUSH survey had 8 questions on
AYUSH related beliefs and 8 question on AYUSH related attitudes. The survey also asked
participants about AYUSH related knowledge, frequency of use of AYUSH and the reason for
using AYUSH. The data analysis was performed using SPSS Version 20. Chi‑square test and
Mann–Whitney U‑test were employed to study the association between the independent and
dependent variables. Results: A total of 428 pharmacy students participated in the survey.
32.2% of the study population was females and 32.5% of the population resided in rural
areas. Males were more likely to have positive beliefs about AYUSH when compared to
females (odd ratio [OR] = 4.62, confidence interval [CI] = 2.37−8.99, P < 0.001). Similarly,
students living in hostels were more positive in their beliefs about AYUSH compared with
students living at home (OR = 2.14, CI = 1.12−4.07, P < 0.05). Students living in hostel
also had a positive attitude about AYUSH use (OR = 1.74, CI = 1.03−2.93, P < 0.05).
Conclusion: Pharmacy students held favorable attitude and beliefs about AYUSH use. This baseline survey provides important information about the pharmacy student’s perception about AYUSH. Further research is needed to explore the reasons that shape the pharmacy student’s beliefs and attitudes about AYUSH.
Background: Family members are of particular importance in supporting the People Living With HIV/... more Background: Family members are of particular importance in supporting the People Living With HIV/AIDS (PLWHA). We intended to assess the knowledge, attitude, perception, misconceptions of PLWHA relative views (KAP-MV) regarding HIV/AIDS in South India. Methodology: A cross-sectional self-administered questionnaire containing 50 items was distributed among the PLWHA relatives visitingAntiretroviral therapy (ART) centre in Mahatma Gandhi Memorial (MGM) tertiary care government hospital, Warangal city from April-July 2014. A structured open-ended questionnaire concerning 4 variables, 1) sociodemographic details (9 items); 2) knowledge, attitude, misconceptions about HIV/AIDS (5 items of each); 3) perception towards the possible causes of HIV infections (14 items) and 4) respondents views to prevent HIV infections (12 questions) was administered during the study period. Participants indicated categorically [Yes=2 points, No=0 points] were summed to a nominal measure of all items yielding a range of value from 0-82. Using these, score the level of KAP-MV was categorized into poor (0-33), average (34-50) and good (51-82). Pearson's chi-square, analysis of variance (one-way ANOVA) and Spearman's Correlation test was conducted on 41 variables towards KAP-MV with PLWHA sociodemographic characters using SPSS version 21. A p-value of p<0.01 was considered statistically significant.
Results: Although 515 questionnaires were returned, representing 96% of those distributed and 58.4% of them were students. On the scale of knowledge the subjects had a mean score of 8±1.76, Attitude-5.80±3.47, Perception-23.44±4.19, Misconceptions-8.03±2.19 and respondent views-8.0±3.98. Total (41 items) subjects mean score of 66.28±9.18 (81%). High score indicated a positive KAP-V and less misconception towards HIV/AIDS. Overall, level of education, marital status, religious beliefs, and employment status has significant (P=0.000) association with KAP-MV. Knowledge was significantly correlated with attitude (r= -0.15, p<0.001), perception (0.39;0.000), and respondent views (0.381;0.000);PLWHA relatives with less knowledge score had more negative attitude, perception and views towards preventing HIV infections. Further, misconceptions were highly associated with PLWHA relatives with negative views (0.337;0.000) and perceptions (0.201;0.000).
Conclusion: PLWHA relatives had shown satisfactory levels (81%) of KAP-MV toward HIV/AIDS in high prevalent Warangal district, South India. To increase the awareness and decrease the negative views PLWHA families (as well as general population) should be more actively involved and instructed about all aspects of AIDS.
Keywords:PLWHA, AIDS, HIV, Family Care, Attitude, South India
Antipyretic activity of whole plant of Lepidagathis cristata Willd. in Brewer’s Yeast induced Hyperpyrexia rats, Jan 2012
The objective of the present work was to study the antipyretic activity of whole plant of Lepidag... more The objective of the present work was to study the antipyretic activity of whole plant of Lepidagathis cristata Willd, belongs to family Acantahaceae. The Petroleum ether extract was taken for the study and evaluated for antipyretic activity using Brewer’s yeast induced pyrexia in Wister strain albino rats. The Petroleum ether extracts at a dose of 100mg/kg & 200mg/kg were evaluated for antipyretic activity. The extract of Lepidagathis cristata plant showed a significant (P < 0.01) dose dependent antipyretic effect in yeast induced elevation of body temperature in experimental rats. The Petroleum ether extracts of Lepidagathis cristata plant have significant antipyretic activity when compared with the standard drug.
Keywords: Lepidagathis cristata, Antipyretic activity, Brewer’s yeast.
Formulation and evaluation of pantoprazole buccal patches, Mar 2012
Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of interest ... more Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of interest since the early 1980s. Advantages associated with buccal drug delivery have rendered this route of administration useful for a variety of drugs. The goal of the present investigation was to design and evaluate mucoadhesive buccal patches of pantoprazole which offers an attractive route of administration for systemic drug delivery. Pantoprazole (dose, 10-40mg) is proton pump inhibitor used in treatment of erosion and ulceration of the esophagus caused by gastro esophageal reflux disease. Its oral bioavailability is 77% metabolized in the liver by cyp-450 system. The patches were prepared and evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, and In vitro release studies were conducted for pantoprazole loaded patches in phosphate buffer (pH, 7.4) solution.
Keywords: Pantoprazole, HPMC, PVP, PG.
In vivo analgesic activity of petroleum ether extract of Boswellia ovalifoliolata Linn Leaves, Jan 2012
Boswellia ovalifoliolata Linn. (Family: Burseraceae) Leaves were extracted in petroleum ether (60... more Boswellia ovalifoliolata Linn. (Family: Burseraceae) Leaves were extracted in petroleum ether (60°-80°C) to evaluate for centrally acting analgesic potential using tail immersion and peripheral pharmacological actions using acetic acid induced writhing test in mice. Boswellia ovalifoliolata Linn. extracts were found to have been significant (p<0.05) analgesic activity at the oral dose of 200 & 400 mg/kg b. wt., in the tested models. In tail immersion test Boswellia ovalifoliolata Linn. extracts showed increased tail withdrawal time whereas in acetic acid induced writhing test Boswellia ovalifoliolata Linn. extracts showed reduced number of writhes at two dose levels, which are significant (p<0.05) compared to control. The results obtained support the use of leaves of Boswellia ovalifoliolata Linn. extracts in painful conditions acting both centrally and peripherally.
Keywords: Boswellia ovalifoliolata Linn., Writhing Test, Tail Immersion Test.
Book Reviews by Deepak Kumar Bandari
An integrated approach to clinical practice
Conference Presentations by Deepak Kumar Bandari
American Association of Clinical Pharmacy - 2015
Asian Conference on Clinical Pharmacy - 2012
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Papers by Deepak Kumar Bandari
Unani, Siddha, and Homeopathy (AYUSH) medicines among senior pharmacy students.
Methodology: This was a descriptive cross‑sectional study conducted among pharmacy
students in four pharmacy schools located in Andhra Pradesh in South India. This study was
conducted from the August to September 2014. The study population included all pharmacy
students enrolled in Doctor of Pharmacy, Bachelor of Pharmacy and Diploma in Pharmacy
programs in studied pharmacy schools. The pretested AYUSH survey had 8 questions on
AYUSH related beliefs and 8 question on AYUSH related attitudes. The survey also asked
participants about AYUSH related knowledge, frequency of use of AYUSH and the reason for
using AYUSH. The data analysis was performed using SPSS Version 20. Chi‑square test and
Mann–Whitney U‑test were employed to study the association between the independent and
dependent variables. Results: A total of 428 pharmacy students participated in the survey.
32.2% of the study population was females and 32.5% of the population resided in rural
areas. Males were more likely to have positive beliefs about AYUSH when compared to
females (odd ratio [OR] = 4.62, confidence interval [CI] = 2.37−8.99, P < 0.001). Similarly,
students living in hostels were more positive in their beliefs about AYUSH compared with
students living at home (OR = 2.14, CI = 1.12−4.07, P < 0.05). Students living in hostel
also had a positive attitude about AYUSH use (OR = 1.74, CI = 1.03−2.93, P < 0.05).
Conclusion: Pharmacy students held favorable attitude and beliefs about AYUSH use. This baseline survey provides important information about the pharmacy student’s perception about AYUSH. Further research is needed to explore the reasons that shape the pharmacy student’s beliefs and attitudes about AYUSH.
Results: Although 515 questionnaires were returned, representing 96% of those distributed and 58.4% of them were students. On the scale of knowledge the subjects had a mean score of 8±1.76, Attitude-5.80±3.47, Perception-23.44±4.19, Misconceptions-8.03±2.19 and respondent views-8.0±3.98. Total (41 items) subjects mean score of 66.28±9.18 (81%). High score indicated a positive KAP-V and less misconception towards HIV/AIDS. Overall, level of education, marital status, religious beliefs, and employment status has significant (P=0.000) association with KAP-MV. Knowledge was significantly correlated with attitude (r= -0.15, p<0.001), perception (0.39;0.000), and respondent views (0.381;0.000);PLWHA relatives with less knowledge score had more negative attitude, perception and views towards preventing HIV infections. Further, misconceptions were highly associated with PLWHA relatives with negative views (0.337;0.000) and perceptions (0.201;0.000).
Conclusion: PLWHA relatives had shown satisfactory levels (81%) of KAP-MV toward HIV/AIDS in high prevalent Warangal district, South India. To increase the awareness and decrease the negative views PLWHA families (as well as general population) should be more actively involved and instructed about all aspects of AIDS.
Keywords:PLWHA, AIDS, HIV, Family Care, Attitude, South India
Keywords: Lepidagathis cristata, Antipyretic activity, Brewer’s yeast.
Keywords: Pantoprazole, HPMC, PVP, PG.
Keywords: Boswellia ovalifoliolata Linn., Writhing Test, Tail Immersion Test.
Book Reviews by Deepak Kumar Bandari
Conference Presentations by Deepak Kumar Bandari
Unani, Siddha, and Homeopathy (AYUSH) medicines among senior pharmacy students.
Methodology: This was a descriptive cross‑sectional study conducted among pharmacy
students in four pharmacy schools located in Andhra Pradesh in South India. This study was
conducted from the August to September 2014. The study population included all pharmacy
students enrolled in Doctor of Pharmacy, Bachelor of Pharmacy and Diploma in Pharmacy
programs in studied pharmacy schools. The pretested AYUSH survey had 8 questions on
AYUSH related beliefs and 8 question on AYUSH related attitudes. The survey also asked
participants about AYUSH related knowledge, frequency of use of AYUSH and the reason for
using AYUSH. The data analysis was performed using SPSS Version 20. Chi‑square test and
Mann–Whitney U‑test were employed to study the association between the independent and
dependent variables. Results: A total of 428 pharmacy students participated in the survey.
32.2% of the study population was females and 32.5% of the population resided in rural
areas. Males were more likely to have positive beliefs about AYUSH when compared to
females (odd ratio [OR] = 4.62, confidence interval [CI] = 2.37−8.99, P < 0.001). Similarly,
students living in hostels were more positive in their beliefs about AYUSH compared with
students living at home (OR = 2.14, CI = 1.12−4.07, P < 0.05). Students living in hostel
also had a positive attitude about AYUSH use (OR = 1.74, CI = 1.03−2.93, P < 0.05).
Conclusion: Pharmacy students held favorable attitude and beliefs about AYUSH use. This baseline survey provides important information about the pharmacy student’s perception about AYUSH. Further research is needed to explore the reasons that shape the pharmacy student’s beliefs and attitudes about AYUSH.
Results: Although 515 questionnaires were returned, representing 96% of those distributed and 58.4% of them were students. On the scale of knowledge the subjects had a mean score of 8±1.76, Attitude-5.80±3.47, Perception-23.44±4.19, Misconceptions-8.03±2.19 and respondent views-8.0±3.98. Total (41 items) subjects mean score of 66.28±9.18 (81%). High score indicated a positive KAP-V and less misconception towards HIV/AIDS. Overall, level of education, marital status, religious beliefs, and employment status has significant (P=0.000) association with KAP-MV. Knowledge was significantly correlated with attitude (r= -0.15, p<0.001), perception (0.39;0.000), and respondent views (0.381;0.000);PLWHA relatives with less knowledge score had more negative attitude, perception and views towards preventing HIV infections. Further, misconceptions were highly associated with PLWHA relatives with negative views (0.337;0.000) and perceptions (0.201;0.000).
Conclusion: PLWHA relatives had shown satisfactory levels (81%) of KAP-MV toward HIV/AIDS in high prevalent Warangal district, South India. To increase the awareness and decrease the negative views PLWHA families (as well as general population) should be more actively involved and instructed about all aspects of AIDS.
Keywords:PLWHA, AIDS, HIV, Family Care, Attitude, South India
Keywords: Lepidagathis cristata, Antipyretic activity, Brewer’s yeast.
Keywords: Pantoprazole, HPMC, PVP, PG.
Keywords: Boswellia ovalifoliolata Linn., Writhing Test, Tail Immersion Test.