Antonia Lukito

Universitas Pelita Harapan, Cardiovascular, Post-Doc

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I currently work as Interventional cardiologist and electrophysiologist at a private academic hospital, also assigned as head of Cardiovascular Department at Pelita Harapan University. My PhD dissertation is about the mechanism of coronary calcification.

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Eric S . Kim (UBC)

University of British Columbia

David Seamon

Kansas State University

Fabio A. Madau

Università di Sassari

Amir Manbachi

Johns Hopkins University

Eric Jensen

University of Warwick

Rigas Arvanitis

Institut de Recherche pour le Développement (IRD - France)

Shailesh K Tiwari

Indian Council of Agricultural Research

Karl-Heinz Leitner

AIT Austrian Institute of Technology GmbH

Johann Kirsten

University of Pretoria

Dr I. M. Rizwanul Fattah

University of Technology Sydney

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Papers by Antonia Lukito

The Significance of Hypertension Towards the Number of Vessel Involvement in CAD Patients Undergoing Coronary Angiography

Journal of Hypertension, 2015

Background: Hypertension is a well-known risk factor towards the development of Coronary Artery D... more Background: Hypertension is a well-known risk factor towards the development of Coronary Artery Disease (CAD). However, the extent to which the presence of hypertension affects the severity of CAD is not yet fully studied. This study hopes to lightly touch on the link between hypertension and the severity of CAD. Objective: The objective of this study is to analyze the association between the presence of hypertension as a risk factor with the severity of CAD, roughly represented by the number of coronary vessels involved identified through coronary angiography. Method: We studied several prevalent risk factorsin 228 patients admitted for elective coronary angiography. We identified hypertension amongst other risk factors such as, diabetes, smoking habit, family history, and dyslipidemia using the angiography report. The number of coronary vessel involvement were classified as, Minor CAD without any significant vessel stenosis, CAD 1-Vessel Disease (VD), CAD 2-VD, and CAD 3-VD; excluding any involvement of the Left Main Coronary Artery. Results: Of the 228 patients, 129 (55.6%) patients were present with hypertension. Patients who were present with hypertension, as compared with those without, independently increased the odds of an increased number of coronary vessel involvement in a proportional-odds logistic regression model (Odds Ratio, 1.65; 95% CI 1.02–2.67; p-value <0.05) across four categories. Conclusion: Hypertension is a significant risk factor in every level of CAD represented by the increased number of coronary vessels involved. This result may indicate that hypertension not only plays a part in the development of, but also influences the severity of CAD.

Higher risk of adverse cardiovascular outcomes in women with type 2 diabetes mellitus: an umbrella review of systematic reviews

European Heart Journal

Funding Acknowledgements Type of funding sources: None. Background Previous studies have shown th... more Funding Acknowledgements Type of funding sources: None. Background Previous studies have shown that females with type 2 diabetes mellitus (T2DM) may have an excess mortality risk compared to males. Furthermore, other studies have reported sex differences in managing cardiovascular risk factors, such as controlling hypertension and hypercholesterolemia. Purpose With the growing evidence from systematic reviews examining the sex differences in cardiovascular outcomes for patients with T2DM, an umbrella review is an essential next step to synthesising and assessing the strength of the available evidence. Methods Medline and Embase were searched from inception till 7th August 2022 for systematic reviews and meta-analyses studying the effects of sex on cardiovascular outcomes in T2DM patients. Results from reviews were synthesised with a narrative synthesis, with a tabular presentation of findings and forest plots for reviews that performed a meta-analysis. AMSTAR 2 tool was used to asse...

Antonia Lukito

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