Papers by Rossano Fiorelli
Open Journal of Clinical & Medical Case Reports
It is estimated that goiters occur in about 5% of the worlds population and that they constitute ... more It is estimated that goiters occur in about 5% of the worlds population and that they constitute about 7% of mediastinal tumors [1]. We present a case in which a diving goiter was much larger in size than those normally published in the literature worldwide.
Research Square (Research Square), Aug 14, 2019
Background: Obesity is a global problem and is associated with numerous diseases, including endom... more Background: Obesity is a global problem and is associated with numerous diseases, including endometrial disorders in postmenopausal women, such as adenocarcinoma, hyperplasias and endometrial polyps, and with risk of malignant transformation of these structures. We aimed to evaluate the influence of body mass index (BMI) on the cell proliferation markers (Bcl-2 and Ki67) on the endometrial polyps in postmenopause women. Methods: Prospective cross-sectional study using immunohistochemical analysis of the expression of the cell proliferation marker (Ki67) and an antiapoptotic gene (Bcl-2) in endometrial polyps, in postmenopausal women. The polyps were identified by hysteroscopy and all were removed. The patients were divided into two groups related to BMI: a)
Journal of Personalized Medicine, Jun 25, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Revista do Colégio Brasileiro de Cirurgiões, 2022
Conflito de interesses: não. Fonte de financiamento: nenhuma.
Anais da Academia Nacional de Medicina, 2020
Anais da Academia Nacional de Medicina, 2022
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are established cause... more Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are established causes of morbidity and mortality in critically ill patients. When interest in postoperative IAH after major surgery, vascular surgery, trauma and critically ill patients emerged in the 1980s, ACS was the only recognized clinical syndrome and decompressive laparotomy the only definitive treatment. Since then, less extreme elevations in intra-abdominal pressure (IAP), defined as IAH, have been recognized as highly prevalent among all types of patients admitted to the intensive care unit (ICU). Significant advances in understanding the pathophysiology, diagnosis, and treatment of IAH and ACS have occurred in recent decades. The importance of IAH has been studied specifically in critically ill patients, leading to a better understanding of the mechanisms of organ dysfunction due to increased IAP and earlier opportunities for therapeutic intervention. In addition, medical and minimally invasive techniques have been developed and reported to be potentially effective in small studies.
Anais da Academia Nacional de Medicina, 2022
The FASEB Journal
BackgroundFaulty innervation from pudendal nerve branches is a common cause of anal incontinence,... more BackgroundFaulty innervation from pudendal nerve branches is a common cause of anal incontinence, a condition that can severely impact quality of life. Current treatments include medication, rehabilitation, surgical repair of the sphincter and conversion to a definitive stoma. All these options have yielded unsatisfactory results to restore the function of the external anal sphincter, with success rates of approximately 50% (Thinn et al., 2013). Over the last 15 years, an increasing interest in exploring the possibilities of restoring rectum and bladder sphincteric function by means of nerve transfers has produced a number of experimental studies in animal models, indicating promising results (Bao et al., 2018).ObjectiveOur goal was to test the feasibility of dissecting a fascicle of the tibial component of the sciatic nerve to see if it would be long enough to serve as a “donor nerve” for coaptation with the pudendal nerve, in both gluteal and perineal regions.MethodsWe dissected t...
Journal of Personalized Medicine
Background: Methotrexate (MTX), sulfonamides, hydroxychloroquine, and leflunomide have consistent... more Background: Methotrexate (MTX), sulfonamides, hydroxychloroquine, and leflunomide have consistently resulted in remission with relatively mild to moderate adverse effects in patients with rheumatoid arthritis (RA). Modern medications outperform traditional treatments in that they target the pathological processes that underlie the development of RA. Methods: Following PRISMA guidelines, the authors accomplished a systematic review of the clinical efficacy of RA drugs, including the biologics such as Tumor Necrosis Factor-alpha inhibitors (TNF-α i) like Etanercept, Infliximab, Golimumab, and Adalimumab, kinase inhibitors (JAK inhibitors including Baricitinib and Tofacitanib), SyK inhibitors like Fos-tamatinib, MAPK inhibitors such as Talmapimod, T-cell inhibitors (Abatacept), IL6 blockers (Tocilizumab), and B cells depleters (Rituximab). These drugs have been found to increase remission rates when combined with MTX. A bioinformatics-based network was designed applying STRING-MODEL an...
Rev. bras. cir. plást, 2018
Boletim da Academia Nacional de Medicina, 2022
Journal of Personalized Medicine, Mar 29, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Journal of Vascular Access, Jul 3, 2021
Background: The functional autologous arteriovenous fistula is considered the best vascular acces... more Background: The functional autologous arteriovenous fistula is considered the best vascular access for patients on hemodialysis. Some fistulae exhibit maturation problems after creation and do not reach adequate vessel diameter and flow in dialysis. The aim of this study was to describe our technique of oversized balloon angioplasty for assisted maturation of arteriovenous fistulae to accelerate the cannulation and to decrease the time of catheter use and its outcome. Methods: A retrospective analysis of balloon-assisted procedures for maturation failure was performed in a single center between October 2011 and January 2019. Patients underwent imaging procedures to identify stenosis, followed by angioplasty using oversized high-pressure balloons from the anastomosis to the deep venous outflow tract. The flow volume, time interval of use of the fistula and removal of the catheter, patency rates, and complications rates were evaluated. Results: Seventy-eight patients underwent 124 balloon angioplasty procedures. Technical and clinical success was achieved in 91% of the cases. In patients in whom maturation was successful, the fistula was cannulated in a mean time of 5 days after the procedure (range, 1–20 days). On average, catheter removal was performed 14 days (range, 5–33 days) after the maturation procedure. The mean flow volume in the fistula before the procedure was 276 ml/min (range, 122–488 ml/min) and 24 h after the maturation was 1014 ml/min (range, 760–1800 ml/min). The primary patency rate at 3, 6, and 12 months was 87.3%, 66.2%, and 50.7%, respectively. Assisted primary patency was 100% at 3 months, 92.9% at 6 months, and 90.0% at 12 months. Minor complications occurred in 18% of cases, and major complications in 4.8%. Conclusions: The oversized balloon-assisted arteriovenous fistula maturation technique is safe and effective, allowing the cannulation of the fistulae a few hours or days after the procedure and decreasing the time of catheter use.
Journal of Personalized Medicine, Feb 17, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Jornal Vascular Brasileiro, 2022
Dystrophic calcinosis cutis in chronic venous disease of the lower limbs Calcinose distrófica cut... more Dystrophic calcinosis cutis in chronic venous disease of the lower limbs Calcinose distrófica cutânea na doença venosa crônica de membros inferiores
Revista do Colégio Brasileiro de Cirurgiões, 2022
Protocolo para a profilaxia do tromboembolismo venoso em cirurgia de varizes dos membros inferiores
Revista do Colégio Brasileiro de Cirurgiões, Jul 16, 2018
Revista do Colégio Brasileiro de Cirurgiões, 2023
Revista do Colégio Brasileiro de Cirurgiões, 2023
Bloqueio do plano do músculo serrátil guiado por ultrassonografia associado à sedação venosa como... more Bloqueio do plano do músculo serrátil guiado por ultrassonografia associado à sedação venosa como técnica anestésica em cirurgia de linfadenectomia axilar: uma série de casos prospectiva The protocol was approved by the Ethics in Research Committee of the National Cancer Institute (CEP-INCA), Rio de Janeiro, Brazil (President CHD Silva) on June 2, 2018 (registration number CAAE 89037818.0.0000.5274) registered on the ClinicalTrials. gov on June 25, 2018 (NCT03740815). Specific informed consent for this research was obtained from all participants. This study consisted of a single-center, prospective case series, described according to the Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines 4. We evaluated patients with skin and soft Cientific Communication
Jornal Vascular Brasileiro, 2022
Copyright© 2022 Os autores. Este é um artigo publicado em acesso aberto (Open Access) sob a licen... more Copyright© 2022 Os autores. Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution, que permite uso, distribuição e reprodução em qualquer meio, sem restrições desde que o trabalho original seja corretamente citado. Calcinose distrófica cutânea na doença venosa crônica de membros inferiores Dystrophic calcinosis cutis in chronic venous disease of the lower limbs
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Papers by Rossano Fiorelli